CAS: 38857-88-4; Bis(2,2,2-Trichloroethyl)Azodicarboxylate

该化合物是一种化学化合物,其独特的结构特征包括二氮功能组和二碳酸产生的两个酯组;该化合物因其氯化程度高而引人注目,特别是存在三氯乙基组,有助于其稳定性和反应性;二氮基存在,表明有可能发生各种化学反应,包括典型的亚氮化合物,如相交或热分解;该复合通常用于专门用途,包括作为有机合成的试剂或作为生产其他化学物质的中间体;其物理特性,如溶性和熔点,可因样品的具体条件和纯度而变化;安全考虑十分重要,因为氯原子的存在可能构成健康风险和环境关切;在与该化合物合作时,应遵循适当的处理和处置程序.

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1972-28-7 940868-64-4 2446-83-5

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CAS号38858-02-5 2,2,2-trichloro... | CAS号69496-46-4 2,4-dimethyl-(1...

合成工艺路线路线简述

    📜Bis(2,2,2-Trichloroethyl) Hydrazino-1,2-Dicarboxylate置于吡啶,溴体系中,用 二氯甲烷 作为反应溶剂,化学反应生成 偶氮基二羧酸双(2,2,2-三氯乙酯)
    参考文献:使用异羟肟酸对烯烃进行无金属氧化
    标题:使用异羟肟酸对烯烃进行无金属氧化
    摘要:描述了一种自由基介导的无金属烯烃氧胺化方法.该方法利用烯烃加成中脒氧基自由基的独特反应性,使用简单的偶氮二甲酸二异丙酯 (Diad) 作为自由基陷阱提供一般的双官能化.该协议利用该过程的分子内性质,在所有情况下提供单一区域异构体.环状烯烃的双官能化提供了使用当前方法无法获得的具有高立体选择性的反式氧胺化产物,补充了顺式选择性氧胺化过程.
    DOI:10.1021/ja204255E

    海关参考信息

    专利信息


    专利号:US-8138272-B2
    优先权日:2006-05-22
    标 题:Preparation of polymer conjugates of therapeutic, agricultural, and food additive compounds
    发明人:KONRADI ANDREI W; SMITH JENIFER L
    权利人:KONRADI ANDREI W; SMITH JENIFER L; ELAN PHARM INC
    摘要:This invention provides an improved synthesis of polymer conjugates of formula (I), n nof agricultural, therapeutic, and food additive compounds. In particular, a process is described for the preparation of conjugates by treating primary or secondary alcohol substituents of active compounds with polymeric nucleophiles using “Mitsunobuâ€? or related reaction conditions.

    专利号:WO-2023276983-A1
    优先权日:2021-06-28
    标题 :Synthesis intermediate for beraprost or optically active form thereof, and method for producing same
    发明人:AOYAGI SHIGENOBU; YAMADA RYO
    权利人:OUCHI SHINKO CHEMICAL IND CO LTD
    摘要:The present disclosure provides: a novel synthesis intermediate for beraprost or an optically active form thereof; and a production method using the synthesis intermediate. More specifically, in the present disclosure, a compound represented by general formula (I) or (II) or an optically active form thereof is used as a synthesis intermediate in the production of beraprost or an optically active form thereof.

    专利号:WO-2013065066-A1
    优先权日:2011-11-02
    标 题 :Processes for preparing 4-oxo-4-[3-(trifluoromethyl)-5,6- dihydro [l,2,41-triazolo[43-a]pyrazin-7(8h)-yl]-l-(2,4,5- trifluorophenyl)butan-2-amine
    发明人:PANDEY BIPIN; DAVE MAYANK GHANSHYAMBHAI; KOTHARI HIMANSHU M; SHUKLA BHAVIN SHRIPRASAD; MENDIRATTA SANJEEV KUMAR; JOSHI RUPAL; TRIVEDI UMANG
    权利人:CADILA HEALTHCARE LTD; PANDEY BIPIN; DAVE MAYANK GHANSHYAMBHAI; KOTHARI HIMANSHU M; SHUKLA BHAVIN SHRIPRASAD; MENDIRATTA SANJEEV KUMAR; JOSHI RUPAL; TRIVEDI UMANG
    摘要:The present invention relates to synthesis of 4-oxo-4-[3-(trifluoromethyl)-5,6- dihydro [l,2,4]-triazolo[4,3-a]pyrazin-7(8H)-yl]-l-(2,4,5-trifluorophenyl)butan-2- amine of Formula (I) either in its racemic (R/S) form or any of its optically active (S) or (R) forms or enantiomeric excess mixture of any of the forms by novel processes. The invention further relates to certain novel intermediates useful in the preparation of compound of Formula (I) and processes for their preparation.

    专利号:CN-118164894-A
    优先权日:2024-03-13
    标 题 :Synthesis method of 3-aminoindole compound

    专利号:CN-119331043-A
    优先权日:2024-10-17
    标题 :Synthesis method of steroid chiral amine

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    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献

    [参考文献]: Michael C Hillier, Et Al. Stereoselective Formation Of Carbon-Carbon Bonds Via Sn2-Displacement: Synthesis Of Substituted Cycloalkyl[参考文献]: Pompiliu S Aburel, Et Al. Catalytic And Enantioselective Aza-Ene And Hetero-Diels-Alder Reactions Of Alkenes And Dienes With Azodicarboxylates. Org Biomol Chem. 2005 Jun 21;3(12):2344-9.

    合成参考文献

    合成方法参考DOI号:10.1021/ol7022054
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