CAS: 591-21-9; Hexahydro-M-Xylene

该化合物是一种含有分子式C8H16的环烷,其特征是1和3位置上两个甲基组的环己烷,该环己烷具有不对称性并影响其物理特性;该化合物在室温下是一种无色液体,具有一种特质的气味;相对非极性,在有机溶剂中溶解,但在水中溶解;与六氯环己烷相比,这些甲基组的存在导致其沸点较低,而且其挥发性更大;1,3-二甲基环己烷主要用作溶剂和有机合成;其化学稳定性使其得以进行各种反应,包括氢化和替代;此外,必须谨慎地处理这一化合物,因为它若吸入或摄入,可能会对健康造成危害;在实验室或工业环境中使用时,应当遵守适当的安全措施.

结构式图片

欧盟法规

ECHA物质ECHA物质C&L通报REACH预注册

上下游产品

3,5-dimethyl-2-cyclohexen-1-one ethene cyclohexane 2-ethyl-1-methylcyclopentane 1,2-di-m-tolylethane perfluoro-1,3-dimethylcyclohexane optically inactive 1.3-dimethyl-cyclohexanediol-(1.3) 1,3-dimethyl-1-nitro-cyclohexane Aliphatics, Saturated ( nitro acetate 4-(N,N-dimethylamino)-3-nitrobenzoic acid ethyl 4-(methylamino)-3-nitrobenzoate 4-dimethylamino-3-nitrobenzaldehyde ethyl 4-(methylamino)-3-nitrobenzoate 3-amino-4-(methylamino)benzoic acid 4-methylamino-3-nitro-benzoic acid chloride 3-amino-4-(methylamino)benzamide

合成工艺路线路线简述

    📜环辛烷置于三氯化铝体系中,化学反应生成 1,3-二甲基环己烷
    参考文献:Turowa-Poljak; Gurwitsch; Jegorowa,Zhurnal Obshchei Khimii,1947,Vol. 17,P. 137
    标题:Turowa-Poljak; Gurwitsch; Jegorowa,Zhurnal Obshchei Khimii,1947,Vol. 17,P. 137

    专利信息


    专利号:US-2003162992-A1
    优先权日:2001-12-14
    标 题 :Preparation of intermediates useful in the synthesis of antiviral nucleosides
    发明人:WATANABE KYOICHI A; DU JINFA
    摘要:The present invention is an efficient process for the manufacture of α-acyloxyacetaldehyde, a key intermediate in the synthesis of 1,3-oxathiolane and 1,3-dioxolane nucleosides.

    专利号:US-4049710-A
    优先权日:1976-02-24
    标题:Novel carbamimidoyl chlorides and their use in the synthesis of herbicidal triazinediones
    发明人:TOCKER STANLEY
    权利人:DU PONT
    摘要:Carbamimidoyl chlorides of the formula: WHERE R2 is alkyl of 1-4 carbon atoms are useful as intermediates in the synthesis of herbicidal triazinediones of the formula: where R1 is certain organic radicals.

    专利号:US-4197408-A
    优先权日:1975-08-01
    标 题 :Asymmetric synthesis of alkyl chrysanthemate
    发明人:ARATANI TADATOSHI; FUJITA FUMIO; NAGASE TSUNEYUKI; YONEYOSHI YUKIO
    权利人:SUMITOMO CHEMICAL CO
    摘要:A process for the production of an optically active chrysanthemate which comprises reacting 2,5-dimethyl-2,4-hexadiene with a diazoacetate of the formula: n n N.sub.2 CHCOOR n n wherein R is selected from the group consisting of (a) cycloalkyl group with or without substituent(s) whose total carbon atom number is 5-20, (b) tertiary aralkyl group whose carbon atom number is 9 to 20, and (c) tertiary alkyl group with or without alkoxy substituent(s) whose total carbon atom number is 4-20, in the presence of a copper complex coordinated with a chiral Schiff base of the formula: ##STR1## wherein C* is an asymmetric carbon atom, R 1 is selected from the group consisting of (a) alkyl groups whose carbon atom number is 1-10 and (b) aralkyl groups with or without alkoxy substituent(s), whose total carbon atom number is 7-20, R 2 is selected from aryl groups with alkoxy substituent(s), whose total carbon atom number is 7-30, and each of X 1 and X 2 is selected from the group consisting of (a) hydrogen atom, (b) alkyl groups having 1-10 carbon atoms, (c) phenyl group, (d) alkoxy groups having 1-10 carbon atoms, (e) halogen atoms and (f) nitro group, or (g) X 1 and X 2 together form a benzo group.

