CAS: 96345-79-8; (2R,3S,4S,5S,6R)-2-(Hydroxymethyl)-6-(4-Isothiocyanatophenoxy)Tetrahydro-2H-Pyran-3,4,5-Triol
该化合物是一种合成甘油衍生物,具有异硫氰酸盐功能组,能够对蛋白质或peptides等含有地雷的分子进行共价共聚.该化合物在研究碳水化合物-蛋白质相互作用,电荷结合和细胞表面标签的基因生物学研究中特别有用.α-D-曼诺皮拉诺派仿造含有天然曼诺糖的甘油,而异硫氰酸盐组则在温和条件下确保稳定的硫素联系形成.其高纯度和再活性使其适合精确的生物分子标签应用.该产品通常用于开发甘油阵列,亲和诊断工具,为研究人员提供可靠的试剂,用于对人肉色特定确认系统.
- 英文名称(2R,3S,4S,5S,6R)-2-(Hydroxymethyl)-6-(4-Isothiocyanatophenoxy)Tetrahydro-2H-Pyran-3,4,5-Triol
- 中文名称4-异硫氰酸根合苯基α-D-吡喃甘露糖苷
- IUPAC名称(2R,3S,4S,5S,6R)-2-(hydroxymethyl)-6-(4-isothiocyanatophenoxy)tetrahydro-2H-pyran-3,4,5-triol
- 其它别名4-异硫氢酸苯基-α-D-甘露糖苷; (2R,3S,4S,5S,6R)-2-(羟甲基)-6-(4-异硫氰酸苯氧基)四氢-2H-吡喃-3,4,5-三醇
- CAS编号96345-79-8
- MFCD编号:MFCD00070374
- 分子式:C13H15NO6S分子量:313.33
- 产品CID: 2017136
- 产品分类有机原料→分子砌块→芳环类化合物→苯类化合物
物理性质
MSDS等安全信息
上下游产品
O-acetyl-ξ-D-glucopyranoside)(4-isothi°Cyanato-phenyl)-(tetra-O-acetyl-ξ-D-glucopyranoside) 4-hydroxyphenyl isothi°Cyanate 4-amino-phenol thiophosgene N-{20-[p-(α-D-mannopyranosyloxy)-phenylthioureidohexaethyleneglycolyl]-1H-[1,2,3]-triazole-4-yl-methyl}-11-thioacetyl-undecanoic acid amide bis-{N-[20-p-(α-D-mannopyranosyloxy)phenylthioureidohexaethyleneglycolyl]-1H-[1,2,3]-triazole-4-yl-methyl}-11,11′-disulphanediyl diundecanoic acid diamide合成工艺路线路线简述
- 合成目标产物 4-Isothiocyanatophenyl α-D-Mannopyranoside 主要起始原料 4-Nitrophenyl-Alpha-D-Mannopyranoside
- 34213-86-0 = 96345-79-8 [标题:Reaction Conditions
标题:Synthesis And Characterization Of Poly(Ethylene Oxide)-Block-Poly(Methylidene Malonate 2.1.2) Block Copolymers Bearing A Mannose Group At The Peo Chain End
作者:Studer,Peggy; Limal,David; Breton,Pascal; Riess,Gerard
参考文献:Bioconjugate Chemistry 日期:2005 卷标:16(1) 页码:223-229]
34213-86-0 = 96345-79-8
反应条件:1.1 Solvents: Ethanol,Water; 10 Min,Rt
标题:Mannose Functionalization Of A Sixth Generation Dendrimer
作者:Woller,Eric K.; Cloninger,Mary J.
