📜尿素置于盐酸体系中,用 水 作为反应溶剂,化学反应 3.0H,反应生成 尿素 参考文献:Deep Eutectic Solvents As Attractive Media For Co2 Capture 标题:Deep Eutectic Solvents As Attractive Media For Co2 Capture 摘要:报道了一种具有高重量比容量的深共熔溶剂家族,用于co2捕集. DOI:10.1039/c5Gc02319J
专利号:US-5648537-A 优先权日:1995-01-24 标题 :Process for the synthesis of substituted carbodiimides 发明人:HUSSENET PATRICIA; LE GOFF PHILIPPE; SENNYEY GERARD 权利人:POUDRES & EXPLOSIFS STE NALE 摘要:The invention relates to a new process for the synthesis of a disubstituted carbodiimide, including a first stage of phosgenation of an N,N'-disubstituted urea in an organic solvent medium. n After this first stage ammonia is added to the reaction mixture without preliminary isolation of any intermediate compound. n The process is simple, relatively inexpensive and the yield is high. n Disubstituted carbodiimides are organic synthesis intermediates used especially in pharmaceutical chemistry as coupling agents in peptide synthesis.
专利号:US-9765083-B2 优先权日:2013-12-03 标 题 :Method for the synthesis of irinotecan 发明人:ZABUDKIN ALEXANDER; MATVIENKO VIKTOR 权利人:SYNBIAS PHARMA AG 摘要:The present invention relates to a method for the synthesis of 7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxycamptothecin (i.e. iriniotecan), comprising: (a) preparing 10-[4-(1-piperidino)-1-piperidino]carbonyloxycamptotecin; and (b) selectively ethylating the compound of step (a) at the 7-position, thus resulting in the preparation of 7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxycamptothecin. The present invention is further directed to the use of 10-[4-(1-piperidino)-1-piperidino]carbonyloxycamptothecin (i.e. 7-des-ethyl-irinotecan) as intermediate in a method for the synthesis of irinotecan as described.
专利号:US-2024309142-A1 优先权日:2023-03-17 标题 :Capped block copolymers, their synthesis, manufacture, and methods of use 发明人:MAN VICTOR FUK-PONG; LI XIAOJIN HARRY; CHEN YIQING; PU GANG; HUNT JR CLINTON 权利人:ECOLAB USA INC 摘要:This disclosure relates to capped block copolymers, preferably reverse block copolymers capped with a hydrophobic group. Preferred hydrophobic groups include benzyl groups and silyl groups. In a preferred embodiment, the reverse block copolymer has at least two arms, wherein each arm is capped with a hydrophobic group. The disclosure also provides for the synthesis of the capped block copolymers as well as methods of using the capped block copolymers for defoaming and antifoaming applications.
专利号:US-5198507-A 优先权日:1990-06-12 标题:Synthesis of amino acid-derived bioerodible polymers 发明人:KOHN JOACHIM B; PULAPURA SATISH K K 权利人:UNIV RUTGERS 摘要:Novel amino acid-derived polycarbonates and amino acid-derived diphenol compound starting materials from which the polycarbonates are polymerized. Polymer blends of the amino acid-derived polycarbonates with polyiminocarbonates prepared from identical amino acid-derived diphenol starting materials.
专利号:US-10450264-B2 优先权日:2015-07-10 标题 :Synthesis of non-cyclic amide and thioamide based ionic liquids 发明人:BRODERICK ERIN M; BUCHBINDER AVRAM M; BHATTACHARYYA ALAKANANDA 权利人:UOP LLC 摘要:Non-cyclic amide or thioamide based ionic liquids and methods of making them are disclosed. The non-cyclic amide or thioamide based ionic liquid comprises a cation and an anion and has the formula:
专利号:US-6495693-B2 优先权日:1996-11-22 标题:N-(aryl/heteroaryl) amino acid derivatives, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds 发明人:AUDIA JAMES E; FOLMER BEVERLY K; JOHN VARGHESE; LATIMER LEE H; NISSEN JEFFREY S; PORTER WARREN J; THORSETT EUGENE D; WU JING 权利人:ATHENA NEUROSCIENCES INC; LILLY CO ELI 摘要:Disclosed are compounds which inhibit beta-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits beta-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.