CAS: 6282-02-6; N-(Hydroxymethyl)Benzamide

上下游产品

formaldehyd benzamide triethylamine benzamideN-(phenylsulfenyl)methylbenzamideN-(piperidinomethyl)benzamide 2,5-bis-(benzoylamino-methyl)-selenophene N-(5-methyl-selenophen-2-ylmethyl)-benzamideN-(5-methyl-selenophen-2-ylmethyl)-benzamide 2,3-bis-(benzoylamino-methyl)-5-methyl-selenophene

苯甲酰胺置于聚合甲醛体系中,用84%的收率获得产物n-羟甲基苯甲酰胺
参考文献:Preparation Of 3-Chloromethyl-4-Alkyl-Nitrobenzene By Chloromethylation
标题:Preparation Of 3-Chloromethyl-4-Alkyl-Nitrobenzene By Chloromethylation
摘要:一种从相应的酰胺甲基衍生物通过磷酰氯或磷酰氯和惰性溶剂制备4-烷基-3-氯甲基硝基苯衍生物的方法.这个过程还涉及到3-氯甲基-4-烷基硝基苯,它们是有用的中间体,用于制备某些取代的2,6-二硝基苯胺类芽前除草剂.

专利信息

专利号:US-12428385-B2
优先权日:2022-05-19
标 题:Composition of a lipophilic agent for solution phase synthesis of biomolecules
发明人：LI YONGFU
权利人:LI YONGFU; BROTIDE CORE LLC
摘要:Disclosed is a lipophilic agent comprising a triazine core having lipophilic groups for organic synthesis. The lipophilic agent soluble in one system of solvent(s) wherein the lipophilic agent is participated in a chemical reaction but insoluble by adding a miscible poor solvent to change solution composition after the reaction completes. The lipophilic agent facilitates process improvement wherein practical operation only involves mixing with reactants in solution followed by precipitating with change of solution composition followed by filtering to obtain the precipitated solid, simplifying the purification by isolating the desired solid. The operation is reproducible along the progress in a multi-step synthesis, allowing pure intermediates and pure product as a solid to be rapidly obtained with ease and certainty. This invention can thus accelerate research and development of pharmaceutical biomolecules, representing a tremendous step forward for boosting productivity and greening chemical industry.

专利号:US-3560521-A
优先权日:1967-08-07
标题:Blocking groups for cysteine containing peptides
发明人：MILKOWSKI JOHN D; VEBER DANIEL F; HIRSCHMANN RALPH F
权利人:MERCK & CO INC
摘要:NOVEL PROTECTING GROUPS FOR PEPTIDES CONTAINING A CRYSTEINE RESIDUE. PROCESS FOR THE SYNTHESIS OF PEPTIDES CONTAINING A CYSTEINE RESIDUE WHEREIN THE MERCAPTO FUNCTION OF THE CYSTEINE RESIDUE IS PROTECTED BY A LABILE BLOCKING GROUP. NOVEL INTERMEDIATES USEFUL IN PEPTIDE SYNTHESIS.

专利号:US-3770822-A
优先权日:1967-08-07
标 题 :S-lower alkanoyl- and acetonyl-amino-methylcysteine
发明人：MILKOWSKI J; VEBER D; HIRSCHMANN R
权利人:MERCK & CO INC
摘要:NOVEL PROTECTING GROUPS FOR PEPTIDES CONTAINING A CYTEINE RESIDUE. PROCESS FOR THE SYNTHESIS OF PEPTIDES CONTAINING A CYSTEINE RESIDUE WHEREIN THE MERCAPTO FUNCTION OF THE CYSTEINE RESIDUE IS PROTECTED BY A LABILE BLOCKING GROUP. NOVEL INTERMEDIATES USEFUL IN PEPTIDE SYNTHESIS.

专利号:US-4038306-A
优先权日:1967-08-07
标题 :N-t-butoxycarbonyl-s-lower alkanoylamidomethyl-cysteine and p-nitrophenyl esters
发明人：MILKOWSKI JOHN D; VEBER DANIEL F; HIRSCHMANN RALPH F
权利人:MERCK & CO INC
摘要:Novel protecting groups for peptides containing a cysteine residue. Process for the synthesis of peptides containing a cysteine residue wherein the mercapto function of the cysteine residue is protected by an acetamidomethyl radical or other labile blocking group. Novel intermediates useful in peptide synthesis.

专利号:US-2023373936-A1
优先权日:2022-05-19
标题:Composition of a lipophilic agent for solution phase synthesis of biomolecules

专利号:EP-4526297-A2
优先权日:2022-05-19
标 题:Composition of a lipophilic agent for solution phase synthesis of biomolecules