CAS: 586-39-0; 1-Nitro-3-Vinylbenzene

上下游产品

4-(3-nitro-phenyl)-oxetan-2-one (E)-3-Nitr°Cinnamic acid acetic anhydride 3-nitro-benzaldehyde trans-2-(m-nitrophenyl)cyclopropanecarboxylic acid 3-vinylaniline N,N'-bis-(3-vinylphenyl)hydrazine N-oxidebis-(3-vinyl-phenyl)-diazene-N-oxide

📜间硝基肉桂酸置于ferulic Acid Decarboxylase From Saccharomyces Cerevisiae体系中,用 Aq. Phosphate Buffer,二甲基亚砜 作为反应溶剂,化学反应生成 3-硝基苯乙烯
参考文献:同位素效应和线性自由能关系探测新型含异戊酸基黄素的酶阿魏酸脱羧酶的机理
标题:同位素效应和线性自由能关系探测新型含异戊酸基黄素的酶阿魏酸脱羧酶的机理
摘要:来自酿酒酵母的阿魏酸脱羧酶使用新描述的异戊烯基黄素单核苷酸辅因子催化苯基丙烯酸的脱羧形成苯乙烯.已经提出了一种机制,涉及前所未有的将烯丙基黄素与底物的α═β键的1,3-偶极环加成,该底物的α3β键用于激活底物进行脱羧作用.我们测量了在苯基丙烯酸的α和β位置上的次级氘动力学同位素效应(kie)与溶剂氘kie的组合.溶剂kie在v Max / K M上为3.3,但在v Max上接近于1,表明质子转移到产物发生在速率确定步骤之前.二次kies是在α-和β-位置正常但在大小取决于反应是否h中进行变化2 O或d 2 O.在d 2 O,酶催化氘成苯乙烯的交换; 该反应取决于碳酸氢盐的存在.该观察结果暗示在产物质子化之后必须发生co 2释放.通过使用一系列对位和间位取代的苯基丙烯酸,从反应的线性自由能分析中获得了更多信息.对数(k Cat / K M)对于该反应与哈米特σ很好的相关性-参数用ρ=-0.39+/-0
DOI:10.1021/acs.Biochem.6B00170

专利信息

专利号:US-11512303-B2
优先权日:2017-05-27
标 题 :Engineered polypeptides and their applications in the synthesis of beta-hydroxy-alpha-amino acids
发明人：CHEN HAIBIN; BONG YONG KOY; XU QING; ZHOU AMENG; SHEN TIANRAN; YANG JIADONG; YANG ZHUHONG
权利人:ENZYMASTER NINGBO BIO ENG CO LTD
摘要:The present invention provides engineered polypeptides that are useful for the asymmetric synthesis of β-hydroxy-α-amino acids under industrial-relevant conditions. The engineered polypeptides disclosed in this invention were developed through directed evolution based on the ability of catalytic synthesis of (2S, 3R)-2-amino-3-hydroxy-3-(4-nitrophenyl) propanoic acid. The present disclosure also provides polynucleotides encoding engineered polypeptides, host cells capable of expressing engineered polypeptides, and methods of producing β-hydroxy-α-amino acids using engineered polypeptides. Compared to other processes of preparation, the use of the engineered polypeptides of the present invention for the preparation of β-hydroxy-α-amino acids results in high purity of the desired stereoisomers, mild reaction conditions, low pollution and low energy consumption. So, it has good industrial application prospects.

专利号:US-9403854-B2
优先权日:2001-03-30
标 题 :Cross-metathesis reaction of functionalized and substituted olefins using group 8 transition metal carbene complexes as metathesis catalysts
发明人：GRUBBS ROBERT H; CHATTERJEE ARNAB K; CHOI TAE-LIM; GOLDBERG STEVEN D; LOVE JENNIFER A; MORGAN JOHN P; SANDERS DANIEL P; SCHOLL MATTHIAS; TOSTE F DEAN; TRNKA TINA M
权利人:CALIFORNIA INST OF TECHN
摘要:The invention pertains to the use of Group 8 transition metal carbene complexes as catalysts for olefin cross-metathesis reactions. In particular, ruthenium and osmium alkylidene complexes substituted with an N-heterocyclic carbene ligand are used to catalyze cross-metathesis reactions to provide a variety of substituted and functionalized olefins, including phosphonate-substituted olefins, directly halogenated olefins, 1,1,2-trisubstituted olefins, and quaternary allylic olefins. The invention further provides a method for creating functional diversity using the aforementioned complexes to catalyze cross-metathesis reactions of a first olefinic reactant, which may or may not be substituted with a functional group, with each of a plurality of different olefinic reactants, which may or may not be substituted with functional groups, to give a plurality of structurally distinct olefinic products. The methodology of the invention is also useful in facilitating the stereoselective synthesis of 1,2-disubstituted olefins in the cis configuration.

专利号:US-2002001821-A1
优先权日:1994-02-10
标 题:Methods for direct synthesis of compounds having complementary structure to a desired molecular entity and use thereof

专利号:US-6127154-A
优先权日:1994-02-10
标题 :Methods for direct synthesis of compounds having complementary structure to a desired molecular entity and use thereof
发明人：MOSBACH KLAUS; CORMACK PETER A G; RAMSTROEM OLOF; HAUPT KARSTEN
摘要:Compounds which possess a complementary structure to a desired molecule, such as a biomolecule, in particular polymeric or oligomeric compounds, which are useful as in vivo or in vitro diagnostic and therapeutic agents are provided. Also, various methods for producing such compounds are provided. These polymeric or oligomeric compounds are useful in particular as antimicrobial agents, receptor, hormone or enzyme agonists and antagonists.

专利号:US-8263774-B2
优先权日:2009-09-03
标题:Quinoline-oxazoline compounds and their use in oxidation synthesis
发明人：SIGMAN MATTHEW SCOTT; MICHEL BRIAN WILLIAM
权利人:SIGMAN MATTHEW SCOTT; MICHEL BRIAN WILLIAM; UNIV UTAH RES FOUND
摘要:A quinoline-oxazoline compound having the formula: n n n n n n n n n n n n where one of X 1 and X 2 is N and the other is C and one of R1, R2 and R3 is Z wherein Z is an oxazoline radical having the formula n n n n n nsuch that when X 1 is N R2 is Z and R1 is absent, and when X 2 is N either R1 or R3 is Z and R2 is absent. R1 and R3 through R12 are independently H or a pendant moiety which does not interfere with coordination of either N in the quinoline compound with a coordination center. These compounds can be complexed with a suitable coordination center such as catalytically active palladium and can be highly useful in catalytically oxidizing alkenes with high regioselectivity.

专利号:US-10011664-B2
优先权日:2011-02-04
标 题:Functionalized nitrile rubbers and the production thereof
发明人：OBRECHT WERNER; JESCHKO JULIA MARIA; NUYKEN OSKAR; SCHNEIDER MARTIN
权利人:OBRECHT WERNER; JESCHKO JULIA MARIA; NUYKEN OSKAR; SCHNEIDER MARTIN; ARLANXEO DEUTSCHLAND GMBH
摘要:Provided are new functionalized nitrile rubbers, which may optionally also be in partially or wholly hydrogenated form, and also a process for preparing them by metathesis of nitrile rubbers in the presence of a metathesis catalyst and at least one functionalized allyl compound. The new functionalized nitrile rubbers are suitable for producing vulcanizable mixtures and allow the production of vulcanizates having very stable networks. Also made possible, in particular, is the synthesis of block copolymers.