CAS: 118-69-4; 2,6-Dichlorotoluene

上下游产品

CAS号872-50-4 N-甲基吡咯烷酮(NMP) | CAS号865-33-8 甲醇钾 | CAS号21452-18-6 甲硫砜 | CAS号30595-79-0 2,6-二氯苯乙醇 | CAS号2225-18-5 3,5-Dichloro-4-... | CAS号39652-34-1 3,5-二氯-4-甲基苯甲酸 | CAS号104-15-4 对甲苯磺酸 | CAS号99-94-5 对甲基苯甲酸 | CAS号59714-30-6 (2,6-dichloroph... | CAS号98-59-9 对甲苯磺酰氯(PTSC) | CAS号54454-12-5 3-氯-2-甲基苯甲腈 | CAS号3260-88-6 2-氯-6-甲氧基甲苯 | CAS号6575-24-2 2,6-二氯苯基乙酸 | CAS号39652-34-1 3,5-二氯-4-甲基苯甲酸 | CAS号83277-23-0 2,4-二氯-3-甲基苯甲酸 | CAS号443-84-5 2,6-二氟甲苯 | CAS号50-30-6 2,6-二氯苯甲酸 | CAS号50-31-7 2,3,6-三氯苯甲酸 | CAS号20973-90-4 2,6-二氯苯乙醛 | CAS号28269-31-0 2-甲基异邻苯二甲酸二甲酯

3,5-Dichloro-4-Methylbenzenesulphonic Acid置于copper(I) Oxide,硫酸体系中,用 喹啉 用作溶剂,化学反应 3.0H,以93%的收率获得2,6-二氯甲苯
参考文献:Oxidative Chlorination,Desulphonation,Or Decarboxylation To Synthesize Pharmaceutical Intermediates: 2,6-Dichlorotoluene,2,6-Dichloroaniline,And 2,6-Dichlorophenol
标题:Oxidative Chlorination,Desulphonation,Or Decarboxylation To Synthesize Pharmaceutical Intermediates: 2,6-Dichlorotoluene,2,6-Dichloroaniline,And 2,6-Dichlorophenol
摘要:
Doi:10.1021/op9800515

专利信息

专利号:US-11548898-B2
优先权日:2017-07-06
标题 :Synthesis of halichondrins
发明人：KISHI YOSHITO; AI YANRAN; YE NING; WANG QIAOYI; YAHATA KENZO; ISO Kentaro; NAINI SANTHOSH REDDY; YAMASHITA SHUJI; LEE JIHOON; OHASHI ISAO; FUKUYAMA TAKASHI
权利人:HARVARD COLLEGE; EISAI R&D MAN CO LTD
摘要:The present invention provides methods for the synthesis of ketones involving a Ni/Zr-mediated coupling reaction. The Ni/Zr-mediated ketolization reactions can be used in the synthesis of halichondrins (e.g., halichondrin A, B, C; homohalichondrin A, B, C; norhalichondrin A, B, C), and analogs thereof. Therefore, the present invention also provides synthetic methods useful for the synthesis of halichondrins, and analogs thereof. Also provided herein are compounds (i.e., intermediates) useful in the synthesis of halichondrins, and analogs thereof. In particular, the present invention provides methods and compounds useful in the synthesis of compound of Formula (H3-A).

专利号:US-2008287649-A1
优先权日:2006-12-29
标 题 :Methods for the synthesis of cyclic peptides
发明人：CHEN LIN; HAN YEUN-KWEI; ROBERTS CHRISTOPHER R
权利人:CHEN LIN; HAN YEUN-KWEI; ROBERTS CHRISTOPHER R
摘要:Methods for the synthesis of cyclic peptides are provided, as well as novel dipeptide compounds. The methods include the solid phase synthesis of a dipeptide, which is the coupled to a second peptide in a solid phase reaction. The peptide is then cyclized following the coupling reaction. The methods and dipeptides are particularly useful for the synthesis of MC-4 receptor agonist peptides.

专利号:WO-9312076-A1
优先权日:1991-12-13
标题:Reagents for automated synthesis of peptide analogs
发明人：WEBB THOMAS ROY
权利人:CORVAS INT INC
摘要:Reagents suitable for synthesis of peptide analogs using automated peptide synthesis and procedures for synthesis of peptide analogs are provided.

专利号:US-2004242897-A1
优先权日:2002-07-31
标题 :Universal support media for synthesis of oligomeric compounds
发明人：GUZAEV ANDREI P; MANOHARAN MUTHIAH
摘要:Compounds for the synthesis of oligomeric compounds, particularly oligonucleotides and oligonucleotide mimetics, are provided. In addition, methods for functionalizing a support medium with a first monomeric subunit and methods for the synthesis of oligomeric compounds utilizing the novel compounds bound to support media are provided.

专利号:US-5283293-A
优先权日:1990-12-14
标 题:Reagents for automated synthesis of peptide analogs
发明人：WEBB THOMAS R
权利人:CORVAS INC
摘要:Reagents suitable for synthesis of peptide analogs using automated peptide synthesis and procedures for synthesis of peptide analogs are provided.

专利号:US-6770436-B1
优先权日:1996-11-14
标题:Chemical amplification for the synthesis of patterned arrays
发明人：BEECHER JODY E; GOLDBERG MARTIN J; MCGALL GLENN H
权利人:AFFYMETRIX INC
摘要:Radiation-activated catalysts (RACs), autocatalytic reactions, and protective groups are employed to achieve a highly sensitive, high resolution, radiation directed combinatorial synthesis of pattern arrays of diverse polymers. When irradiated, RACs produce catalysts that can react with enhancers, such as those involved in autocatalytic reactions. The autocatalytic reactions produce at least one product that removes protecting groups from synthesis intermediates. This invention has a wide variety of applications and is particularly useful for the solid phase combinatorial synthesis of polymers.