CAS: 681136-29-8; Jnj-1661010

上下游产品

1-(3-phenyl-[1,2,4]thiadiazol-5-yl)piperazine phenyl is°Cyanate 4-(3-Chloro-[1,2,4]thiadiazol-5-yl)-piperazine-1-carboxylic acid phenylamide phenylboronic acid

📜4-(3-Chloro-[1,2,4]Thiadiazol-5-yl)-Piperazine-1-Carboxylic Acid Phenylamide,苯硼酸 反应生成 N-苯基-4-(3-苯基-1,2,4-噻二唑-5-基)-1-哌嗪甲酰胺
参考文献:N-Heteroarylpiperazinyl Ureas As Modulators Of Fatty Acid Amide Hydrolase
标题:N-Heteroarylpiperazinyl Ureas As Modulators Of Fatty Acid Amide Hydrolase
摘要:描述了某些n-杂环芳基哌嗪基脲化合物,这些化合物可用作faah抑制剂.这些化合物可以用于制备药物组合物,并用于治疗由脂肪酰胺水解酶(Faah)活性介导的疾病状态,紊乱和情况的方法.因此,这些化合物可以用于治疗焦虑,疼痛,炎症,睡眠障碍,进食障碍或运动障碍(如多发性硬化症).

专利信息

专利号:US-12194020-B2
优先权日:2017-12-22
标 题:Reversing baldness through cannabinoid receptor activation
发明人：POSTREL RICHARD
权利人:POSTREL RICHARD
摘要:This invention reverses male pattern baldness by shocking dormant hair follicles out of their androgen induced hibernation phase back to the active hair-growing anagenic phase. The invention integrates two functions: 1) It blocks synthesis of compounds holding the follicles in the telogenic/hibernating phase and 2) It stimulates synthesis of compounds animating the hair-growing/anagenic phase in the follicular activity cycle. One preferred embodiment comprises an enzyme inhibitor blocking the conversion of testosterone to dihydrotestosterone (DHT), a flavonoid simultaneously increasing synthesis of prostaglandins alternative to prostaglandin D2, and a selected cannabinoid compound stimulating restore the hair follicle to its normal growth cycle. This novel trimodal therapy restores the hair follicles to their normal cycling processes and maintains these restorative properties so long as this rebalance in maintained.