CAS: 71626-11-4; Benalaxyl

该化合物是一种系统性杀真菌剂,主要用于农业,以控制作物中的各种真菌疾病;它属于化物类,对低温温和某些根腐烂真菌等病原体特别有效;Benaxyl功能,阻止目标真菌合成脊髓灰质酸(RNA),从而干扰其生长和生殖;该化合物的特点是它对哺乳动物的毒性相对较低,在环境中的持久性也比较低,因此是综合虫害管理的首选;通常用作叶子喷雾或土壤处理,取决于作物和特定目标疾病;此外,Benalaxyl经常与其他杀菌剂结合使用,以提高功效和扩大疾病控制范围;其应用须遵守条例准则,以确保人类健康和环境的安全.

结构式图片

相似化合物

97716-85-3 98243-83-5 75541-63-8

欧盟法规

《欧盟PIC法规》统一分类与标签"欧盟管控危险化学品"ECHA物质欧盟农药活性物质ECHA物质OtherC&L通报工作场所安全标识要求REACH预注册废弃物危险特性清单

上下游产品

CAS号52888-49-0 2-((2,6-二甲基苯基)氨... | CAS号103-80-0 苯乙酰氯

合成工艺路线路线简述

  • 合成目标产物 Benalaxyl 主要起始原料 Methyl N-(2,6-Dimethylphenyl)-Dl-Alaninate And Phenylacetyl Chloride
  • (文献来源)合成步骤主要原料 Methyl N-(2,6-Dimethylphenyl)-Dl-Alaninate 和 Phenylacetyl Chloride
苯乙酰氯,N-(2,6-二甲基苯基)丙氨酸甲酯置于碳酸氢钠,水,Ligroin体系中,用 甲苯,N,N-二甲基甲酰胺 作为反应溶剂,化学反应 4.5H,以so Obtaining 26 G的收率获得产物苯霜灵
参考文献:Acyl Anilines Exerting A Fungicidal Action
标题:Acyl Anilines Exerting A Fungicidal Action
摘要:本文披露了具有以下公式的酰基苯胺:##str1## 其中r和r.Sup.1(彼此相同或不同)= H; Ch.Sub.3; C.Sub.2H.Sub.5; N.C.Sub.3H.Sub.7;--Ch.Sub.2--Ch.Dbd.Ch.Sub.2;--Ch.Dbd.Ch--Ch.Sub.3; R.Sup.3和r.Sup.4(彼此相同或不同)= H; 烷基c.Sub.1-C.Sub.3; 卤代甲基; Cl; F; Cn; O-烷基; S-烷基; 烷氧甲基; 或r.Sup.3和r.Sup.4一起是(ch.Sub.2.Dbd.)##str2## (r.Sup.9 =烷基c.Sub.1-C.Sub.3); Cn;--Ch(or.Sup.5).Sub.2(r.Sup.5 =烷基或烷基亚甲基); ##str3## (r.Sup.6和r.Sup.7 =h,烷基)`n = 0,1 Z =苯基,可选取取代基; ##str4## 而r.Sup.2 =h,Ch.Sub.3; M = 1,2; Y =炔基c.Sub.2-C.Sub.8; 苯基,可选取取代基; 苯乙酰; 呋喃基,噻吩基; 吡啶基; 含有2或3个杂原子的杂环基团,其中一个不同于氮; R.Sup.8 = Ch.Sub.3; 烷氧甲基; 卤代甲基; O-烷基.公式i的化合物具有高度的杀真菌活性和低毒性.

海关参考信息

专利信息


专利号:WO-2025056767-A1
优先权日:2023-09-15
标题 :Process for the preparation of enantiomerically enriched aliphatic amines
发明人:BOU HAMDAN FARHAN; GODINEAU EDOUARD; SMEJKAL TOMAS; DUMEUNIER RAPHAEL; BOUSSEMGHOUNE MOHAMED ABDELOUAHAB; BLUM MATHIAS
权利人:SYNGENTA CROP PROTECTION AG
摘要:The present invention relates to a process for the preparation of enantiomerically enriched cyclobutylamines of formula (I) from α-tertiary cyclobutanones and reacting said enantiomerically enriched cyclobutylamines to enantiomerically enriched cyclobutylamides. Such compounds are useful intermediates in the synthesis of microbiocidal thiazole compounds.

