CAS: 288-39-1; 1,2,5-Thiadiazole

上下游产品

P-phenyl-P,P'-propane-1,3-diyldiamino-bis-phosphonium; dichloridehexa-P-phenyl-P,P'-propane-1,3-diyldiamino-bis-phosphonium; dichloride ethylenediamine 1,2-diaminoethane dihydr°Chloride Thiophene-2-thiol bis(thien-2-yl)sulfide 3-(2-thienyl)-1,2,5-selenadiazole diethyl sulphide

📜乙二胺置于tetrasulphur Tetranitride体系中,用 Xylene 用作溶剂,化学反应 3.0H,反应生成1,2,5-噻二唑
参考文献:Bertini,V.; De Munno,A.,Gazzetta Chimica Italiana,1971,Vol. 101,P. 259-268
标题:Bertini,V.; De Munno,A.,Gazzetta Chimica Italiana,1971,Vol. 101,P. 259-268

专利信息

专利号:US-12291596-B2
优先权日:2018-11-30
标 题 :Radical cascade-enabled synthesis of precision polymers with complex main-chain structures
发明人：NIU JIA; HUANG HANCHU; WANG WENQI
权利人:THE TRUSTEES OF BOSTON COLLEGE
摘要:Radical cascade reactions enabling sequence-controlled ring-closing polymerization and ring-opening polymerization for the controlled synthesis of polymers with complex main-chain structures are provided. Facile syntheses leading to low-strain macrocyclic monomers consisting of the ring-opening triggers and extended main-chain structures are also provided. The present disclosure further provides methods for excellent control over polymer molecular weights and molecular weight distributions and high chain-end fidelity allows for the preparation of polymeric systems with well-defined architectures. Further provided are the general nature of the radical cascade-triggered transformations in polymer chemistry, and its application to the synthesis of polymers with diverse main-chain structural motifs with tailored functions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.

专利号:US-11161827-B2
优先权日:2019-04-05
标 题 :Catalytic systems for stereoselective synthesis of chiral amines by enantiodivergent radical C—H amination
发明人：Zhang xiao-xiang; Lang kai
权利人:TRUSTEES BOSTON COLLEGE; THE TRUSTEES OF BOSTON COLLEGE
摘要:In one aspect, the disclosure relates to a mode of asymmetric induction in radical processes based on sequential combination of enantiodifferentiative H-atom abstraction and stereoretentive radical substitution. Also disclosed is an asymmetric system for stereoselective synthesis of strained 5-membered cyclic sulfamides via radical 1,5-C—H amination of sulfamoyl azides. The disclosed metalloradical system can control the degree and sense of asymmetric induction in the catalytic radical C—H amination in a systematic manner. The disclosed system is applicable to a broad scope of substrates with different types of C(sp 3 )—H bonds and exhibits reactivity and selectivity, providing access to both enantiomers of useful 5-membered cyclic sulfamides in a highly enantioenriched form. Also disclosed are catalysts useful in these processes. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.

专利号:US-10711138-B2
优先权日:2016-04-08
标题:Intermediates and procedures for the synthesis of functional materials
发明人：KIRSCH PEER; GUNST SUSANN
权利人:MERCK PATENT GMBH
摘要:The present invention relates to heteroaromatic compounds which have two different reactive groups, their use in the synthesis of asymmetrically substituted compounds, and synthesis processes in which the compounds according to the invention are reacted sequentially with two different compounds, whereby an asymmetrically substituted compound is formed.

专利号:US-11186678-B2
优先权日:2018-11-30
标 题 :Radical cascade-enabled synthesis of precision polymers with complex main-chain structures
发明人：NIU JIA; HUANG HANCHU; WANG WENQI
权利人:TRUSTEES BOSTON COLLEGE
摘要:Radical cascade reactions enabling sequence-controlled ring-closing polymerization and ring-opening polymerization for the controlled synthesis of polymers with complex main-chain structures are provided. Facile syntheses leading to low-strain macrocyclic monomers consisting of the ring-opening triggers and extended main-chain structures are also provided. The present disclosure further provides methods for excellent control over polymer molecular weights and molecular weight distributions and high chain-end fidelity allows for the preparation of polymeric systems with well-defined architectures. Further provided are the general nature of the radical cascade-triggered transformations in polymer chemistry, and its application to the synthesis of polymers with diverse main-chain structural motifs with tailored functions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.

专利号:US-11912647-B2
优先权日:2020-05-22
标 题:Diversity-oriented synthesis of N,N,O-trisubstituted hydroxylamines from alcohols and amines by N—O bond formation
发明人：CRICH DAVID; HETTIKANKANAMALAGE ASIRI; HILL JARVIS
权利人:UNIV GEORGIA
摘要:In one aspect, the disclosure relates to a method for the direct synthesis of complex N,N,O-trisubstituted hydroxylamines by N—O bond formation. In another aspect, the method can successfully be employed using a wide variety of commercially available alcohols and secondary amines and enables the construction of large fragment-based libraries of trisubstituted hydroxylamines for drug discovery purposes. Also disclosed are N,N,O-trisubstituted hydroxylamines having low basicity, high stability at ambient temperatures, and an inherent lack of reactivity towards acetylating and sulfonylating enzymes that confer mutagenicity on less-substituted hydroxylamines.

专利号:US-10981922-B2
优先权日:2012-04-26
标题 :Synthesis of lactams
发明人：TAVARES FRANCIS XAVIER
权利人:TAVARES FRANCIS XAVIER
摘要:Methods for the synthesis of lactams are presented whereby a carboxylic acid of the formula HOOC—OR—NH-LG, wherein OR is an organic moiety and LG is a leaving group, is reacted with an acid, such as an organic acid, in particular a strong acid, and a dehydrating agent, which may be one in the same such as a strong acid anhydride, such that the amount of acid added allows for the desired transformation to take place without the loss of the leaving group (LG) before the cyclization, and recovering the lactam.