专利号:US-2016317682-A1 优先权日:2015-04-30 标题:PREPARATION OF Ag18F AND ITS USE IN THE SYNTHESIS OF PET RADIOTRACERS 发明人:SCOTT PETER J H; BROOKS ALLEN F; ICHIISHI NAOKO; SANFORD MELANIE S 权利人:UNIV MICHIGAN REGENTS; THE REGENTS OFTHE UNIV OF MICHIGAN 摘要:Copper-catalyzed radiofluorination of aryl iodides using Ag 18 F, methods of preparing Ag 18 F, and compounds obtained by copper-catalyzed radiofluorination of aryl iodides using Ag 18 F are disclosed. Diagnostic and therapeutic methods involving such compounds also are disclosed.
专利号:US-2024360125-A9 优先权日:2021-02-22 标 题 :2-substituted bicyclo[1.1.1]pentanes 发明人:MACMILLAN DAVID W; GARRY OLIVIA L; LIANG YUFAN; HEILMANN MICHAEL 权利人:UNIV PRINCETON 摘要:Provided herein are 2-substituted bicyclo[1.1.1]pentane (BCP) compounds, as well as methods of making the 2-substituted BCP compounds and methods of derivatizing the 2-substituted BCP compounds, particularly at the 2-position. The 2-substituted BCP compounds described herein are useful building blocks in the synthesis of a variety of products, including pharmaceuticals, polymers, liquid crystals, monolayers and supramolecular structures.
专利号:CN-120041848-A 优先权日:2025-02-18 标 题 :Method for electrochemically synthesizing chiral beta-ester nitrile and application of chiral beta-ester nitrile in synthesis of baclofen and rolipram
专利号:CN-117623998-A 优先权日:2023-12-05 标 题:Application of perfluorocarbon sulfur-based silver reagent in synthesis of aryl perfluoroethyl sulfide
专利号:US-5346995-A 优先权日:1991-11-25 标题:Preparation of copper 2-alkoxyisobutylisonitrile complexes and 99m Tc labelling of 2-alkoxyisobutylisonitrile 发明人:TE-WEI LEE; GANN TING; CHANG-SHINN SU; SHYH-YI CHYI 权利人:INST NUCLEAR ENERGY RES 摘要:A new method for synthesizing 2-alkoxyisobutylisonitrile is provided in which isobutylene is used as the starting material. The haloalkoxylation of isobutylene in alcohol medium gives 2-alkoxyisobutylhalide which is then converted to 2-alkoxyisobutylamine. In the basic condition, the reaction of 2-alkoxyisobutylamine with chloroform produces 2-alkoxyisobutylisonitrile. The synthesis process contains three steps by which a higher yield is achieved. 2-Alkoxyisobutylisonitrile is labelled with technetium-99m by exchange labelling of stable tetrakis(2-alkoxyisobutylisonitrile)copper(I) complex. Tetrakis(2-alkoxyisobutylisonitrile)copper(I) complex can be prepared by the exchange of acetonitrile molecules in tetrakis(acetonitrile)copper(I) complex with isonitrile ligands.
专利号:CN-114369248-B 优先权日:2020-10-15 标题 :A kind of chiral silicon-containing polyester and its synthesis method