CAS: 2048-57-9; 2-Thienylisocyanate

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CAS号527-72-0 2-噻吩甲酸 | CAS号17698-15-6 2-Thiophenecarb... | CAS号5271-67-0 2-噻吩甲酰氯 | CAS号4648-54-8 叠氮基三甲基硅烷 | CAS号105995-16-2 2-噻吩基氨基甲酸乙酯

📜2-噻吩甲酸置于叠氮磷酸二苯酯,三乙胺体系中,用 甲苯 用作溶剂,化学反应 6.0H,反应生成2-噻吩异氰酸酯
参考文献: Compounds For Treating Viral Infections[fr] Composés Pour Traiter Des Infections Virales
标题: Compounds For Treating Viral Infections[fr] Composés Pour Traiter Des Infections Virales
摘要:本发明涉及小分子化合物及其在治疗疾病中的应用,特别是病毒性疾病,尤其是丙型肝炎病毒(hcv).

专利信息

专利号:US-2019211134-A1
优先权日:2016-08-19
标 题 :Thiourethane polymers, method of synthesis thereof and use in fused filament fabrication printing
发明人：ELLSON GREGORY T; LUND BENJAMIN R; VOIT WALTER
权利人:BOARD OF REGENTS THE UNIV OF TEXAS; ADAPTIVE 3D TECH
摘要:A thermoplastic thiourethane polymer comprising a sequential chain of a first type of monomer covalently bonded to a second type of monomer via thiourethane linkages. The first type of monomer includes two or more thiol functional groups and the type of monomer includes two or more isocyanate functional groups. The first and second types of monomers are polymerized together in an anhydrous aprotic solvent-dissolved anionic step-growth polymerization reaction that is catalyzed by a non-nucleophillic base having a pKa greater than 7.

专利号:US-10899072-B2
优先权日:2016-03-15
标题:Thiourethane polymers, method of synthesis thereof and use in additive manufacturing technologies
发明人：ELLSON GREGORY T; LUND BENJAMIN R; VOIT WALTER
权利人:UNIV TEXAS; ADAPTIVE 3D TECH; BOARD OF RESENTS THE UNIV OF TEXAS SYSTEM
摘要:A semi-crystalline thiourethane polymer. The semi-crystalline thiourethane polymer comprises a sequential chain of a first type of monomer covalently bonded to a second type of monomer via thiourethane linkages. Each of the first type of monomer includes two or more thiol functional groups and each of the second type of monomer includes two or more isocyanate functional groups. The first and second types of monomers are polymerized together in an anionic step-growth polymerization reaction that is catalyzed by a non-nucleophillic base having a pKa greater than 7, produced by photo-initiated decomposition of a photolatent base. A method of synthesizing, and polymer jetting and stereolithography methods of manufacturing a polymer part, are also disclosed.

专利号:US-2005192265-A1
优先权日:2003-03-20
标 题:Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting beta-amyloid peptide release and/or its synthesis by use of such compounds
发明人：THOMPSON RICHARD C; WILKIE STEPHEN; STACK DOUGLAS R; VANMETER ELDON E; SHI QING; BRITTON THOMAS C; AUDIA JAMES E; REEL JON K; MABRY THOMAS E; DRESSMAN BRUCE A; CWI CYNTHIA L; HENRY STEVEN S; MCDANIEL STACEY L; STUCKY RUSSELL D; PORTER WARREN J
摘要:Disclosed are compounds which inhibit β-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions that include a compound which inhibits β-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.

专利号:US-6906056-B2
优先权日:1998-06-22
标 题:Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds
发明人：THOMPSON RICHARD C; WILKIE STEPHEN; STACK DOUGLAS R; VANMETER ELDON E; SHI QING; BRITTON THOMAS C; AUDIA JAMES E; REEL JON K; MABRY THOMAS E; DRESSMAN BRUCE A; CWI CYNTHIA L; HENRY STEVEN S; MCDANIEL STACEY L; STUCKY RUSSELL D; PORTER WARREN J
权利人:LILLY CO ELI
摘要:Disclosed are compounds which inhibit β-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions that include a compound which inhibits β-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.

专利号:US-9833457-B2
优先权日:2008-01-25
标题:Tricyclic compounds as modulators of TNF-α synthesis and as PDE4 inhibitors
发明人：MJALLI ADNAN M M; GADDAM BAPU; POLISETTI DHARMA RAO; KOSTURA MATTHEW J; GUZEL MUSTAFA
权利人:VTV THERAPEUTICS LLC
摘要:The present invention relates to chemical compounds of Formula (I) are as herein defined, pharmaceutical compositions, and methods of use in the treatment of conditions or disorders mediated by TNF-α or by PDE4, including but not limited to psoriatic arthritis.

专利号:US-11155670-B2
优先权日:2016-08-24
标题:Amorphous thermoset thiourethane polymers, method of synthesis thereof and use in bio-electronic devices
发明人：ELLSON GREGORY T; VOIT WALTER
权利人:UNIV TEXAS
摘要:An amorphous thermoset thiourethane polymer, comprising a sequential chain of a first type of monomer covalently bonded to a second type of monomer via thiourethane linkages, wherein the first type of monomer includes two or more thiol functional groups and the second type of monomer includes two or more isocyanate functional groups. Methods of synthesizing the polymer, bio-electronic devices comprising the polymer and methods of manufacturing such devices are disclosed.