CAS: 22007-68-7; Isobutyrimidamide Hydrochloride

该化合物是一种有机化合物,其特征是其有矿功能组和一个分支的烷基结构,该物质具有丙胺酰胺脊柱,该物质附着于一个二甲基替代体,具有独特的特性,一般是无色的黄色液体或固体,视其纯度和形态而定,该化合物在有机合成和药用化学中的潜在用途而闻名,特别是作为各种药物的建筑块.该化合物的结构允许氢结合,它能够影响其溶解性和在不同溶剂中的再活性.此外,(1Z)-2-甲基丙胺酰胺可展示生物活动,使其与药物开发有关的研究感兴趣.在处理和储存时,应参考安全数据,与任何化学物质一样,以确保根据潜在毒性或再活性采取适当的预防措施.

结构式图片

相似化合物

18202-73-8 57297-29-7 57536-10-4

欧盟法规

ECHA物质C&L通报

上下游产品

Isobutyronitrile ethyl isobutyrimidate hydr°Chloride 2-Isopropyl-6-methyl-4(3H)-pyrimidone 4H11N3C4H11N3 4-(4-Fluoro-phenyl)-2,6-diisopropyl-1,4-dihydro-pyrimidine-5-carboxylic acid ethyl ester 3-Chloro-2-isopropyldiazirine

合成工艺路线路线简述

  • 合成目标产物 2-Methylpropanimidamide Hydrochloride 主要起始原料 Ethyl Isobutyrimidate Hydrochloride
  • (文献来源)合成步骤主要原料 Ethyl Isobutyrimidate Hydrochloride
📜异丁腈置于盐酸,氨体系中,用 甲醇,乙醚 用作溶剂,化学反应 2.0H,以30%的收率获得盐酸异丙基胍
参考文献:Ethylene Bis-Imidazoles Are Highly Potent And Selective Activators For Isozymes Va And Vii Of Carbonic Anhydrase,With A Potential Nootropic Effect
标题:Ethylene Bis-Imidazoles Are Highly Potent And Selective Activators For Isozymes Va And Vii Of Carbonic Anhydrase,With A Potential Nootropic Effect
摘要:乙烯双咪唑对参与脑生理的关键人类碳酸酐酶同工酶显示出纳摩尔级别的选择性和效力.
Doi:10.1039/c4Cc02346C

专利信息


专利号:US-6291620-B1
优先权日:1994-11-09
标 题:Polymer synthesis
发明人:MOAD GRAEME; MOAD CATHERINE LOUISE; KRSTINA JULIA; RIZZARDO EZIO; DARLING THOMAS ROBERT; BERGE CHARLES THOMAS
权利人:DU PONT; COMMW SCIENT IND RES ORG
摘要:Process for the synthesis of block polymers, homopolymers and copolymers of narrow polydispersity having formula (1) by contacting selected vinyl monomer(s), vinyl-terminated compound(s) and free radicals in which effective control of production of polymer is achieved by controlling the mole ratio of vinyl monomer(s), vinyl-terminated compound(s) and free radicals relative to one another; and polymers produced thereby

专利号:US-4310631-A
优先权日:1979-10-12
标题 :Synthesis of water soluble cross-linkers and their use in the manufacture of anionic polymers
发明人:MACDONALD RUSSELL J
权利人:IONICS
摘要:The reaction of glycidyl methacrylate (GMA) with an ionogenic methacrylate ester containing amine groups of the tertiary type such as dimethylaminoethyl methacrylate (DMAEMA) in the presence of an acidic water solution produces a new and novel water soluble, ionic, cross-linking, methacrylate bifunctional monomer wnhich is useful in the manufacture of anion exchange polymers while employing an aqueous solvent system.

专利号:US-4374720-A
优先权日:1980-12-13
标题:Synthesis of water soluble cross-linkers and their use in the manufacture of anionic polymers
发明人:MACDONALD RUSSELL J
权利人:IONICS
摘要:The reaction of glycidyl methacrylate (GMA) with an ionogenic methacrylate ester containing amine groups of the tertiary type such as dimethylaminoethyl methacrylate (DMAEMA) in the presence of an acidic water solution produces a new and novel water soluble, ionic, cross-linking, methacrylate bifunctional monomer which is useful in the manufacture of anion exchange polymers while employing an aqueous solvent system.

专利号:US-4275227-A
优先权日:1979-10-12
标 题:Synthesis of water soluble cross-linkers and their use in the manufacture of anionic polymers
发明人:MACDONALD RUSSELL J
权利人:IONICS
摘要:The reaction of glycidyl methacrylate (GMA) with an ionogenic methacrylate ester containing amine groups of the tertiary type such as dimethylaminoethyl methacrylate (DMAEMA) in the presence of an acidic water solution produces a new and novel water soluble, ionic, cross-linking, methacrylate bifunctional monomer which is useful in the manufacture of anion exchange polymers while employing an aqueous solvent system.

专利号:US-6316519-B1
优先权日:1997-02-19
标 题 :Molecular weight controlled polymers by photopolymerization
发明人:BERGE CHARLES THOMAS; DESOBRY VINCENT
权利人:DU PONT
摘要:Synthesis of linear acrylic polymers and copolymers having controlled molecular weight by the photoinitiated free radical polymerization of vinyl monomers in the presence of chain transfer agents to produce polymers useful in coating compositions and the like, including printing inks.

专利号:US-4374206-A
优先权日:1981-02-23
标 题 :Synthesis of base-stable aliphatic anion exchange polymers
发明人:MACDONALD RUSSEL J; HODGDON RUSSELL B
权利人:IONICS
摘要:Base stable aliphatic anion exchangers are produced by reacting a water soluble methacrylate ester quaternary amine monomer with a non-water soluble glycol dimethacrylate ester cross-linking monomer.

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合成参考文献


摘要:von Angerer, S., Science of Synthesis Knowledge Updates, (2011) 1, 188.
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