专利号:US-2016073631-A1
优先权日:2013-03-04
标 题 :Process for the preparation of dihydropyrrole derivatives
发明人:EL QACEMI MYRIEM; SMITS HELMARS; CASSAYRE JEROME YVES; MULHOLLAND NICHOLAS PHILLIP; RENOLD PETER; GODINEAU EDOUARD; PITTERNA THOMAS
权利人:SYNGENTA PARTICIPATIONS AG; SYNGENTA LTD
摘要:The present invention provides stereoselective processes for the preparation of compounds of formula (I) n n n n n n n n n n n n wherein n P is phenyl, naphthyl, a 6-membered heteroaryl group containing one or two nitrogen atoms as ring members, or a 10-membered bicyclic heteroaryl group containing one or two nitrogen atoms as ring members, and wherein the phenyl, naphthyl and heteroaryl groups are optionally substituted; n R 1 is chlorodifluoromethyl or trifluoromethyl; n R 2 is optionally substituted aryl or optionally substituted heteroaryl; n n is 0 or 1; n including the process comprising n (a-i) reacting a compound of formula II n n n n n n n n n n n n n n n n wherein P, R 1 and R 2 are as defined for the compound of formula I; n with nitromethane in the presence a chiral catalyst to give a compound of formula III n n n n n n n n n n n n n n n n wherein P, R 1 and R 2 are as defined for the compound of formula I; and n (a-ii) reductively cyclising the compound of formula III to give the compound of formula I. n n n n n The invention also provides intermediates useful for processes for the synthesis of compounds of formula (I).

专利号:US-9233920-B2
优先权日:2010-06-11
标题 :Process for the preparation of dihydropyrrole derivatives
发明人:EL QACEMI MYRIEM; SMITS HELMARS; CASSAYRE JEROME YVES; MULHOLLAND NICHOLAS PHILLIP; RENOLD PETER; GODINEAU EDOUARD; PITTERNA THOMAS
权利人:EL QACEMI MYRIEM; SMITS HELMARS; CASSAYRE JEROME YVES; MULHOLLAND NICHOLAS PHILLIP; RENOLD PETER; GODINEAU EDOUARD; PITTERNA THOMAS; SYNGENTA PARTICIPATIONS AG; SYNGENTA LTD
摘要:The present invention provides stereoselective processes for the preparation of compounds of formula (I) wherein P is phenyl, naphthyl, a 6-membered heteroaryl group containing one or two nitrogen atoms as ring members, or a 10-membered bicyclic heteroaryl group containing one or two nitrogen atoms as ring members, and wherein the phenyl, naphthyl and heteroaryl groups are optionally substituted; R 1 is chlorodifluoromethyl or trifluoromethyl; R 2 is optionally substituted aryl or optionally substituted heteroaryl; n is 0 or 1; including the process comprising (a-i) reacting a compound of formula II wherein P, R 1 and R 2 are as defined for the compound of formula I; with nitromethane in the presence a chiral catalyst to give a compound of formula III Wherein P, R 1 and R 2 are as defined for the compound of formula I; and (a-ii) reductively cyclizing the compound of formula III to give the compound of formula I. The invention also provides intermediates useful for processes for the synthesis of compounds of formula (I).

专利号:WO-2023089578-A1
优先权日:2021-11-22
标题:A synthesis process of iron-bearing compositions and possible additional essential elements
发明人:MORMILE SILVIA; GUSMEROLI MARILENA; ZANARDI GIAMPAOLO; BIANCHI DANIELE; COTROMINO MICHELE; SARGIOTTO CHIARA; LIGUORI RICCARDO
权利人:GOWAN CROP PROT LIMITED
摘要:A synthesis process of iron-bearing compositions and possible additional essential elements is described for treating nutritional deficiencies in plants, in particular for the prevention and treatment of physiological alterations or nutritional unbalances in plants due to the deficiency of iron and other essential elements, and the iron-bearing compositions and possibly further essential elements obtained with said process.

