CAS: 24558-01-8; Levophacetoperane

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      专利号:US-10456387-B2
      优先权日:2011-11-29
      标 题:Phacetoperane for treating of attention deficit hyperactivity disorder
      发明人:KONOFAL ERIC; FIGADERE BRUNO
      权利人:NLS PHARMA AG; NLS PHARMACEUTICS AG
      摘要:The invention relates to the treatment of an attention deficit hyperactivity disorder (ADHD) with alpha-phenyl(piperidin-2-yl)methanol, or the pharmaceutically acceptable salts and esters thereof, in particular the acetate derivative, more particularly dextrophacetoperane. The invention additionally provides a method of synthesis of the (S,S) enantiomer of alpha-phenyl(piperidin-2-yl)methanol as well as a method of synthesis of dextrophacetoperane.

      专利号:US-2008214827-A1
      优先权日:2004-02-03
      标 题:Synthesis of Cyanoimino-Benzoimidazoles
      发明人:GOEHRING R RICHARD; WHITEHEAD JOHN; SHAO BIN
      权利人:EURO CELTIQUE SA
      摘要:Disclosed in certain embodiments is a process for synthesizing a compound of formula (V) and salts thereof.

      专利号:CA-2555219-A1
      优先权日:2004-02-03
      标 题 :Synthesis of cyanoimino-benzoimidazoles

      专利号:AU-2007300627-A1
      优先权日:2006-09-22
      标题:Method of treatment using fatty acid synthesis inhibitors

      专利号:AU-2007300627-B2
      优先权日:2006-09-22
      标题 :Method of treatment using fatty acid synthesis inhibitors

      专利号:CA-2664113-C
      优先权日:2006-09-22
      标 题:Use of platencin and platensimycin as fatty acid synthesis inhibitors to treat obesity, diabetes and cancer

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      主要参考文献


      1: SABBATINI F. [FOREIGN PSYCHOPHARMACOLOGICAL DRUGS: LEVOFACETOPERANE (8228 RP)]. Minerva Med. 1964 Oct 31;55:3473-6. Italian. French. French.

      合成参考文献


      参考文献:10.2174/0929867330666230120161837
      摘要:Konofal E, Lecendreux M, Bizot JC, Lormier AT, Figadère B. NLS-3 (Levophacetoperane or (R,R) Phacetoperane): A Reverse Ester of Methylphenidate: A Literature Review. Curr Med Chem. 2024;31(9):1069–81. doi: 10.2174/0929867330666230120161837.
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