CAS: 32421-46-8; Bunaftide

该化合物是一种专门的有机化合物,其内含氯化萘核心,可与一个箱式氨化物组和第三层的矿物质侧链发生功能性作用.其结构设计具有独特的溶性和再活性特性,适合有机合成和制药中间体的应用.二乙基乙基乙基酸的存在增强了其作为协调化学的离子或催化剂的潜力.该化合物平衡的亲脂性和基本性促进了其在精细化学工艺中的实用性.其定义明确的分子结构确保了研究和工业环境中的一贯性能,特别是在需要定制的氨衍生物的情况下.

结构式图片

合成工艺路线路线简述

    海关参考信息

    专利信息


    专利号:US-10925977-B2
    优先权日:2006-10-05
    标 题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
    发明人:YANG DAVID J; YU DONGFANG; THOMPSON ANDREW S
    权利人:YANG DAVID J; YU DONGFANG; THOMPSON ANDREW S; CEIL POINT LLC; UNIV TEXAS
    摘要:Novel methods of synthesis of chelator-targeting ligand conjugates, compositions comprising such conjugates, and therapeutic and diagnostic applications of such conjugates are disclosed. The compositions include chelator-targeting ligand conjugates optionally chelated to one or more metal ions. Methods of synthesizing these compositions in high purity are also presented. Also disclosed are methods of imaging, treating and diagnosing disease in a subject using these novel compositions, such as methods of imaging a tumor within a subject and methods of diagnosing myocardial ischemia.

    专利号:US-10814013-B2
    优先权日:2006-10-05
    标 题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications

    专利号:AU-2007308022-A2
    优先权日:2006-10-05
    标题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications

    专利号:AU-2007308022-A1
    优先权日:2006-10-05
    标 题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications

    专利号:US-2008107598-A1
    优先权日:2006-10-05
    标 题:Efficient Synthesis of Chelators for Nuclear Imaging and Radiotherapy: Compositions and Applications

    专利号:AU-2007308022-B2
    优先权日:2006-10-05
    标题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献


    1: Kimura T, Nakazawa M, Imai S. [Electrophysiological effects of bunaftine, an antiarrhythmic drug, on action potential characteristics in ventricular muscle preparations]. Nihon Yakurigaku Zasshi. 1986 Jul;88(1):1-7. Japanese. doi: 10.1254/fpj.88.1. 21(11):2015-25. Italian. 236(1):107-15. doi: 10.1007/BF00216519. 9(5):535-9. Italian. 37(2):143-9. French. 22(11):1971-8. Italian. 22(1):99-116. Italian. 54(21):2075-7. Italian. 133(4):371-80. Italian. 133(4):363-70. Italian. 26(2):241-4. 26(1):29-36. Italian. 25(3):213-8. Italian. 25(3):223-8. French. 26(2):141-7. French. 24(1):79-84. Italian. 26(2):113-6. Italian. 25(4):355-8. Italian. 23(12):932-6. Italian. 67(40):2625-35. Italian.

    合成参考文献


    摘要:Merck Index; an Encyclopedia of Chemicals, Drugs, and Biologicals, 11th ed., Rahway, NJ 07065, Merck & Co., Inc. 1989, 11(226), 1989
    参考文献:10.1016/0014-2999(80)90483-5
    摘要:Tamargo J. Electrophysiological effects of bunaphtine on isolated rat atria. Eur J Pharmacol. 1980 Mar 07;62(1):81–8. doi: 10.1016/0014-2999(80)90483-5.
    📝 需求与反馈
    尽可能描述清楚需求与问题信息
    ×

    通知