CAS: 53636-70-7; 6-Methyl-2,3-Pyridinedicarboxylic Acid

相似化合物

187242-97-3 1806328-68-6 1289094-52-5

上下游产品

Dimethyl 6-Methylpyridine-2,3-Dicarboxylate 83640-40-8

8-羟基喹哪啶置于四氯化碳,硝酸体系中,化学反应生成 6-甲基-2,3-吡啶二羧酸
参考文献:853.聚氮杂萘.第四部分 1:3:5-和1:3:8-三氮杂萘的其他衍生物
标题:853.聚氮杂萘.第四部分 1:3:5-和1:3:8-三氮杂萘的其他衍生物
摘要:
DOI:10.1039/jr9560004433

专利信息

专利号:WO-2023086799-A1
优先权日:2021-11-09
标 题:Heterocyclic compounds as triggering receptor expressed on myeloid cells 2 agonists
发明人：HOUZE JONATHAN B; PANDYA BHAUMIK; KAPLAN ALAN P
权利人:VIGIL NEUROSCIENCE INC
摘要:The present disclosure provides compounds of Formula I, useful for the activation of Triggering Receptor Expressed on Myeloid Cells 2 ('TREM2'). This disclosure also provides pharmaceutical compositions comprising the compounds, uses of the compounds, and compositions for treatment of, for example, a neurodegenerative disorder. Further, the disclosure provides intermediates useful in the synthesis of compounds of Formula I.

专利号:CN-101781245-A
优先权日:2009-06-26
标题 :A new method for the synthesis of substituted pyridine-3-carboxylic acids and analogues

专利号:US-7879885-B2
优先权日:2004-03-24
标 题:Thioalkeneamides as transketolase inhibitors
发明人：BOYD STEVEN A; CONDROSKI KEVIN R; THOMAS ALLEN; GONZALES STEPHEN S; GUNAWARDANA INDRANI W; HUEROU YVAN LE; ROMOFF TODD T; SULLIVAN FRANCIS X
权利人:ARRAY BIOPHARMA INC
摘要:The present invention provides thioalkeneamides of formula (I) which are useful as transketolase inhibitors: wherein R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R a -R d , n and ring A are as defined herein. The present invention also provides pharmaceutical compositions comprising the compounds of formula (I). The invention provides methods for inhibiting transketolase activity, reducing cellular ribose-5-phosphate levels, inhibiting nucleic acid synthesis, inhibiting cell proliferation and tumor cell growth in vitro and in vivo, stimulating apoptosis in tumor cells and treating cancer by administering a compound of formula (I) or a pharmaceutical composition thereof.