CAS: 4877-93-4; 2,2'-Dimethoxybiphenyl

该化合物是有机化合物,其特征是其联苯结构,其中两种甲氧联苯组(-OCH3)附在2号方位的芳香环上,通常在室内温度下为白色至非白色固体,以其在水中的溶解性相对较低而著称,但在乙醇和乙醇等有机溶剂中可溶解.该化合物具有芳香化合物的典型特性,包括稳定性和各种化学反应的可能性,如电益替代.2,2'-二甲基氧联苯通常用于有机合成,并可作为其他化学化合物生产的中间体.该化合物的应用可扩展至材料科学,特别是在开发有机电子装置方面,因为其电子特性.安全数据表明,与许多有机化合物一样,应谨慎处理,使用适当的个人防护设备避免吸入或皮肤接触.

结构式图片

上下游产品

7-bromo-benzo[1,3]dioxole-5-carbaldehyde 4-iodoanisol 2-bromoanisole 4-methoxyphenyl magnesium bromide 2,2'-dimethoxy-5,5'-dinitrobiphenyl 2,2'-dimethoxy-3,5'-dinitro-biphenyl 2,2,2',2'-tetraphenyl-2,2'-(6,6'-dimethoxy-biphenyl-3,3'-diyl)-di-acetic acid 2,2'-dihydroxybiphenyl

合成工艺路线路线简述

  • 合成目标产物 2,2'-Dimethoxybiphenyl 主要起始原料 2,2'-Biphenol And Dimethyl Carbonate
  • (文献来源)合成步骤主要原料 2,2'-Biphenol 和 Dimethyl Carbonate
📜2-Methoxyphenyldiazonium Tetrafluoroborate置于palladium Diacetate体系中,化学反应 1.0H,以90%的收率获得产物2,2'-二甲氧基联苯
参考文献:Pd(oac)2催化离子液体中苯二氮杂鎓盐的均偶联:对称联芳基的合成
标题:Pd(oac)2催化离子液体中苯二氮杂鎓盐的均偶联:对称联芳基的合成
摘要:据报道,通过催化量的pd(oac)2和易得的咪唑鎓离子液体(ils),无需氧化剂,配体,通过催化二氮杂zon鎓盐的均匀偶联,合成对称联芳基的文库的一种简便,高收率且简单的方法.,添加剂或挥发性溶剂.简单的产品分离和il的回收/再利用代表了该方法的其他优点.
DOI:10.1016/j.Tetlet.2015.12.108

海关参考信息

专利信息


专利号:WO-2025215126-A1
优先权日:2024-04-12
标题:Synthesis of vidofludimus and its calcium salt
发明人:VITT DANIEL; IGLICAR PETRA; GEGE CHRISTIAN; Mühler Andreas; KOHLHOF HELLA; GRÖPPEL MANFRED
权利人:IMMUNIC AG
摘要:The invention relates to the process of preparation of 2-fluoro-4-(3-methoxyphenyl)aniline (3) as an intermediate. Said intermediate 2-fluoro-4-(3-methoxyphenyl)aniline (3) is obtained in a Suzuki coupling reaction from (3-methoxyphenyl)boronic acid (1) and 4-bromo-2-fluoro-aniline (2). The invention further relates to the synthesis of vidofludimus (5) from said intermediate 2-fluoro-4-(3-methoxy-phenyl)aniline (3) and from 1-cyclopentene-1,2-dicarboxylic anhydride (4). The invention further relates to the synthesis of vidofludimus calcium (6) from said vidofludimus (5) and from a calcium salt, preferably Ca(OH)2.

专利号:WO-2025056767-A1
优先权日:2023-09-15
标题 :Process for the preparation of enantiomerically enriched aliphatic amines
发明人:BOU HAMDAN FARHAN; GODINEAU EDOUARD; SMEJKAL TOMAS; DUMEUNIER RAPHAEL; BOUSSEMGHOUNE MOHAMED ABDELOUAHAB; BLUM MATHIAS
权利人:SYNGENTA CROP PROTECTION AG
摘要:The present invention relates to a process for the preparation of enantiomerically enriched cyclobutylamines of formula (I) from α-tertiary cyclobutanones and reacting said enantiomerically enriched cyclobutylamines to enantiomerically enriched cyclobutylamides. Such compounds are useful intermediates in the synthesis of microbiocidal thiazole compounds.

专利号:US-2024409557-A1
优先权日:2023-05-09
标 题 :5,6-fused and 6,6-fused bicyclic alcohols and ethers and compositions for use as 15-prostaglandin dehydrogenase modulators
发明人:GREENMAN KEVIN LLOYD; PICKRELL ALEXANDER J; LI KEXUE; AMEGADZIE ALBERT K; WANG HUI-LING; WEIRES NICHOLAS ANTHONY; ALLEN JOHN G; BOURBEAU MATTHEW P
权利人:AMGEN INC
摘要:The present disclosure provides novel 15-hydroxy-prostaglandin dehydrogenase inhibitors, pharmaceutical compositions comprising such compounds, and methods of using such compounds and compositions in treating 15-hydroxy-prostaglandin dehydrogenase-mediated disease. Also provided are methods of making such compounds and intermediates thereof. The compounds have a general Formula (A).Further, the disclosure provides intermediates useful in the synthesis of compounds of Formula (A).

专利号:CN-102731370-A
优先权日:2012-07-13
标 题 :Preparation method of ionic liquid and method for catalyzing synthesis of biphenyl compounds using ionic liquid palladium carbon

专利号:US-9752084-B2
优先权日:2013-02-26
标题 :Block copolymers, synthesis and application as dehydrating and desalting of heavy crudes
发明人:FLORES OROPEZA EUGENIO ALEJANDRO; FLORES SANDOVAL CESAR ANDRES; REYES MARTINEZ REYNA; HERNANDEZ CORTEZ JOSE GONZALO; LOPEZ ORTEGA ALFONSO; CASTRO SOTELO LAURA VERONICA; ALVAREZ RAMIREZ FERNANDO; ESTRADA MARTINEZ ARQUIMEDES; VAZQUEZ MORENO FLAVIO SALVADOR
权利人:MEXICANO INST PETROL
摘要:The present invention is related to formulations consisting by block copolymers α,ω-di-aryl or alkyl sulfonates of poly(ethylene oxide) w -poly(propylene oxide)-poly(ethylene oxide) w of bis-ammonium and block copolymers α,ω-di-amine of poly(ethylene oxide) w -poly(propylene oxide)-poly(ethylene oxide) w , that are effective in the dewatering and desalting crude whose specific gravities are within the range of 14 to 23° API.

专利号:EP-4590663-A2
优先权日:2022-09-21
标题 :Synthesis of cyclopropane carboxylic acids

供应商参考报价(招募中)

品牌试剂参考报价(招募中)

📌 第三方产品分析报告

✅ COA系统入驻 | 共享模式

合成参考文献


摘要:Amatore, M.; Aubert, C.; Malacria, M.; Petit, M., Science of Synthesis Knowledge Updates, (2012) 3, 48.
摘要:Sumida, Y.; Ohmiya, H., Science of Synthesis Knowledge Updates, (2022) 3, 43.
摘要:Denmark, S.; Chang, W.-T. T., Science of Synthesis: Cross Coupling and Heck-Type Reactions, (2012) 1, 402.
摘要:Mateos-Gil, J.; Fa, Science of Synthesis: Knowledge Updates, (2024) 1, 197.
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