CAS: 63216-49-9; Rel-(1R,2S)-2-((Tert-Butoxycarbonyl)Amino)Cyclohexane-1-Carboxylic Acid

该化合物是一种氨酸衍生物,其特点是环环结构,有助于其独特的立体化学和物理特性.乙氧碳基(Boc)组的存在为氨基组提供了保护,使其在peptide合成和其他有机反应中有用.该化合物一般在室温中处于固态,在极地有机溶剂中溶解,反映其功能组.箱酸味会传播酸性特征,使其得以参与各种化学反应,包括酯化和恐吓.根据(1R,2S)配置,其立体化学学在确定其生物活动和与其他分子的相互作用方面发挥着关键作用.

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430460-38-1 57266-57-6 57266-55-4

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    专利信息


    专利号:US-2023295613-A1
    优先权日:2020-02-14
    标 题:Long chain carbon and cyclic amino acids substrates for genetic code reprogramming
    发明人：JEWETT MICHAEL C; LEE JOONGOO; MOORE JEFFREY S; SCHWARZ KEVIN J
    权利人:UNIV NORTHWESTERN; UNIV ILLINOIS
    摘要:Abstract: Disclosed are methods, systems, components, and compositions for synthesis of sequence defined polymers. The methods, systems, components, and compositions may be utilized for incorporating novel substrates that include non-standard amino acid monomers and non-amino acid monomers into sequence defined polymers. As disclosed herein, the novel substrates may be utilized for acylation of tRNA via flexizyme catalyzed reactions. The tRNAs thus acylated with the novel substrates may be utilized in synthesis platforms for incorporating the novel substrates into a sequence defined polymer.

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    合成参考文献


    参考文献:10.1055/s-0036-1589527
    摘要:Balci M. Acyl Azides: Versatile Compounds in the Synthesis of Various Heterocycles. Synthesis. 2018 Feb 01;50(07):1373–401. doi: 10.1055/s-0036-1589527.
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