参考文献:Biomacromolecules 日期:2001 卷标:2(3) 页码:1052-1054]
107-21-1 + 96345-79-8 + 9005-25-8 = 96345-79-8
反应条件:1.1 Solvents: Dimethyl Sulfoxide,Water; 20 H,Ph 9,Rt
标题:(Oligo)Mannose Functionalized Hydroxyethyl Starch Nanocapsules: En Route To Drug Delivery Systems With Targeting Properties
作者:Freichels,Helene; Wagner,Manfred; Okwieka,Patricia; Meyer,Ralf Georg; Mailaender,Volker; Et Al
参考文献:Journal Of Materials Chemistry B: Materials For Biology And Medicine 日期:2013 卷标:1(34) 页码:4338-4348]
= 96345-79-8 [标题:Reaction Conditions
标题:Bioinspired Ph-Responsive Polymers For The Intracellular Delivery Of Biomolecular Drugs
作者:Murthy,Niren; Campbell,Jean; Fausto,Nelson; Hoffman,Allan S.; Stayton,Patrick S.
参考文献:Bioconjugate Chemistry 日期:2003 卷标:14(2) 页码:412-419]
96345-79-8 + 1447667-36-8 = 96345-79-8
反应条件:1.1 Reagents: Sodium Carbonate Solvents: Water; 12 H,Ph 9.0,Rt
标题:Novel Monodisperse Pegtide Dendrons: Design,Fabrication,And Evaluation Of Mannose Receptor-Mediated Macrophage Targeting
作者:Gao,Jieming; Chen,Peiming; Singh,Yashveer; Zhang,Xiaoping; Szekely,Zoltan; Et Al
参考文献:Bioconjugate Chemistry 日期:2013 卷标:24(8) 页码:1332-1344]
= 96345-79-8 [标题:Reaction Conditions
标题:Glycodendrimer Synthesis Without Using Protecting Groups
作者:Kieburg,Christoffer; Lindhorst,Thisbe K.
参考文献:Tetrahedron Letters 日期:1997 卷标:38(22) 页码:3885-3888]
= 96345-79-8 [标题:Reaction Conditions
标题:Manufacture Of Glycosylated Insulin For Diabetes Treatment
参考文献:Japan
📜对硝基苯-Alpha-D-吡喃甘露糖苷置于red. Agent体系中,用 水 作为反应溶剂,化学反应生成 4-异硫氢酸苯基-α-D-甘露糖苷
参考文献:Glycodendrimer Synthesis Without Using Protecting Groups
标题:Glycodendrimer Synthesis Without Using Protecting Groups
摘要:Oligoantennary Neoglycoconjugates Can Act As Powerful Inhibitors Of Carbohydrate-Protein Interactions And Thus Serve As Antiadhesives In Carbohydrate-Based Adhesion Systems. They Were Obtained By A Procedure That Doesn'T Require Protecting Groups. Various Unprotected Ncs-Functionalized Saccharides Were Coupled With Oligoamines In Aqueous Solution. This Versatile Method Is Generally Applicable To The Synthesis Of Thiourea-Bridged Glycodendrimers. (C) 1997 Elsevier Science Ltd.
DOI:10.1016/s0040-4039(97)00760-0
海关参考信息
- 2905122000-异丙醇
2905310000-1,2-乙二醇
2905320000-1,2-丙二醇
2905399001-1,3-丙二醇 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
[参考文献]: Lamptey Rnl, Et, Al. Synthesis And Characterization Of Fatty Acid Grafted Chitosan Polymeric Micelles For Improved Gene Delivery Of Vgf To The Brain Through Intranasal Route. Biomedicines. 2022 Feb 19;10(2):493.[参考文献]: M Monsigny, Et Al. Uptake Of Neoglycoproteins Via Membrane Lectin(S) Of L1210 Cells Evidenced By Quantitative Flow Cytofluorometry And Drug Targeting. Biol Cell. 1984;51(2):187-96.
合成参考文献
参考文献:10.1007/978-981-97-4379-7_15
摘要:Harirchi P, Bastani K, Sakhaee K, Zahedi P. Molecularly Imprinted Polymers as Artificial Antibodies in Therapeutic Applications. 2024. In: Molecularly Imprinted Polymers: Path to Artificial Antibodies.
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