CAS: 36192-63-9; (2-Aminophenyl)(P-Tolyl)Methanone

上下游产品

2-N-(p-methylbenzenesulfonyl)amino-4'-methyl-benzophenone 2-(toluene-4-sulfonylamino)-benzoic acid (4-methylphenyl)(2-nitrophenyl)methanone p-toluoyl-benzoic acid amide2-p-toluoyl-benzoic acid amide N-(2-p-toluoyl-phenyl)-phthalimideN-(2-p-toluoyl-phenyl)-phthalimide (2-aminophenyl)(p-tolyl)methanol 2-amino-4'-methyldiphenylmethane p-tolyl-is°Chromeno[3,4-b]quinolin-5-one12-p-tolyl-is°Chromeno[3,4-b]quinolin-5-one

📜2-(Toluene-4-Sulfonylamino)-Benzoyl Chloride置于三氯化铝,硫酸体系中,化学反应 4.25H,反应生成2-氨基-4'-甲基苯甲酮
参考文献:Synthesis And Biological Evaluation Of Substituted 2-Sulfonyl-Phenyl-3-Phenyl-Indoles: A New Series Of Selective Cox-2 Inhibitors
标题:Synthesis And Biological Evaluation Of Substituted 2-Sulfonyl-Phenyl-3-Phenyl-Indoles: A New Series Of Selective Cox-2 Inhibitors
摘要:A New Series Of Substituted 2-Sulfonyphenyl-3-Phenyl-Indole Derivatives Were Synthesized And Evaluated For Their Ability To Inhibit Cox-2 And Cox-Lenzymes. Most Of The Compounds Synthesized Were Found To Be Highly Potent And Selective Inhibitors Of Cox-2. This Work Led To The Discovery Of 2-Aminosulfonylphenyl-3-Phenyl-Indole 5A Which Possesses Higher Activity And Selectivity For Cox-2 Than Celecoxib Both In Vitro And In Vivo. (C) 2003 Elsevier Science Ltd. All Rights Reserved.
Doi:10.1016/s0968-0896(03)00046-4