CAS: 298709-29-2; 3,5-Difluoropicolinonitrile

相似化合物

745784-04-7 97509-75-6 915720-64-8

上下游产品

CAS号85331-33-5 3,5-二氯-2-氰基吡啶 | CAS号1075756-90-9 1-(3,5-二氟吡啶-2-基)乙酮 | CAS号1065267-10-8 3,5-二氟吡啶-2-甲酸乙酯 | CAS号745784-04-7 3,5-二氟-2-吡啶羧酸 | CAS号36057-45-1 2-氰基-3,5-二甲氧基吡啶 | CAS号780801-58-3 3,5-二氟吡啶-2-甲醛

3,5-二氯-2-氰基吡啶置于polyethylene Glycol 8000,Potassium Fluoride体系中,用 二甲基亚砜 用作溶剂,化学反应 0.5H,反应生成2-氰基-3,5-二氟吡啶
参考文献:Medicaments Against Viral Diseases
标题:Medicaments Against Viral Diseases
摘要:新型二氢嘧啶和其他抗病毒药物的组合,适用于对抗hbv感染.

专利信息

专利号:US-9957277-B2
优先权日:2015-11-25
标题 :eIF4A-inhibiting compounds and methods related thereto
发明人：ERNST JUSTIN T; REICH SIEGFRIED H; SPRENGELER PAUL A; TRAN CHINH VIET; PACKARD Garrick Kenneth; XIANG ALAN X; NILEWSKI CHRISTIAN; MICHELS THEO
权利人:EFFECTOR THERAPEUTICS INC
摘要:The present invention provides synthesis, pharmaceutically acceptable formulations and uses of compounds in accordance with Formula I, or a stereoisomer, tautomer or pharmaceutically acceptable salt thereof. n nFor Formula I compounds X, Y, R 1 , R 2 , R 3a , R 3b , R 4a , R 4b and R 5 are as defined in the specification. The inventive Formula I compounds are inhibitors of eIF4A and find utility in any number of therapeutic applications, including but not limited to treatment of inflammation and various cancers.