CAS: 95311-97-0; 4-Tetradecylmorpholine
该化合物是主要来自Ganoderma lebraryum蘑菇(通常称为Reishi)的三叶类化合物,其特点是复杂的分子结构,包括多环和功能组,有助于其生物活性;甘地酸C具有各种药理特性,包括抗炎,抗氧化剂和潜在的抗癌影响,使其对传统医学和现代药理都感兴趣;其溶解性一般在水中较低,但可溶解于有机溶剂,许多三叶类典型的有机溶剂.该化合物的操作机制据信涉及调制各种信号路径,加强免疫反应,并展示对某些癌症细胞线的细胞毒性影响;此外,甘地酸C在促进心血管健康和改善肝功能方面的潜力也得到了研究.
- 英文名称4-Tetradecylmorpholine
- 中文名称灵芝酸 C1
- IUPAC名称4-tetradecylmorpholine
- 其它别名Ganoderic Acid C1; (25R)-7β-Hydroxy-3,11,15,23-Tetraoxo-5α-Lanost-8-En-26-Oic Acid; (25R)-7β-Hydroxy-3,11,15,23-Tetraoxolanost-8-En-26-Oic Acid; Ganoderic Acid C1(P)(Please Call); (7Beta,25R)-7-Hydroxy-3,11,15,23-Tetraoxo-Lanost-8-En-26-Oic Acid; (2R,6R)-6-[(5R,7S,10S,13R,14R,17R)-7-Hydroxy-4,4,10,13,14-Pentamethyl-3,11,15-Trioxo-1,2,5,6,7,12,16,17-Octahydrocyclopenta[a]Phenanthren-17-Yl]-2-Methyl-4-Oxoheptanoic Acid; Lanost-8-En-26-Oicacid, 7-Hydroxy-3,11,15,23-Tetraoxo-, (7B,25R)-; Lanost-8-En-26-Oic Acid, 7-Hydroxy-3,11,15,23-Tetraoxo-, (7β,25R)-
- CAS编号95311-97-0
- MFCD编号:MFCD04039841
- 分子式:C18H37NO分子量:283.5
- 产品CID: 2006252
- 产品分类生物化工 → 中草药成分
物理性质
MSDS等安全信息
合成工艺路线路线简述
海关参考信息
- 2901210000-乙烯
2901220000-丙烯
2905122000-异丙醇
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专利信息
专利号:CN-115960735-A
优先权日:2022-11-12
标 题:Saccharomyces cerevisiae engineering strain and application thereof in synthesis of benzylthioglycoside
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
1: Liu C, Yang N, Song Y, Wang L, Zi J, Zhang S, Dunkin D, Busse P, Weir D, Tversky J, Miller RL, Goldfarb J, Zhan J, Li XM. Ganoderic acid C1 isolated from the anti-asthma formula, ASHMI™ suppresses TNF-α production by mouse macrophages and peripheral blood mononuclear cells from asthma patients. Int Immunopharmacol. 2015 Aug;27(2):224-31. doi: 10.1016/j.intimp.2015.05.018. Epub 2015 May 21.
2: Liu C, Dunkin D, Lai J, Song Y, Ceballos C, Benkov K, Li XM. Anti- inflammatory Effects of Ganoderma lucidum Triterpenoid in Human Crohn's Disease Associated with Downregulation of NF-κB Signaling. Inflamm Bowel Dis. 2015 Aug;21(8):1918-25. doi: 10.1097/MIB.0000000000000439.
3: Srivastava KD, Dunkin D, Liu C, Yang N, Miller RL, Sampson HA, Li XM. Effect of Antiasthma Simplified Herbal Medicine Intervention on neutrophil predominant airway inflammation in a ragweed sensitized murine asthma model. Ann Allergy Asthma Immunol. 2014 Apr;112(4):339-47.e1-2. doi: 10.1016/j.anai.2014.01.021.
合成参考文献
参考文献:10.1615/intjmedmushrooms.v1.i2.40
摘要:Chen R, Yu D. Studies on the Triterpenoid Constituents of the Spores of Ganoderma lucidum (Curt.: Fr.) P. Karst. (Aphyllophoromycetideae). Int J Med Mushrooms. 1999;1(2):147–52. doi: 10.1615/intjmedmushrooms.v1.i2.40.
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