CAS: 16110-09-1; 2,5-Dichloropyridine

相似化合物

6515-09-9 16063-70-0 2402-77-9

上下游产品

CAS号624-28-2 2,5-二溴吡啶 | CAS号2808-86-8 2,3,4,5-四氯吡啶 | CAS号13473-01-3 5-氯-2-甲氧基吡啶 | CAS号1851-22-5 3-氯吡啶N-氧化物 | CAS号107-06-2 1,2-二氯乙烷 | CAS号55933-94-3 (3,5,6-三氯-2-吡啶)-肼 | CAS号55933-95-4 2,3,5-trichloro... | CAS号4214-79-3 5-氯-2-吡啶醇 | CAS号75-44-5 光气 | CAS号4214-78-2 5-chloro-1-meth... | CAS号10461-91-3 N-(5-chloropyri... | CAS号102830-80-8 6-chloro-2-(4-c... | CAS号405230-82-2 2,5-二氯-4-氨基吡啶 | CAS号40473-01-6 2-溴-5-氯吡啶 | CAS号40771-41-3 5-氯-2-巯基吡啶 | CAS号5552-44-3 2,5-吡啶二甲酸二乙酯 | CAS号128072-93-5 5-氯吡啶甲酸乙酯 | CAS号444120-94-9 2-氯-5-(4,4,5,5-... | CAS号444120-91-6 6-氯吡啶-3-硼酸 | CAS号942206-23-7 2,5-二氯-3-碘吡啶

2,3,4,5-四氯吡啶置于sodium Hydroxide,三乙胺,肼体系中,用 乙醇,水 用作溶剂,化学反应生成2,5-二氯吡啶
参考文献:Method For Preparing 2,5-Dihalo-And 2,5,6-Trihalopyridines
标题:Method For Preparing 2,5-Dihalo-And 2,5,6-Trihalopyridines
摘要:一种制备与下列化学式对应的2,5-二卤和2,5,6-三卤吡啶的方法:其中每个x分别代表氯,氟或溴,R代表氢,氯,氟或溴,包括在以下反应介质中,将其中一种化学式的卤酰肼吡啶与过量的水合碱金属氢氧化物反应:反应介质选自1至4个碳原子的低碳醇和2至4个碳原子的低碳基乙二醇.

专利信息

专利号:US-2018051042-A1
优先权日:2016-08-22
标题 :Methods for forming saturated (hetero)cyclic borylated hydrocarbons and related compounds
发明人：SMITH III MILTON R; SHANNON TIMOTHY M; MALECZKA JR ROBERT E; FORNWALD RYAN M
权利人:UNIV MICHIGAN STATE
摘要:The disclosure relates to methods for forming at least partially saturated cyclic and heterocyclic borylated hydrocarbons, as well as related compounds, which can be precursor compounds in the synthesis of any of a variety of pharmaceutical or medicinal compounds with a desired structure and/or stereochemistry for drug synthesis or drug candidate evaluation. The methods generally include reduction of an unsaturated cyclic or heterocyclic borylated hydrocarbon having a boron-containing substituent at an sp 2 -carbon, where such reduction converts the sp 2 -carbon to an sp 3 -carbon at the point of attachment of the boron-containing substituent. The methods can exhibit a selectivity for syn-addition during reduction, which can provide stereospecific products, such as when the unsaturated cyclic or heterocyclic reactant is multiply substituted with boron groups and/or other functional groups.

专利号:US-RE49500-E
优先权日:2004-05-14
标 题:Pyrrole inhibitors of ERK protein kinase, synthesis thereof and intermediates thereto
发明人：MARTINEZ BOTELLA GABRIEL; HALE MICHAEL; MALTAIS FRANCOIS; STRAUB JUDITH; TANG QING
权利人:VERTEX PHARMA
摘要:The present invention relates to compounds useful of inhibitors of protein kinases. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders.

专利号:US-6262268-B1
优先权日:1999-11-10
标 题 :Process and intermediates to a tetrahydro-[1,8]-naphthyridine
发明人：PALUCKI MICHAEL; HUGHES DAVID L; YANG CHUNHUA; YASUDA NOBUYOSHI
权利人:MERCK & CO INC
摘要:A novel process is provided for the preparation of 3-(5,6,7,8-tetrahydro-[1,8]-naphthyridin-2-yl)-propylamine which is useful in the synthesis of alphav integrin receptor antagonists. Also provided are useful intermediates obtained from the process.

专利号:MX-PA06013209-A
优先权日:2004-05-14
标 题:PIRROL COMPOUNDS AS INHIBITORS OF THE PROTEIN CINASA ERK, SYNTHESIS OF THE SAME AND INTERMEDIARIES OF THE SAME.

专利号:US-6706885-B2
优先权日:2001-06-06
标题:Process for preparing integrin antagonist intermediates
发明人：YASUDA NOBUYOSHI; PALUCKI MICHAEL; XIAO YI; HARTNER FREDERICK W; TAN LUSHI
权利人:MERCK & CO INC
摘要:A novel process is provided for the preparation of optionally protected 2,5-di-(3'-aminopropyl)-pyridines which are useful in the synthesis of alphav integrin receptor antagonists. Also provided are useful intermediates obtained from the process.

专利号:ES-2261696-T3
优先权日:2001-07-31
标 题:DERIVATIVES OF HETEROARILHETEROALQUILAMINAS AND ITS USE AS INHIBITORS OF THE SYNTHESIS OF NITRIC OXIDE.