CAS: 14257-40-0; (2R,3R,4S,5S,6R)-2-(Acetoxymethyl)-6-Chlorotetrahydro-2H-Pyran-3,4,5-Triyl Triacetate
该化合物是一个受保护的甘油基捐赠者,广泛用于碳水化合物化学,用于对含有含单氧的寡醇酸盐和甘醇的化合物进行立体选择性合成.乙基化合物提供了稳定性,便于受控的同化反应,而氯离子体组则增强了甘油基联结形成中的回动性.该化合物对于其高度的α选择性具有特别价值,使它成为建造α-联结曼诺侧的首选试剂.其晶体性质确保了始终的纯度,并且作为为生物医学和生物化学研究准备复杂的遗传结构的关键中间体.它适合于自动化合成,在溶相和固相方法上都具有可靠的性能.
- 英文名称(2R,3R,4S,5S,6R)-2-(Acetoxymethyl)-6-Chlorotetrahydro-2H-Pyran-3,4,5-Triyl Triacetate
- 中文名称α-D-甘露糖基氯化物 2,3,4,6-四乙酸酯
- IUPAC名称(2R,3R,4S,5S,6R)-2-(acetoxymethyl)-6-chlorotetrahydro-2H-pyran-3,4,5-triyl triacetate
- 其它别名2,3,4,6-Tetra-O-Acetyl-A-D-Mannopyranosylchloride; Chloro 2,3,4,6-Tetra-O-Acetyl-α-D-Mannopyranoside; 2,3,4,6-Tetra-O-Acetyl-α-D-Mannopyranosyl Chloride; 2,3,4,6-Tetra-O-Acetyl-A-D-Mannopyranosyl Chloride ,; Acetochloro-Alpha-D-Mannose, (2R,3R,4S,5S,6R)-2-(Acetoxymethyl)-6-Chlorotetrahydro-2H-Pyran-3,4,5-Triyl Triacetate; 6-Chloro-6-Deoxy-D-Mannose; Acetochloro-Alpha-D-Mannose; Alpha-Acetochloro-D-Mannose
- CAS编号14257-40-0
- MFCD编号:MFCD00067355
- 分子式:C14H19ClO9分子量:366.75
- 产品CID: 650998
- 产品分类生物化工 → 糖类化合物 → 单糖
物理性质
MSDS等安全信息
上下游产品
β-D-mannopyranose pentaacetate per-O-acetyl-α-D-mannopyranose 2,3,4,6-tetra-O-acetyl-D-mannopyranose 2-(Trimethylsilyl)ethyl-2,3,4,6-tetra-O-acetyl-α-D-mannopyranosid S)-1-(4-methoxy-phenyl)-1,5-anhydro-D-mannitol(1S)-1-(4-methoxy-phenyl)-1,5-anhydro-D-mannitol 2,3,4,6-tetra-O-acetyl-D-mannopyranose methyl 2-O-(2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyl)-3,4,6-tri-O-benzyl-α-D-glucopyranoside trimethylsilyl 2,3,4,6-tetra-O-acetyl-α-D-mannopyranoside合成工艺路线路线简述
海关参考信息
- 2905122000-异丙醇
2905310000-1,2-乙二醇
2905320000-1,2-丙二醇
2905399001-1,3-丙二醇 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-4252970-A
优先权日:1977-09-06
标题:6-Deoxyneamines
发明人：MAGERLEIN BARNEY J
权利人:UPJOHN CO
摘要:6-Deoxyneamine, 6-deoxy-5-epineamine, their 5-0-glycosyl derivatives, 6-deoxy-5-oxoneamine and the derivatives therefrom are useful as antibacterial agents and/or as intermediates in the synthesis of antibacterially active 6-deoxyneamines.
专利号:US-4131732-A
优先权日:1977-04-21
标题 :Method for preparing auranofin
发明人：HILL DAVID T; SUTTON BLAINE M; LANTOS IVAN
权利人:SMITHKLINE CORP
摘要:A new synthesis of auranofin comprising reacting 2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl bromide with triethylphosphinegold(I) chloride and sodium or potassiumsulfide. Auranofin is an antiarthritic pharmaceutical compound. Auranofin is an orally active therapeutic agent which is useful in man as an antiarthritic.
