CAS: 140472-69-1; 3-Bromo-5-Hydroxybenzoic Acid

相似化合物

199177-26-9 770718-92-8 1020336-51-9

上下游产品

CAS号188815-32-9 3-溴-5-碘苯甲酸 | CAS号42237-85-4 3-氨基-5-溴苯甲酸 | CAS号6307-83-1 3-硝基-5-溴苯甲酸 | CAS号121-92-6 间硝基苯甲酸 | CAS号56709-70-7 3-溴-5-甲氧基苯甲酸甲酯 | CAS号1020336-51-9 3-Bromo-5-(hydr... | CAS号157893-14-6 3-溴-5-甲氧基苯甲酸 | CAS号192810-12-1 3-溴-5-羟基苯甲酸甲酯 | CAS号1214324-49-8 3'-FLUORO-5-MET... | CAS号199177-26-9 3-溴-5-羟基苯甲醛 | CAS号855198-27-5 3-溴-5-乙氧基苯甲酸 | CAS号870673-35-1 ETHYL 5-BROMO-3...

3-氨基-5-溴苯甲酸置于硫酸,水,Sodium Nitrite体系中,化学反应 1.75H,以66%的收率获得3-溴-5-羟基苯甲酸
参考文献:(3-Oxo)Pyridazin-4-Ylurea Derivatives As Pde4 Inhibitors
标题:(3-Oxo)Pyridazin-4-Ylurea Derivatives As Pde4 Inhibitors
摘要:揭示了具有化学结构式(i)的新(3-氧代)吡啶并嘧啶-4-基脲衍生物;以及它们的制备方法,包含它们的药物组合物以及它们作为磷酸二酯酶iv(pde4)抑制剂在治疗中的用途.

专利信息

专利号:US-9388147-B2
优先权日:2009-11-13
标题 :Selective sphingosine 1 phosphate receptor modulators and methods of chiral synthesis
发明人：MARTINBOROUGH ESTHER; BOEHM MARCUS F; YEAGER ADAM RICHARD; TAMIYA JUNKO; HUANG LIMING; BRAHMACHARY ENUGURTHI; MOORJANI MANISHA; TIMONY GREGG ALAN; BROOKS JENNIFER L; PEACH ROBERT; SCOTT FIONA LORRAINE; HANSON MICHAEL ALLEN
权利人:RECEPTOS INC; CELGENE INTERNAT II SÃ RL
摘要:Compounds that selectively modulate the sphingosine 1 phosphate receptor are provided including compounds which modulate subtype 1 of the S1P receptor. Methods of chiral synthesis of such compounds are provided. Uses, methods of treatment or prevention and methods of preparing inventive compositions including inventive compounds are provided in connection with the treatment or prevention of diseases, malconditions, and disorders for which modulation of the sphingosine 1 phosphate receptor is medically indicated.

专利号:BR-122018077504-B1
优先权日:2009-11-13
标题 :METHODS FOR SYNTHESIS OF SELECTIVE SPHINGOSINE 1 PHOSPHATE RECEPTOR MODULATORS

专利号:EP-3406142-B1
优先权日:2009-11-13
标题:Selective sphingosine 1 phosphate receptor modulators and methods of chiral synthesis

专利号:WO-2024159285-A1
优先权日:2023-01-30
标题 :Nav1.7- and/or nav1.8-inhibiting aryl pyridine compounds, processes for the preparation thereof, compositions, uses, methods for treatment using same, and kits
发明人：BARREIRO GABRIELA; SANT’ANA DANILO PEREIRA DE; MONTEIRO JÚLIA LAMMOGLIA; GAMBA LUIS EDUARDO REINA; LIMA Là DIA MOREIRA; FRAGA CARLOS ALBERTO MANSSOUR; BARREIRO ELIEZER JESUS DE LACERDA
权利人:EUROFARMA LABORATORIOS S A; UNIV FEDERAL DO RIO DE JANEIRO – UFRJ
摘要:The present invention relates to Nav1.7- and/or Nav1.8-inhibiting aryl pyridine compounds. More specifically, the present invention relates to aryl pyridines comprising formula (I): (I), in which the substituents R1 to R10 are selected independently of the groups defined in the description, as well as to processes for preparing same, compositions comprising at least one of these compounds, uses, treatment methods for treating or preventing pain-related pathologies, and kits. The present invention pertains to the fields of medicinal chemistry and organic synthesis, as well as to the treatment of pain-related diseases.

专利号:US-2014378541-A1
优先权日:2011-06-16
标题 :Synthetic Epigallocatechin Gallate (EGCG) Analogs
发明人：CHAN TAK-HANG; PAMU SREEDHAR; DOU QING PING; CHEN DI
权利人:CHAN TAK-HANG; PAMU SREEDHAR; DOU QING PING; CHEN DI; UNIV WAYNE STATE; UNIV MCGILL; UNIV HONG KONG POLYTECHNIC
摘要:Synthetic polyphenolic compounds of formula (I), their modes of synthesis, and pharmaceutical compositions thereof are provided herein. Use of the compounds and compositions described herein for treating cancer and for treating metabolic disorders is also provided.

专利号:US-2013231326-A1
优先权日:2009-11-13
标 题 :Selective sphingosine 1 phosphate receptor modulators and methods of chiral synthesis