CAS: 107-90-4; Butyrimidamide

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CAS号109-74-0 正丁腈 | CAS号924-74-3 O-ethyl butanet...

📜丁腈置于氨,溴化铵体系中,化学反应生成丁脒
参考文献:Preparation Of Amidine Salts By Reaction Of Nitriles With Ammonium Salts In The Presence Of Ammonia
标题:Preparation Of Amidine Salts By Reaction Of Nitriles With Ammonium Salts In The Presence Of Ammonia
摘要:
Doi:10.1021/jo01051A033

专利信息

专利号:US-2004092003-A1
优先权日:1997-03-19
标题:Multifunctional ceramic particles as solid supports for solid phase and combinatorial solid phase synthesis
发明人：BOSCHETTI EGISTO; KOCIS PETR
权利人:INVITROGEN CORP
摘要:Inert, thermally and mechanically stable porous ceramic solid phase supports for use in solid phase synthesis of molecules wherein the porous ceramic solid supports can be used under a wide variety of reaction conditions and in synthesis methods, including but not limited to organic, regular, multiple parallel, or combinatorial organic synthesis on a solid phase. Methods of using the porous ceramic solid supports for solid phase synthesis of molecules, for solid phase synthesis of polypeptides or peptidomimetics, for generating combinatorial libraries of linkers, and for combinatorial synthesis of compounds, including small molecules and aromatic and heteroaromatic compounds.

专利号:US-2003180804-A1
优先权日:2001-10-29
标题:Solid phase synthesis of chemical libraries
发明人：PRYOR KENT E; LEWIS RONALD D; BROWN JASON W
权利人:CORVAS INT INC
摘要:The present invention provides compounds and compound libraries that are useful as protease modulators. The compounds and compound libraries are preferably made using the methods of the present invention which utilize peptide synthesis and combinatorial chemistry methods on a solid phase.

专利号:US-5712407-A
优先权日:1997-01-14
标题 :Method for the preparation of alpha-chlorinated chloroformates
发明人：KREUTZBERGER CHARLES B; ESWARAKRISHNAN SEETHA; DAMLE SURESH B
权利人:PPG INDUSTRIES INC
摘要:Novel catalysts for the synthesis of a alpha-chlorinated chloroformate from an aldehyde and phosgene are described. The catalysts include alkyl substituted guanidines, hexasubstituted guanidinium chlorides, substituted biguanidinium chloride, phenyldialkyliminiumtetraalkylguanidinium chloride, dialkylimidazolinium tetraalkylguanidinium chloride, phenyltetraalkylamidinium chloride and N,N-dialkyl-N'-alkylpyrrolidinium chloride.

专利号:US-4443629-A
优先权日:1981-07-03
标 题 :Preparation of hydrazidines
发明人：BONSE GERHARD; SCHMIDT THOMAS
权利人:BAYER AG
摘要:A one-step process for the preparation of hydrazidines of the general formula (I) in which R represents an optionally substituted alkyl group, an optionally substituted cycloalkyl group, an optionally substituted aryl group or an optionally substituted aralkyl group, or their acid addition salts, in high yield, comprises reacting appropriate amidines or their acid addition salts with hydrazine in solvents at reduced pressure and at temperatures between -80 DEG C. and +100 DEG C., the reaction being effected in the presence of water present in the solvent and/or in the hydrazine by employing it as hydrazine hydrate. The hydrazidines of formula (I) and their salts are valuable intermediates in heterocyclic chemistry, for example for the synthesis of herbicidally active as-triazinones.

专利号:US-12286405-B2
优先权日:2019-05-17
标题 :Scalable synthesis of dual-target inhibitor of cannabinoid-1 receptor and inducible nitric oxide synthase
发明人：ALIMARDANOV ASAF RAGIM; HUANG JUNFENG
权利人:US HEALTH
摘要:A process for the preparation of racemic and optically active (1E,NE)-N-(1-aminoethylidene)-3-(4-chlorophenyl)-4-phenyl-N′-((4-(trifluoromethyl)phenyl)sulfonyl)-4,5-dihydro-1H-pyrazole-1-carboximidamide in high enantiomerical purity is provided.

专利号:US-6040440-A
优先权日:1998-03-06
标题:Hypophosphite deoxygenation reactions in the synthesis of erythromycin derivatives
发明人：GRAHAM ALEXANDRA E; THOMAS ALBERT V; YANG RACHEL R P
权利人:ABBOTT LAB
摘要:A process for the preparation of 4''-deoxyerythromycins, having the formula: wherein R is H or OH, R1 is H or loweralkyl, and R2 is H or CH3 by treatment of the starting material, 2'-O-acetyl-4''-imidazolylthiocarbamoyl-erythromycin, with a hypophosphite reagent, in a water-miscible protic solvent optionally comprising a phase transfer agent. In a preferred embodiment, the water-miscible solvent is an alcohol and the starting material is reacted with sodium hypophosphite, ACVA and tetra-n-butylammonium hydroxide.