    专利号:US-6596884-B2
    优先权日:1998-06-29
    标 题:Synthesis of hydrogen peroxide
    发明人:BECKMAN ERIC J; HANCU DAN
    权利人:UNIV PITTSBURGH
    摘要:A method for synthesizing hydrogen peroxide comprises the steps of: synthesizing an analog of anthraquinone that is miscible or soluble in carbon dioxide; reacting the analog of anthraquinone with hydrogen in carbon dioxide to produce a corresponding analog of tetrahydroquinone; and reacting the analog of tetrahydroquinone with oxygen to produce the hydrogen peroxide and regenerate the analog of anthraquinone. A chemical compound having the formula: n wherein R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , and R 8 are independently, the same or different, H, R C , or R S R C , wherein R S is a spacer group and R C is a fluoroalkyl group, a fluoroether group, a silicone group, an alkylene oxide group, a fluorinated acrylate group, or a phosphazine group, and wherein at least one of R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , and R 8 is not H.

    专利号:US-6387893-B1
    优先权日:1999-09-30
    标题 :Spirotricyclic substituted azacycloalkane derivatives and uses thereof
    发明人:EVANS BEN E; HOFFMAN JACOB M; GILBERT KEVIN F; RITTLE KENNETH E
    权利人:MERCK & CO INC
    摘要:Spirotricyclic azacycloalkyl compounds and pharmaceutically acceptable salts thereof are disclosed. The synthesis of these compounds is also described. One application of these compounds, which are alpha 1a adrenergic receptor antagonists, is in the treatment of benign prostatic hyperplasia. These compounds are selective in their ability to relax smooth muscle tissue enriched in the alpha 1a receptor subtype without at the same time inducing hypotension. One such tissue is found surrounding the urethral lining. Therefore, one utility of the instant compounds is to provide acute relief to males suffering from benign prostatic hyperplasia, by permitting less hindered urine flow. Another utility of the instant compounds is provided by combination with a human 5-alpha reductase inhibitory compound, such that both acute and chronic relief from the effects of benign prostatic hyperplasia can be achieved.

    专利号:US-6326372-B1
    优先权日:1999-09-30
    标 题:Lactam and cyclic urea derivatives useful as alpha 1a adrenoceptor antagonists
    发明人:EVANS BEN E; GILBERT KEVIN F
    权利人:MERCK & CO INC
    摘要:Lactam and cyclic urea derivatives and their pharmaceutically acceptable salts are disclosed. The synthesis of these compounds and their use as alpha 1a adrenergic receptor antagonists is also described. One application of these compounds is in the treatment of benign prostatic hyperplasia. These compounds are typically selective in their ability to relax smooth muscle tissue enriched in the alpha 1a receptor subtype without at the same time inducing hypotension. One such tissue is found surrounding the urethral lining. Therefore, one utility of the instant compounds is to provide acute relief to males suffering from benign prostatic hyperplasia, by permitting less hindered urine flow. Another utility of the instant compounds is provided by combination with a human 5-alpha reductase inhibitory compound, such that both acute and chronic relief from the effects of benign prostatic hyperplasia can be achieved.

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:Dai, X.; Shi, F., Science of Synthesis: Catalytic Reduction in Organic Synthesis, (2017) 1, 148.
    摘要:Dai, X.; Shi, F., Science of Synthesis: Catalytic Reduction in Organic Synthesis, (2017) 1, 128.
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