CAS: 7149-65-7; Ethyl (S)-5-Oxopyrrolidine-2-Carboxylate

上下游产品

CAS号64-17-5 乙醇 | CAS号98-79-3 L-焦谷氨酸 | CAS号75-03-6 碘乙烷 | CAS号56-86-0 L-谷氨酸 | CAS号115445-33-5 (S)-1-allyl-5-o... | CAS号14842-41-2 (5aS,10aS)-1H,5... | CAS号16450-41-2 谷氨酸二乙酯 | CAS号1118-89-4 L-谷氨酸二乙酯盐酸盐 | CAS号106191-02-0 (S)-5-(((叔丁基二甲基... | CAS号361440-67-7 (1S,3S,5S)-3-(氨... | CAS号334769-80-1 (2S,5S)-N-B°C-5... | CAS号51693-17-5 (S)-(+)-5-羟甲基-2... | CAS号194594-24-6 5-甲氧基吡咯烷-1,2-二羧... | CAS号64-17-5 乙醇 | CAS号98-79-3 L-焦谷氨酸 | CAS号147-85-3 脯氨酸 | CAS号23356-96-9 L-脯氨醇 | CAS号72479-05-1 (S)-5-溴甲基-2-吡咯烷酮

L-焦谷氨酸置于草酰氯,糖精体系中,用 二氯甲烷 作为反应溶剂,化学反应 2.58H,反应生成 L-焦谷氨酸乙酯
参考文献:吡咯烷酮的研究.焦谷氨酰氯的改进合成
标题:吡咯烷酮的研究.焦谷氨酰氯的改进合成
摘要:摘要 焦谷氨酸三甲基甲硅烷基酯与草酰氯在室温下反应容易反应生成焦谷氨酰氯.这种通过其他方法难以获得的不稳定化合物适用于制备焦谷氨酸酯和酰胺.
DOI:10.1080/00397919408010572

专利信息

专利号:US-2006074259-A1
优先权日:2004-10-01
标 题:Process for the enzymatic synthesis of pyroglutamic esters
发明人：PASCALY MATTHIAS; THUM OLIVER
权利人:GOLDSCHMIDT GMBH
摘要:A process for the preparation of compounds according to the general formula (I), n nin which R is a hydrocarbon radical of an alcohol, wherein one or more alcohols of the general formula (II) n nR—OH  (II)n nin which R is as defined above, are esterified and/or transesterified without using significant amounts of solvents, preferably without solvents, preferably under reduced pressure at temperatures below 100° C. in the presence of enzymes from the class of hydrolases with a compound according to the general formula (III), n n nin which R 1 is either hydrogen or a linear or branched alkyl or alkenyl group having 1 to 3 carbon atoms is provided.

专利号:BR-PI0710538-A2
优先权日:2006-04-20
标 题:process for the synthesis of a substantially pure stereoisomer, compounds, pharmaceutical composition comprising a compound, process for the synthesis of a compound and use thereof.

专利号:US-4975441-A
优先权日:1988-03-23
标 题:Lactams, their synthesis and use in cosmetic compositions
发明人：GIBSON WALTER T
权利人:UNILEVER PATENT HOLDINGS
摘要:A composition suitable for topical application to mammalian skin or hair for inducing, maintaining or increasing hair growth comprises: (i) a chemical inhibitor of glycosidase activity chosen from lactams having the structure: where A<1> and A<6> are -H, -CH3, - @@0, -CH2OT or @@@0 A<1> and A<6> being the same or different, and at least one of which being the group: @ @@o in a lactam ring; and where Q is -OT min , -NHT min or a lactam linkage to A<1> or A<6>; the Q groups being the same or different, and at least one of which is involved in a lactam linkage; and where T is the same or different and is chosen from -H, -CpH2p+1 or a metal ion, T min is -H or -COCpH2p+1, and p is an integer of from 1 to 22; provided that: where any of the Q groups is -OT min or -NHT min , then that group or groups can be of either stereochemical configuration with respect to the plane of the ring; and (ii) a cosmetically acceptable vehicle for the chemical inhibitor. Certain novel lactams are also claimed.

专利号:US-8835466-B2
优先权日:2006-04-20
标 题 :Synthesis and uses of pyroglutamic acid derivatives
发明人：Ã?LVAREZ BUILLA GÓMEZ JULIO; NOVELLA ROBISCO JOSÉ LUIS; MATÃ?A MARTÃ?N MA PAZ; SERNA PEREDA SONIA
权利人:Ã?LVAREZ BUILLA GÓMEZ JULIO; NOVELLA ROBISCO JOSÉ LUIS; MATÃ?A MARTÃ?N MA PAZ; SERNA PEREDA SONIA; PRODIMED SA
摘要:Novel pyroglutamic acid derivatives (I), wherein R 1 is —OH, —ORa, wherein Ra is alkyl, cycloalkyl, alkenyl, cycloalkenyl, aryl, aralkyl or heterocyclyl; R 2 , R 3 and R 4 are independently H, a nitrogen protecting group which hydrolyzes under acidic conditions or phtalamide; X is a pharmaceutically acceptable anion; and Y is a N-containing group; either in the form of their isolated optically active stereoisomers or in the form of mixtures thereof, are useful compounds for enhancing an immuneresponse in a subject and/or for treating tumors, bacterial, fungal or viral infections, or autoimmune diseases.

专利号:CA-1083586-A
优先权日:1976-08-05
标 题:Stereospecific synthesis of pyrrolidines

专利号:EP-1554235-A4
优先权日:2002-10-25
标 题:PROCESS FOR SYNTHESIS OF L-Y-METHYLENE GLUTAMINE SUSCE AND ANALOGUE