CAS: 5509-65-9; 2,6-Difluoroaniline

上下游产品

2,6-difluorobenzoic acid 1-chloro-3,5-difluorobenzene 1-chloro-2,6-difluorobenzene 2-azido-1,3-difluorobenzene 2,2',6,6'-tetrafluoroazoxybenzene nted N-(2,6-difluorophenyl)formamide 2,6-difluorophenylisothi°Cyanate

三氯苯置于copper(I) Oxide Ammonium Hydroxide,Cesium Fluoride体系中,用 Various Solvent(S) 作为反应溶剂,化学反应 36.0H,反应生成 2,6-二氟苯胺
参考文献:Aromatic Fluorine Chemistry. Part 5. Preparation Of 2,6-Difluoroaniline And 1,2-Difluorobenzene
标题:Aromatic Fluorine Chemistry. Part 5. Preparation Of 2,6-Difluoroaniline And 1,2-Difluorobenzene
摘要:The Preparation Of 2,6-Difluoroaniline And 1,2-Difluorobenzene From 1,2,3-Trichlorobenzene Is Described. An Isomeric Mixture Of 1-Chloro-2,3-Difluorobenzene And 2-Chloro-1,3-Difluorobenzene Is Obtained From Kf Exchange On 1,2,3-Trichlorobenzene. Selective Dechlorination Of 1-Chloro-2,3-Difluorobenzene With H-2 And Pd/c Catalyst Gives 1,2-Difluorobenzene. 2,6-Difluoroaniline Is Obtained Via Ammonolysis Of 2-Chloro-1,3-Difluorobenzene.
DOI:10.1016/s0022-1139(00)80961-6

专利信息

专利号:WO-2025030970-A1
优先权日:2023-08-04
标 题:Condensing agent and use thereof in preparation of isothiocyanate
发明人：SI XIAOJIA; CHEN QUAN; LEI AIWEN; YI HONG; CHEN YI-HUNG
权利人:HUAWEI TECH CO LTD
摘要:The present application relates to the field of organic synthesis. Provided is a condensing agent. The condensing agent has formula 1, wherein R1 and R2 are each independently selected from the same or different electron-withdrawing groups. Compared with thiophosgene or carbon disulfide used in a traditional solution, the condensing agent provided in the embodiments of the present application has lower toxicity, and the condensing agent is a solid, such that the diffusion of pollution is easily controlled. Therefore, the condensing agent provided in the embodiments of the present application can be used for environmentally friendly synthesis of an isothiocyanate compound and has relatively small influence on the environment. Moreover, the condensing agent provided in the embodiments of the present application comprises electron-withdrawing groups, such that the yield of the isothiocyanate compound can be increased.

专利号:US-9549917-B2
优先权日:2011-09-08
标 题 :Heterocyclic-substituted benzofuran derivatives and methods of use thereof for the treatment of viral diseases
发明人：MCCOMAS CASEY C; LIVERTON NIGEL J; HABERMANN JOERG; KOCH UWE; NARJES FRANK; LI PENG; PENG XUANJIA; SOLL RICHARD; WU HAO; PALANI ANANDAN; DAI XING; LIU HONG; HE SHUWEN; LAI ZHONG; DANG QUN; ZORN NICOLAS
权利人:MCCOMAS CASEY C; LIVERTON NIGEL J; HABERMANN JOERG; KOCH UWE; NARJES FRANK; LI PENG; PENG XUANJIA; SOLL RICHARD; WU HAO; PALANI ANANDAN; DAI XING; LIU HONG; HE SHUWEN; LAI ZHONG; DANG QUN; ZORN NICOLAS; MERCK SHARP & DOHME
摘要:The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5B polymerase inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5B polymerase activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.

专利号:US-4272507-A
优先权日:1978-05-24
标 题:Phenylaminothiophenacetic acids, their synthesis, compositions and use
发明人：FIGALA VOLKER
权利人:BYK GULDEN LOMBERG CHEM FAB
摘要:Phenylaminothiophenacetic acids of formula I (I) wherein R1 denotes a hydrogen atom, a chlorine atom, a bromine atom or a methyl group, R2 denotes a -CH2-COOH group or a -CH2-COOR6 group, R3 denotes a hydrogen atom, a halogen atom, an alkyl group, an alkoxy group or a trifluoromethyl group, R4 has one of the meanings of R3, R5 denotes a hydrogen atom, a halogen atom or an alkyl group, R6 denotes an alkyl group (with from 1 to 5 carbon atoms), which is optionally substituted by hydroxyl, hydroxyalkoxy or alkanoyloxy groups, or a benzyl group and n denotes 1 or 2, and salts of the acids have outstanding antiphlogistic, analgesic and antipyretic activities.

专利号:US-10857530-B2
优先权日:2015-12-10
标题 :Olefin metathesis catalysts
发明人：JOHNS ADAM M; MONTGOMERY T PATRICK; AHMED TONIA S; GRUBBS ROBERT H; PEDERSON RICHARD L
权利人:UMICORE AG & CO KG; CALIFORNIA INST OF TECHN
摘要:This invention relates generally to metathesis catalysts and the use of such catalysts in the metathesis of olefins and olefin compounds, more particularly, in the use of such catalysts in Z and E selective olefin metathesis reactions. The invention has utility in the fields of organometallics and organic synthesis.

专利号:CN-114959752-A
优先权日:2022-04-29
标题:Electrochemical reactor, system and application in electrolytic synthesis of 2,6-dichlorobenzonitrile

专利号:US-7439382-B2
优先权日:2002-05-17
标题 :4-alkyl-2-haloaniline derivatives and process for producing the same
发明人：NISHIZUKA TOSHIO; KURIHARA HIROSHI
权利人:MEIJI SEIKA KAISHA
摘要:The present invention relates to a compound of formula (1), wherein R 1 , R 2 , R 3 , n, and X are as defined in the specification, and a process for producing the same. This compound is useful as an intermediate for the synthesis of compounds useful as pharmaceuticals or agricultural chemicals.