CAS: 1483-07-4; (S)-2-Amino-3-Ureidopropanoic Acid

该化合物是一种自然发生的化合物,被归类为苯球甘蓝,主要来源于Albizia julibrissin植物,通常称为丝绸树,该植物展示了一系列生物活动,包括抗氧化剂,抗炎和潜在的抗微生物特性,使其对药理学研究感兴趣.化学上,albiziziin的特征是其芬诺氏结构,有助于其再活动以及与各种生物系统的互动.其有机溶剂中的溶解性和水中的溶解性是芬氏化合物的典型特征,影响其生物利用率和治疗应用中的功效.此外,Albizziin的安全特征和潜在健康惠益是正在进行的研究的主题,特别是在传统医学方面.总的来说,albizziin是天然产品化学中一个令人着味的研究领域,对健康和环境科学都有影响.

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CAS号52809-07-1 异喹啉酸(mM/ml) | CAS号590-28-3 氰酸钾 | CAS号1482-97-9 L(+)-2,3-二氨基丙氨酸盐酸盐 | CAS号515-94-6 2,3-二氨基丙酸

合成工艺路线路线简述

    📜使君子氨酸置于platinum(Iv) Oxide 氢气体系中,用 水 用作溶剂,化学反应 3.0H,反应生成L-脲基丙氨酸
    参考文献:L-半胱氨酸的合成:对映体高效合成β-氨基丙氨酸衍生物的一般方法
    标题:L-半胱氨酸的合成:对映体高效合成β-氨基丙氨酸衍生物的一般方法
    摘要:描述了对映体高效合成β-氨基丙氨酸衍生物的一般方法,该方法涉及通过氮杂环丁酮将氨基取代基从α羧基分子内转移到β-碳原子,并将其应用于神经兴奋性喹喹酸的高效合成.光学上纯净的状态.
    Doi:10.1039/c39850000256

    海关参考信息

    专利信息


    专利号:US-2023037284-A9
    优先权日:2018-11-30
    标题:Combination therapy of peptidomimetic macrocycles
    发明人:GUERLAVAIS VINCENT; ANNIS DAVID ALLEN
    权利人:AILERON THERAPEUTICS INC
    摘要:The present disclosure describes the synthesis of peptidomimetic macrocycles and methods of using peptidomimetic macrocycles to treat a condition. The present disclosure also describes methods of using peptidomimetic macrocycles in combination with at least one additional pharmaceutically-active agent for the treatment of a condition, for example, cancer.

    专利号:US-2025084410-A1
    优先权日:2015-01-12
    标 题:Incorporation of unnatural nucleotides and methods thereof
    发明人:PTACIN JEROD; MALYSHEV DENIS A; CAFFARO CAROLINA E
    权利人:SYNTHORX INC
    摘要:Disclosed herein are methods, compositions and kits for the synthesis of proteins which comprises unnatural amino acids that utilize a mutant tRNA.

    专利号:US-11225655-B2
    优先权日:2010-04-16
    标题:Bi-functional complexes and methods for making and using such complexes
    发明人:GOULIAEV ALEX HAAHR; FRANCH THOMAS; GODSKESEN MICHAEL ANDERS; JENSEN KIM BIRKEBAEK
    权利人:GOULIAEV ALEX HAAHR; FRANCH THOMAS; GODSKESEN MICHAEL ANDERS; JENSEN KIM BIRKEBAEK; NUEVOLUTION AS
    摘要:The present invention is directed to a method for the synthesis of a bi-functional complex comprising a molecule part and an identifier oligonucleotide part identifying the molecule part. A part of the synthesis method according to the present invention is preferably conducted in one or more organic solvents when a nascent bi-functional complex comprising an optionally protected tag or oligonucleotide identifier is linked to a solid support, and another part of the synthesis method is preferably conducted under conditions suitable for enzymatic addition of an oligonucleotide tag to a nascent bi-functional complex in solution.

    专利号:US-2018371021-A1
    优先权日:2017-05-11
    标 题 :Peptidomimetic macrocycles and uses thereof
    发明人:AIVADO MANUEL; GUERLAVAIS VINCENT; OLSON KAREN
    权利人:AILERON THERAPEUTICS INC
    摘要:The present disclosure describes the synthesis of peptidomimetic macrocycles and methods of using peptidomimetic macrocycles to treat a condition. The present disclosure also describes methods of using peptidomimetic macrocycles in combination with at least one additional pharmaceutically-active agent for the treatment of a condition, for example, cancer.

    专利号:WO-2004076425-A1
    优先权日:2003-02-21
    标题:Improved synthesis of macrocyclic tetraamido compounds and new metal insertion process

    专利号:CA-3153855-A1
    优先权日:2019-10-10
    标题:Compositions and methods for in vivo synthesis of unnatural polypeptides

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献


    1: Durá MA, Flores M, Toldrá F. Purification and characterisation of a glutaminase from Debaryomyces spp.. Int J Food Microbiol. 2002 Jun 5;76(1-2):117-26.
    5: Winter HC, Dekker EE. 4-methyleneglutamine amidohydrolase from peanut leaves : preparation, catalytic properties, and immunological responses of a highly purified form of the enzyme. Plant Physiol. 1991 Jan;95(1):206-12.
    6: Richter K, Wolf G. High-affinity glutamine uptake of the rat hippocampus during postnatal development: a quantitative autoradiographic study. Neuroscience. 1990;34(1):49-55.

    合成参考文献


    参考文献:10.1128/aem.02518-08
    摘要:Kevany BM, Rasko DA, Thomas MG. Characterization of the Complete Zwittermicin A Biosynthesis Gene Cluster fromBacillus cereus. Appl Environ Microbiol. 2009 Feb 15;75(4):1144–55. doi: 10.1128/aem.02518-08.
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