CAS: 152302-45-9; N-[2-(7-Hydroxynaphthalen-1-yl)Ethyl]Acetamide

主要参考文献

参考标题:Design And Synthesis Of Naphthalenic Derivatives As New Ligands At The Melatonin Binding Site Mt3
作者:Véronique Leclerc,Mohamed Ettaoussi,Marouan Rami,Amaury Farce,Jean Albert Boutin,Philippe Delagrange,Daniel-Henri Caignard,Pierre Renard,Pascal Berthelot,Saïd Yous |发布日期:2011.5
摘要:No-N-Acetyltryptamine) Have Been Synthesized And Evaluated As Melatonin Receptor Ligands. Introduction Of A Methoxycarbonylamino Substituent At The C-7 Position Of The Naphthalenic Nucleus Yields Mt3 Selective Ligands. This Selectivity Can Be Modulated With Suitable Variations Of The C-7 Position And The Acyl Group On The C-1 Side Chain. We Identified New Series Of Compounds With Affinity For The Mt3

合成参考文献

参考文献:10.1021/jm9810093
摘要:Mor M, Rivara S, Silva C, Bordi F, Plazzi PV, Spadoni G, Diamantini G, Balsamini C, Tarzia G, Fraschini F, Lucini V, Nonno R, Stankov BM. Melatonin receptor ligands: synthesis of new melatonin derivatives and comprehensive comparative molecular field analysis (CoMFA) study. J Med Chem. 1998 Sep 24;41(20):3831–44. doi: 10.1021/jm9810093.