CAS: 615-79-2; Ethyl 2,4-Dioxopentanoate

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CAS号95-92-1 草酸二乙酯 | CAS号67-64-1 丙酮 | CAS号122-51-0 原甲酸三乙酯 | CAS号292638-85-8 丙烯酸甲酯 | CAS号107-91-5 氰乙酰胺 | CAS号141-52-6 乙醇钠 | CAS号71-43-2 苯 | CAS号56891-69-1 3-氰基-2-巯基-6-甲基吡... | CAS号34959-81-4 3-氯-2,4-二氧代戊酸乙酯 | CAS号5744-51-4 1,5-二甲基-1H-吡唑-3-甲酸乙酯 | CAS号5744-40-1 1,3-二甲基-1H-吡唑-5-甲酸乙酯 | CAS号3209-72-1 5-甲基-3-异噁唑羧酸乙酯 | CAS号63366-79-0 3-甲基-5-异噁唑羧酸甲酯 | CAS号35166-33-7 5-甲基-异噁唑-3-甲醇 | CAS号5744-59-2 1,5-二甲基-1H-吡唑-3-甲酸 | CAS号5744-56-9 1,3-二甲基-1H-吡唑-5-甲酸 | CAS号3405-77-4 5-甲基异噁唑-3-甲酸

草酸二乙酯置于ammonium Chloride体系中,用 乙醇,丙酮 作为反应溶剂,化学反应生成 乙酰丙酮酸乙酯
参考文献:Synthesis Of Camptothecin And Analogs Thereof
标题:Synthesis Of Camptothecin And Analogs Thereof
摘要:使用一种新型含羟基的三环中间体合成紫杉醇和紫杉醇类似物的方法,以及由该过程产生的紫杉醇类似物.这些紫杉醇类似物是有效的拓扑异构酶i抑制剂,并显示出抗白血病和抗肿瘤活性.

专利信息

专利号:US-6096898-A
优先权日:1999-10-22
标 题:One pot synthesis of 1,2,4-triazoles
发明人：PODHOREZ DAVID E; HULL JR JOHN W; BRADY CHRISTINE H
权利人:DOW AGROSCIENCES LLC
摘要:One pot synthesis of 1,2,4-triazoles uses thioimidate intermediate and 1,2-dichloroethane solvent.

专利号:WO-2025128848-A1
优先权日:2023-12-12
标题:Heterocyclic compounds as triggering receptor expressed on myeloid cells 2 agonists and methods of use
发明人：HOUZE JONATHAN B; PANDYA BHAUMIK
权利人:VIGIL NEUROSCIENCE INC
摘要:The present disclosure provides compounds of Formula (I), useful for the activation of Triggering Receptor Expressed on Myeloid Cells 2 ('TREM2'). This disclosure also provides pharmaceutical compositions comprising the compounds, uses of the compounds, and compositions for treatment of, for example, a neurodegenerative disorder. Further, the disclosure provides intermediates useful in the synthesis of compounds of Formula (I).

专利号:WO-2025128873-A1
优先权日:2023-12-12
标题:Heterocyclic pyridinone compounds as triggering receptor expressed on myeloid cells 2 agonists and methods of use
发明人：HOUZE JONATHAN B; PANDYA BHAUMIK
权利人:VIGIL NEUROSCIENCE INC
摘要:The present disclosure provides compounds of Formula (I), useful for the activation of Triggering Receptor Expressed on Myeloid Cells 2 ('TREM2'). This disclosure also provides pharmaceutical compositions comprising the compounds, uses of the compounds, and compositions for treatment of, for example, a neurodegenerative disorder. Further, the disclosure provides intermediates useful in the synthesis of compounds of Formula (I).

专利号:US-4894456-A
优先权日:1987-03-31
标题 :Synthesis of camptothecin and analogs thereof
发明人：WALL MONROE E; WANI MANSUKH C; NICHOLAS ALLAN W; MANIKUMAR GOVINDARAJAN
权利人:RES TRIANGLE INST
摘要:A method for synthesizing camptothecin and camptothecin analogs using a novel hydroxyl-containing tricyclic intermediate and the camptothecin analogs produced by the process. The camptothecin analogs are effective inhibitors of topoisomerase I and show anti-leukemic and anti-tumor activity.

专利号:US-4981968-A
优先权日:1987-03-31
标题:Synthesis of camptothecin and analogs thereof
发明人：WALL MONROE E; WANI MANSUKH C; NICHOLAS ALLAN W; MANIKUMAR GOVINDARAJAN
权利人:RES TRIANGLE INST
摘要:A method for synthesizing camptothecin and camptothecin analogs using a novel hydroxyl-containing tricyclic intermediate and the camptothecin analogs produced by the process. The camptothecin analogs are effective inhibitors of topoisomerase I and show anti-leukemic and anti-tumor activity.

专利号:EP-0436653-A4
优先权日:1988-09-28
标题 :Synthesis of camptothecin and analogs thereof