专利号:US-10906880-B2
优先权日:2016-01-26
标题:Kind of isothiazole oxime ether-containing strobilurin derivatives and its preparation methods and application
发明人:FAN ZHIJIN; CHEN LAI; GUO XIAOFENG; ZHU YUJIE; QIAN XIAOLIN; MA LIUYONG; ZHANG NAILOU; WANG HAIXIA; ZHANG ZHIMING; XU JINGHUA; SONG YINQI
权利人:UNIV NANKAI
摘要:The present invention is that provided a synthesis method of a series of isothiazole oxime ether containing strobilurin derivatives IV. The present invention relates to 3,4-dichloroisothiazolyl oxime ether strobilurin derivatives, and their chemical structural formula is as shown by IV. n n n n n n n n n n The invention discloses the structural formula of the above compound, the synthesis method and the use as an insecticide, a fungicide, an anti-plant virus agent, and an agriculturally acceptable auxiliary or synergist and a commercial insecticide. The use of a fungicide, an anti-plant virus agent and an acaricide in combination for controlling agricultural, forestry, horticultural plant pests, diseases, virus diseases and preparation methods.

专利号:US-9968097-B2
优先权日:2012-05-30
标题:Composition comprising a biological control agent and a fungicide selected from inhibitors of the lipid membrane synthesis, the melanine biosynthesis, the nucleic acid synthesis or the signal transduction
发明人:WACHENDORFF-NEUMANN ULRIKE; ANDERSCH WOLFRAM; STENZEL KLAUS; SPRINGER BERND
权利人:BAYER CROPSCIENCE AG
摘要:The present invention relates to a composition comprising at least one biological control agent. Furthermore, the present invention relates to the use of this composition as well as a method for reducing overall damage of plants and plant parts.
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主要参考文献


1: Wang X, Wang D, Zhou Z, Zhu W. Subacute oral toxicity assessment of benalaxyl in mice based on metabolomics methods. Chemosphere. 2018 Jan;191:373-380. doi: 10.1016/j.chemosphere.2017.10.085. Epub 2017 Oct 15. doi: 10.1016/j.envpol.2017.03.004. Epub 2017 Mar 10. doi: 10.1016/j.chemosphere.2016.11.091. Epub 2016 Nov 22. doi: 10.1002/chir.22589. Epub 2016 Mar 2. doi: 10.1016/j.envpol.2016.01.081. Epub 2016 Feb 10. doi: 10.1021/acs.jafc.5b01448. Epub 2015 May 26. doi: 10.1080/03601234.2014.929482. doi: 10.1016/j.pestbp.2013.11.004. Epub 2013 Dec 4. doi: 10.1021/jf4020125. Epub 2013 Sep 13. doi: 10.1016/j.yrtph.2016.12.006. Epub 2016 Dec 18. doi: 10.1080/03601234.2013.778631. Erratum in: J Environ Sci Health B. 2013;48(12):1121. doi: 10.1007/s00128-012-0847-9. Epub 2012 Oct 2. doi: 10.1016/j.chemosphere.2011.11.029. Epub 2011 Dec 9. doi: 10.1016/j.chroma.2010.12.116. Epub 2011 Jan 5. doi: 10.1002/chir.20879. doi: 10.1021/jf902420a.

合成参考文献


摘要:Farm Chemicals Handbook., -(C150), 1991
摘要:Proceedings-British Crop Protection Conference-Pests and Diseases., -(11), 1981
摘要:S109 | PARCEDC | List of 7074 potential endocrine disrupting compounds (EDCs) by PARC T4.2 | DOI:10.5281/zenodo.10944198
参考文献:10.1016/j.talanta.2007.08.033
摘要:Mayer-Helm B, Hofbauer L, Müller J. Method development for the determination of selected pesticides on tobacco by high-performance liquid chromatography-electrospray ionisation-tandem mass spectrometry. Talanta. 2008 Feb 15;74(5):1184–90. doi: 10.1016/j.talanta.2007.08.033.
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