CAS: 22384-63-0; 2-(3,4-Dihydroxyphenyl)-5,6-Dihydroxy-7-Methoxy-4H-Chromen-4-One

该化合物是属于菜菜类的化学化合物,具体来说,是一种花粉胶质,主要来自各种植物来源,特别是豆类家族中的植物来源.Pedalitin的特点是其甘蓝结构,通常包括一种与糖味相关的甘蓝.该产品展示了一系列生物活动,包括抗氧化特性,有助于其潜在的健康利益.此外,黄麻可能在植物防御机制中发挥作用,并已就其对人类健康的影响进行了研究,包括防炎和抗癌活动,其溶性与稳定性可因溶剂和环境条件而异.与许多花类相比,许多花粉,蓝盐的生物利用率和生物系统功效是正在进行的研究的主题,突出其在植物化学和药理学方面的重要性.

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CAS号25782-30-3 PEDALITINTETRAA...

合成工艺路线路线简述

    📜4'-Hydroxy-5,6,7,3'-Tetramethoxyflavone置于氢溴酸,溶剂黄146体系中,用45.3 %的收率获得胡麻黄素; 5,6,3',4'-四羟基-7-甲氧基黄酮
    参考文献:5,6,7,3',4'-单甲氧基四羟基黄酮的合成研究:Pedalitin 的合成
    标题:5,6,7,3',4'-单甲氧基四羟基黄酮的合成研究:Pedalitin 的合成
    摘要:在针对 5,6,7,3',4'-单甲氧基四羟基黄酮的合成研究中,实现了一种简洁的 Pedalitin 合成程序.如前所述,6-羟基-2,3,4-三甲氧基苯乙酮是通过 1,4-二羟基-2,6-二甲氧基苯与三氟化硼醚酸二乙酯在乙酸中酰化制备的.当在碱性条件下进行 6-羟基-2,3,4-三甲氧基苯乙酮 2B 与香兰素的羟醛缩合时,它产生了 2'-羟基查尔酮 3B,令人惊讶的是,它与 3-羟基黄酮 4 一起产生了相当数量的 3-羟基黄酮 4.我们提出这种氧化环化可能是由于醌化物的贡献,可能会受到有氧氧化.然后将查尔酮与碘在二甲基亚砜中进行氧化环化,得到产量非常好的黄酮 5.令我们高兴的是,在溴化氢溶液(30% 的乙酸溶液)下,3 个 5-,6-和 3'-位置的三个甲氧基的连续去甲基化顺利进行,产生 Pedalitin 1.3-羟基黄酮 4 和 Pedalitin Tetraacetate 6 的晶体结构通过
    Doi:10.3390/molecules29020513

    海关参考信息

    专利信息


    专利号:US-2007232495-A1
    优先权日:2006-03-24
    标题:Compositions and methods to add value to plant products, increasing the commercial quality, resistance to external factors and polyphenol content thereof
    发明人:NAPPA ALVARO O; LORENZINI FELIPE C; SANHUEZA ANDRES L
    权利人:NAPPA ALVARO O; LORENZINI FELIPE C; SANHUEZA ANDRES L
    摘要:The invention is related to compositions and methods that naturally protect plant tissues against ultraviolet radiation and temperature, thus giving protection against sunburn to plants, plant parts, fruits and/or flowers during their development. The invention is also related to compositions and methods to naturally improve the color of plants, plant parts, fruits and/or flowers by inducing the natural synthesis of flavonoids and anthocyanins present in plants. Likewise, the present invention is directed to improving the nutritional value of plants, plant parts, fruits and/or flowers by increasing the normal levels of polyphenolic compounds, especially flavonoids, present therein. Additionally, the present invention is related to compositions and methods that give more resistance to plants, plant parts, fruits and/or flowers against pathogens as bacteria and fungi. Finally, the present invention is related to plants, plant parts, fruits, flowers and/or propagating material treated with the compositions described in the present document.

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    合成参考文献


    参考文献:10.1007/s00253-018-9043-0
    摘要:Berim A, Gang DR. Production of methoxylated flavonoids in yeast using ring A hydroxylases and flavonoid O-methyltransferases from sweet basil. Applied Microbiology and Biotechnology. 2018 Apr 28;102(13):5585–98. doi: 10.1007/s00253-018-9043-0.
    参考文献:10.1186/s12870-021-03132-0
    摘要:Dossou SSK, Xu F, Cui X, Sheng C, Zhou R, You J, Tozo K, Wang L. Comparative metabolomics analysis of different sesame (Sesamum indicum L.) tissues reveals a tissue-specific accumulation of metabolites. BMC Plant Biology. 2021 Jul 24;21(1):352. doi: 10.1186/s12870-021-03132-0.
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