CAS: 4493-18-9; (2S,5R,6R)-6-Hexanamido-3,3-Dimethyl-7-Oxo-4-Thia-1-Azabicyclo[3.2.0]Heptane-2-Carboxylic Acid

英文名称(2S,5R,6R)-6-Hexanamido-3,3-Dimethyl-7-Oxo-4-Thia-1-Azabicyclo[3.2.0]Heptane-2-Carboxylic Acid
中文名称6a-[(1-氧代己基)氨基]青霉烷酸
IUPAC名称(2S,5R,6R)-6-hexanamido-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
其它别名6α-[(1-Oxohexyl)Amino]Penicillanic Acid; Dihydropenicillin F; Amylpenicillin; Dihydropenicillin Fq: What Is Dihydropenicillin F Q: What Is The Cas Number Of Dihydropenicillin F; Penicillin Impurity H; Benzylpenicillin Impurity 8 Monomer (Benzylpenicillin Ep Impurity H Monomer)
CAS编号4493-18-9
FDA UNII编号:2891Q2PTF9
分子式:C14H22N2O4S分子量:314.41
产品CID: 1455534
产品分类有机原料 → 有机酸及其衍生物 → 羧酸及其衍生物

相似结构搜索
产品信息参考
InChIKey: ACAZKHULUUVWCY-JFGNBEQYSA-N
InChI=1S/C14H22N2O4S/c1-4-5-6-7-8(17)15-9-11(18)16-10(13(19)20)14(2,3)21-12(9)16/h9-10,12H,4-7H2,1-3H3,(H,15,17)(H,19,20)/t9-,10+,12-/m1/s1
计算化学: 氢键受体数5.0氢键供体数2.0可旋转键数6.0

物理性质

沸点593.1°C at 760 mmHg
闪点312.5°C
密度1.3
PSA:86.71
LogP:2.4
折射率1.579
外观形态固体-粉末
储存条件Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
产品应用该化合物用于描述来自铬化铬的苯乙酸-COA离子酶.

MSDS等安全信息

警示词Warning

合成工艺路线路线简述

📜Alkaline Earth Salt Of/the/ Methylsulfuric Acid置于水,铂体系中,化学反应生成 6A-[(1-氧代己基)氨基]青霉烷酸
参考文献:Cook; Heilbron,Chemistry Of Penicillin
标题:Cook; Heilbron,Chemistry Of Penicillin

海关参考信息

2905121000-正丙醇
2905130000-正丁醇
2912110000-甲醛
2912120000-乙醛
💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
详情请参考：📖 海关编码查询和海关进出口税则

专利信息

专利号:CN-115925790-A
优先权日:2016-03-23
标题:Method for the synthesis of Î±4Î²7 peptide antagonists

其他信息查阅

供应商参考报价(招募中)

品牌试剂参考报价(招募中)

实用工具

📌 第三方产品分析报告

✅ COA系统入驻 | 共享模式

主要参考文献

1: Lopes-Júnior R, de Sá Del Fiol F, Araujo JL, de Toledo MI, Barberato-Filho S. Decrease in penicillin Sales in Brazil after over-the-counter restrictions. Antimicrob Agents Chemother. 2015 Sep;59(9):5862-3. doi: 10.1128/AAC.01030-15.
2: Domínguez-Santos R, García-Estrada C, Kosalková K, Prieto C, Santamarta I, Martín JF. PcFKH1, a novel regulatory factor from the forkhead family, controls the biosynthesis of penicillin in Penicillium chrysogenum. Biochimie. 2015 Aug;115:162-76. doi: 10.1016/j.biochi.2015.05.015. Epub 2015 Jun 4. Epub 2016 Sep 28.
4: Chaturvedi V, Ertelt JM, Jiang TT, Kinder JM, Xin L, Owens KJ, Jones HN, Way SS. CXCR3 blockade protects against Listeria monocytogenes infection-induced fetal wastage. J Clin Invest. 2015 Apr;125(4):1713-25. doi: 10.1172/JCI78578. Epub 2015 Mar 9.