CAS: 544-51-4; Mycomycin

📜5-(N-Methyl-Anilino)-Penta-2,4-Dienal 在 Aluminium Amalgam,硫酸,Sodium Methylate体系中,用 1,4-二氧六环,甲醇,乙醚作为反应溶剂,获得 Trans,Trans-Mycomycin (Trans,Trans-Trideca-3,5,7,8-Tetraen-10,12-Diin-1-Saeure)
参考文献:Bohlmann,F.; Sucrow,W.,Chemische Berichte,1964,Vol. 97,P. 1846-1856
标题:Bohlmann,F.; Sucrow,W.,Chemische Berichte,1964,Vol. 97,P. 1846-1856

专利信息

专利号:TW-201018725-A
优先权日:2008-11-07
标题 :Application of methanoarchaeal lysine 2,3-aminomutase genes in the synthesis of pharmacological active compounds

专利号:US-7354745-B2
优先权日:1998-10-29
标题 :Method for producing L-β-lysine
发明人：FREY PERRY A; RUZICKA FRANK J
权利人:WISCONSIN ALUMNI RES FOUND
摘要:Purified β-amino acids are of considerable interest in the preparation of pharmacologically active compounds. Although enantiomerically pure β-amino acids, such as L-β-lysine, can be produced by standard chemical synthesis, this traditional approach is time consuming, requires expensive starting materials, and results in a racemic mixture which must be purified further. However, DNA molecules encoding lysine 2,3-aminomutase can be used to prepare L-β-lysine by methods that avoid the pitfalls of chemical synthesis. In particular, L-β-lysine can be synthesized by cultures of host cells that express recombinant lysine 2,3-aminomutase. Alternatively, such recombinant host cells can provide a source for isolating quantities of lysine 2,3-aminomutase, which in turn, can be used to produce L-β-lysine in vitro.

专利号:US-2011207183-A1
优先权日:2008-04-30
标 题 :Production Process for Fine Chemicals Using Microorganisms with Reduced Isocitrate Dehydrogenase Activity
发明人：HEROLD ANDREA; SCHROEDER HARTWIG; JEONG WEOL KYU; KLOPPROGGE CORINNA; ZELDER OSKAR; HAEFNER STEFAN; RICHTER ULRIKE; BECKER JUDITH; WITTMANN CHRISTOPH
权利人:BASF SE
摘要:The present invention is directed to a method utilizing a microorganism with reduced isocitrate dehydrogenase activity for the production of fine chemicals. Said fine chemicals may be amino acids, monomers for polymer synthesis, sugars, lipids, oils, fatty acids or vitamins and are preferably amino acids of the aspartate family, especially methionine or lysine, or derivatives of said amino acids, especially cadaverine. Furthermore, the present invention relates to a recombinant microorganism having a reduced isocitrate dehydrogenase activity in comparison to the initial microorganism and the use of such microorganisms in producing fine chemicals such as aspartate family amino acids and their derivatives.

专利号:TW-I410493-B
优先权日:2008-11-07
标题 :Application of Methanophilic Lysine 2,3 - Amino - transposase Gene in Drug Synthesis

专利号:CN-119118898-A
优先权日:2024-09-10
标题:Fluorescent probe capable of detecting sulfur dioxide derivative and viscosity and synthesis method