CAS: 178468-00-3; 8-((2S,3R,4R,5S,6R)-3,4-Dihydroxy-6-(Hydroxymethyl)-5-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-2-yl)Oxy)Tetrahydro-2H-Pyran-2-yl)-5,7-Dihydroxy-2-(4-Hydroxyphenyl)-4H-Chromen-4-One
该化合物是一种来自天然化合物VItexin的浮质胶层,其特点是附在4'位置上的葡萄糖.这一修改与其对口的甘油相比,提高了溶性和生物利用率.作为二级植物代谢物,它表现出显著的抗氧化剂和抗炎特性,使其在药理学和营养学研究中具有相关性.它的稳定性和结构特性允许在研究氧化性应激相关机制方面可能的应用.在HPLC和LC-MS中使用了Vitexin-4'-O-Glucoside的分析标准,用于定性和定量分析,确保在复杂的基质中准确识别.化合物具有生物活性潜力的学术和工业环境都对化合物感兴趣.
- 英文名称8-((2S,3R,4R,5S,6R)-3,4-Dihydroxy-6-(Hydroxymethyl)-5-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-2-yl)Oxy)Tetrahydro-2H-Pyran-2-yl)-5,7-Dihydroxy-2-(4-Hydroxyphenyl)-4H-Chromen-4-One
- 中文名称牡荆素-4''-O-葡萄糖苷
- IUPAC名称8-((2S,3R,4R,5S,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one
- 其它别名Vitexin 4 - -D-Glucopyranosyl; Vitexin-4''-O-Glucoside; (1S)-1,5-Anhydro-1-[5,7-Dihydroxy-2-(4-Hydroxyphenyl)-4-Oxo-4H-1-Benzopyran-8-Yl]-4-O-Beta-D-Glucopyranosyl-D-Glucitol; Vitexin Glucoside; Vitexin -4'
- CAS编号178468-00-3
- MFCD编号:MFCD18827497
- 分子式:C27H30O15分子量:594.52
- 产品CID: 916316
- 产品分类分析化学 → 标准品 → 药典标准品和杂质标准品
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主要参考文献
1: Hou K, Chen F, Zu Y, Yang L. Ionic liquids-lithium salts pretreatment followed by ultrasound-assisted extraction of vitexin-4″-O-glucoside, vitexin-2″-O-rhamnoside and vitexin from Phyllostachys edulis leaves. J Chromatogr A. 2016 Jan 29;1431:17-26. doi: 10.1016/j.chroma.2015.12.067. Epub 2015 Dec 30. doi: 10.1016/j.jchromb.2015.10.043. Epub 2015 Oct 30. doi: 10.1186/s13065-017-0317-x.
4: Wei W, Ying X, Zhang W, Chen Y, Leng A, Jiang C, Liu J. Effects of vitexin-2"-O-rhamnoside and vitexin-4"-O-glucoside on growth and oxidative stress-induced cell apoptosis of human adipose-derived stem cells. J Pharm Pharmacol. 2014 Jul;66(7):988-97. doi: 10.1111/jphp.12225. Epub 2014 Feb 17. doi: 10.1002/bmc.2931. Epub 2013 Jun 13.
合成参考文献
参考文献:10.1016/j.bmcl.2021.128211
摘要:Pang X, Wang M, Wang SY, Zhang J, Du YP, Zhao Y, Zheng XH, Ma BP. Phenolic compounds from the leaves of Crataegus pinnatifida Bge. var. major N.E.Br. And their lipid-lowering effects. Bioorg Med Chem Lett. 2021 Sep 01;47():128211. doi: 10.1016/j.bmcl.2021.128211.
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