CAS: 26825-92-3; Methyl8-Bromooctanoate

相似化合物

17696-11-6 50816-19-8 54049-24-0

上下游产品

辛二酸单甲酯 Suberic Acid Monomethyl Ester 3946-32-5
8-羟基辛酸甲酯 8-Hydroxyoctanoic Acid Methyl Ester 20257-95-8
壬二酸氢甲酯 Azelaic Monomethyl Ester 2104-19-0
8-溴辛酸 8-Bromo-Octanoic Acid 17696-11-6
6-溴己酸 6-Bromocaproic Acid 4224-70-8
壬二酸 Azelaic Acid 123-99-9

8-溴辛酸置于甲醇,对甲苯磺酸体系中,用 苯 用作溶剂,化学反应 48.0H,以97%的收率获得8-溴辛酸甲酯
参考文献:I型对映体植物前列腺素b1的简短合成
标题:I型对映体植物前列腺素b1的简短合成
摘要:据报道,由3-[((二甲氧基磷酰基)甲基]环戊-2-烯酮合成了植物前列腺素b 1型的两种对映体.它包括三个步骤,包括在c(2)用8-溴辛酸甲酯对底物进行区域选择性烷基化,随后与对映体o-苯甲酰基保护的α-羟基丁醛进行horner反应和最终甲醇分解.这使产物的总产率为25%. 植物前列腺素-环戊烯酮膦酸酯-烷基化-霍纳链-全合成
Doi:10.1055/s-0029-1216883

专利信息

专利号:US-9751851-B2
优先权日:2013-09-20
标 题:Molecules and compositions that inhibit gram negative bacteria and their uses
发明人：BASSLER BONNIE L; SEMMELHACK MARTIN F; DRESCHER KNUT; SIRYAPORN ALBERT; CONRAD-MILLER LAURA C; O'LOUGHLIN COLLEEN T
权利人:UNIV PRINCETON; BASSLER BONNIE L; SEMMELHACK MARTIN F; DRESCHER KNUT; SIRYAPORN ALBERT; MILLER LAURA C; O'LOUGHLIN COLLEEN T
摘要:Antivirulence strategies to combat Pseudomonas aeruginosa , are described. One strategy encompasses synthesis of a series of compounds that inhibit the production of pyocyanin, a redox-active virulence factor produced by this pathogen. A related strategy encompasses synthesis of compounds that inhibit the two P. aeruginosa quorum-sensing receptors, LasR and RhlR, inhibit production of pyocyanin, and inhibit biofilm formation.

专利号:US-4539410-A
优先权日:1982-09-30
标题:N-Substituted-2-(1-imidazolyl)indoles
发明人：RENFROE HARRIS B
权利人:CIBA GEIGY CORP
摘要:Various 1-carboxylic acid substituted-2-(1-imidazolyl)indoles and functional derivatives thereof are highly specific thromboxane synthetase inhibitors. Synthesis of, pharmaceutical compositions thereof, methods of treatment utilizing such compounds and intermediates for their synthesis are included.

专利号:US-2018208555-A1
优先权日:2013-11-18
标题 :Method of synthesis of an ionizable cationic lipid

专利号:US-7320993-B1
优先权日:1997-12-17
标题 :Aryl-substituted pyridylalkane, alkene, and alkine carboxamides useful as cytostatic useful as cytostatic and immuosuppressive agents
发明人：BIEDERMANN ELFI; HASMANN MAX; LOESER ROLAND; RATTEL BENNO; REITER FRIEDEMANN; SCHEIN BARBARA; SEIBEL KLAUS; VOGT KLAUS; WOSIKOWSKI KATJA; SCHEMAINDA ISABEL
权利人:ASTELLAS DEUTSCHLAND GMBH
摘要:The invention relates to new pyridylalkane, alkene, and alkine acid amides substituted with an aryl and/or heteroaryl residue according to the general formula (I), with a saturated or one or several-fold unsaturated hydrocarbon residue in the carboxylic acid group, methods for the synthesis of these compounds, medicaments containing these and their production as well as their therapeutic use, especially as cytostatic agents and immunosuppressive agents, for example in the treatment or prevention of various types of tumors and control of immune reactions such as autoimmune diseases.

专利号:US-10781169-B2
优先权日:2013-11-18
标 题:Method of synthesis of an ionizable cationic lipid

专利号:US-2021002217-A1
优先权日:2013-11-18
标题:Method of synthesis of an ionizable cationic lipid