CAS: 1254942-29-4; (R,E)-4-((3-(3-(Diisopropylamino)-1-Phenylpropyl)-4-(Isobutyryloxy)Benzyl)Oxy)-4-Oxobut-2-Enoic Acid

英文名称(R,E)-4-((3-(3-(Diisopropylamino)-1-Phenylpropyl)-4-(Isobutyryloxy)Benzyl)Oxy)-4-Oxobut-2-Enoic Acid
中文名称弗斯特罗定富马酸酯
IUPAC名称(R,E)-4-((3-(3-(diisopropylamino)-1-phenylpropyl)-4-(isobutyryloxy)benzyl)oxy)-4-oxobut-2-enoic acid
其它别名Fesoterodine Related Impurity 2; Fesoterodine Fumarate Ester; (2E)-2-Butenedioic Acid 1-[[3-[(1R)-3-[bis(1-Methylethyl)Amino]-1-Phenylpropyl]-4-(2-Methyl-1-Oxopropoxy)Phenyl]Methyl] Ester; Fesoterodine Impurity 8; (R,E)-4-((3-(3-(Diisopropylamino)-1-Phenylpropyl)-4-(Isobutyryloxy)Benzyl)Oxy)-4-Oxobut-2-Enoic Acid; (2E)-4-[(3-(3-Diisopropylamino-1-Phenylpropyl)-4-(2-Isobutyroyloxyphenyl))Methoxy]-4-Oxobut-2-Enoic Acid; 2-Butenedioic Acid (2E)-, 1-[[3-[(1R)-3-[bis(1-Methylethyl)Amino]-1-Phenylpropyl]-4-(2-Methyl-1-Oxopropoxy)Phenyl]Methyl] Ester; (2E)-2-Butenedioic Acid 1-[[3-[(1R)-3-[bis(1-Methylethyl)Amino]-1-Phenylpropyl]-4-(2-Methyl-1-O
CAS编号1254942-29-4
分子式:C30H39NO6分子量:509.64
产品CID: 378734
产品分类有机原料 → 苯类化合物 → 苯取代衍生物

相似结构搜索
InChIKey: CHEHSUCSZOKLSO-LECGRMGRSA-N
InChI=1S/C30H39NO6/c1-20(2)30(35)37-27-13-12-23(19-36-29(34)15-14-28(32)33)18-26(27)25(24-10-8-7-9-11-24)16-17-31(21(3)4)22(5)6/h7-15,18,20-22,25H,16-17,19H2,1-6H3,(H,32,
计算化学: 氢键受体数7.0氢键供体数1.0可旋转键数15.0

物理性质

熔点>65°C (dec,)
溶解性DMSO (Slightly, Sonicated), Methanol (Slightly)
外观形态白色至类白色固体
储存条件冰箱

MSDS等安全信息

上下游产品

fesoterodine fumarate

合成工艺路线路线简述

📜1-O-[[3-[(1R)-3-[di(Propan-2-yl)Amino]-1-Phenylpropyl]-4-(2-Methylpropanoyloxy)Phenyl]Methyl] 4-O-Ethenyl (E)-But-2-Enedioate置于水,Mercury(II) Trifluoroacetate,三氟乙酸体系中,用丙酮用作溶剂,化学反应 6.0H,反应生成弗斯特罗定富马酸酯
参考文献:Antimuscarinic Compound Having A Low Content Of Impurities
标题:Antimuscarinic Compound Having A Low Content Of Impurities
摘要:抗降解性较稳定的富马酸费索特啶,其制备方法以及富马酸费索特啶特定降解杂质的合成方法.