CAS: 93000-03-4; Boc-Dl-Met-Oh

该化合物是氨基氨酸甲基硫磷的衍生物,其特点是氨基氨基组中存在一种叔丁基羟基碳基(Boc)保护组,该化合物通常用于丙二烯合成中,并用作有机化学的中间体,因为它能够保护氨基功能,同时允许进一步的化学改造.Boc组在基本条件下保持稳定,但在酸性条件下可以去除,使它成为合成化学中的一种宝贵工具.Boc-DL-Met-OH是白到白外固体的一种,在极地有机溶剂中可溶解.其结构包括硫基原子,这是甲基的标志,有助于其生物化学特性.作为种族混合物,含有可影响其生物活动D-和L-Met-OH,

结构式图片

相似化合物

112883-40-6 1152-62-1 2488-15-5

物理性质

MSDS等安全信息

上下游产品

CAS号24424-99-5 二碳酸二叔丁酯 | CAS号59-51-8 DL-蛋氨酸 | CAS号348-67-4 D-蛋氨酸 | CAS号89037-64-9 Carbonic acid, ... | CAS号75-44-5 光气 | CAS号6297-53-6 DL-蛋氨酸乙酯盐酸盐 | CAS号13303-10-1 (4-硝基苯基)碳酸叔丁酯 | CAS号36207-43-9 2-氨基-N-羟基-4-甲硫基丁酰胺 | CAS号119927-71-8 tert-butyl N-(4...

合成工艺路线路线简述

  • 59-51-8 + 24424-99-5 = 93000-03-4
    反应条件:1.1 Reagents: Sodium Hydroxide Solvents: 1,4-Dioxane,Water; Rt -> 6 °C; 15 Min,6 °C; 3.5 H,Rt
    标题:Tetrahydrofuran Cα-Tetrasubstituted Amino Acids: Two Consecutive β-Turns In A Crystalline Linear Tripeptide
    作者:Maity,Prantik; Zabel,Manfred; Koenig,Burkhard
    参考文献:Journal Of Organic Chemistry 日期:2007 卷标:72(21) 页码:8046-8053]

    59-51-8 + 24424-99-5 = 93000-03-4
    反应条件:1.1 Reagents: Sodium Carbonate Solvents: 1,4-Dioxane,Water; 1 H,0 °C; Overnight,Rt1.2 Reagents: Citric Acid Solvents: Water; Ph 2 - 3,Cooled
    标题:The Development Of A New Class Of Inhibitors For Betaine-Homocysteine S-Methyltransferase
    作者:Picha,Jan; Vanek,Vaclav; Budesinsky,Milos; Mladkova,Jana; Garrow,Timothy A.; Et Al
    参考文献:European Journal Of Medicinal Chemistry 日期:2013 卷标:65 页码:256-275]

    59-51-8 + 24424-99-5 = 93000-03-4
    反应条件:1.1 Reagents: Sodium Hydroxide Solvents: 1,4-Dioxane,Water; 5 H,Rt
    标题:The Effect Of Mobile Phase And Dissolving Solvent On The Enantiomer Separation Using A Covalently Immobilized Chiral Column Derived From Polysaccharide Derivative
    作者:Huang,Hu; Lee,Beom-Gyu; Baek,Chae-Sun; Lee,Wonjae
    参考文献:Journal Of The Korean Chemical Society 日期:2009 卷标:53(2) 页码:137-143]

    59-51-8 + 24424-99-5 = 93000-03-4
    反应条件:1.1 Reagents: Triethylamine Solvents: 1,4-Dioxane,Water
    标题:Aptamers And Cyclen Compounds And Complexes For The Detection,Monitoring And Treatment Of Cancer
    参考文献:World Intellectual Property Organization]

    59-51-8 + 24424-99-5 = 93000-03-4
    反应条件:1.1 Reagents: Sodium Hydroxide Solvents: 1,4-Dioxane,Water
    标题:Synthesis And Properties Of New Chiral Heterocyclic Peptide Mimetics
    作者:Maity,Prantik
    参考文献:2008]

    59-51-8 + 24424-99-5 = 93000-03-4
    反应条件:1.1 Reagents: Sodium Hydroxide Solvents: Tert-Butanol,Water; Rt; 7 H,35 °C1.2 Reagents: Hydrochloric Acid Solvents: Water; Ph 2
    标题:Design And Synthesis Of Amino-Acid Esters Of 3-(3'-Hydroxy)Butylphthalide
    作者:Zhao,Jiu-Yang; Li,Jun; Zhang,Chao-Hui; Jiang,Tao
    参考文献:Zhongguo Haiyang Daxue Xuebao 日期:2014 卷标:44(1) 页码:68-70]

    59-51-8 + 24424-99-5 = 93000-03-4
    反应条件:1.1 Reagents: Sodium Hydroxide Solvents: Water; 25 °C -> 0 °C1.2 Solvents: 1,4-Dioxane; 0 °C; Overnight,25 °C; 25 °C -> 0 °C1.3 Reagents: Hydrochloric Acid Solvents: Water; Ph 2 - 3
    标题:Enantioselective Deaminative Alkylation Of Amino Acid Derivatives With Unactivated Olefins
    作者:Sun,Shang-Zheng; Cai,Yue-Ming; Zhang,De-Liang; Wang,Jia-Bao; Yao,Hong-Qing; Et Al
    参考文献:Journal Of The American Chemical Society 日期:2022 卷标:144(3) 页码:1130-1137]

    59-51-8 + 24424-99-5 = 93000-03-4 [标题:Reaction Conditions
    标题:Use Of Cyclosquaramide Compounds As Anti-Tumour Agents
    参考文献:United States]

    59-51-8 + 24424-99-5 = 93000-03-4 [标题:Reaction Conditions
    标题:Squaramide-Based Macrocyclic Compounds As Kinase Inhibitors,And Their Preparation And Use In Treatment Of Cancer And Other Diseases
    参考文献:World Intellectual Property Organization]

    = 93000-03-4 [标题:Reaction Conditions
    标题:Simple,Mild,High-Yield Synthesis Of Boc-Amino Acids In Water
    作者:Mathias,Lon J.; Vaidya,Rajeev A.
    参考文献:Journal Of The Mississippi Academy Of Sciences 日期:1984 卷标:29 页码:13-16
📜L-蛋氨酸,二碳酸二叔丁酯置于sodium Hydroxide体系中,用 四氢呋喃 作为反应溶剂,化学反应 17.0H,以87%的收率获得产物2-(叔丁氧基羰基氨基)-4-(甲基硫代)丁酸
参考文献:一种荧光标记的氨基酸及其制备方法和用途
标题:一种荧光标记的氨基酸及其制备方法和用途
摘要:本发明公开了一种荧光标记的氨基酸,具有式i所示的结构:氨基酸分子与式q所示的荧光染料分子之间形成稳定的共价键结合,在血清等检测环境中的稳定性高,生物相容性高,适于细胞内外的蛋白,多肽等生物分子的检测.上述荧光标记的氨基酸,由于荧光染料分子的斯托克斯位移大,同时具有荧光稳定性好,荧光量子产率高,以及成像结果信噪比高的优点.本发明公开了上述荧光标记的氨基酸的制备方法,反应条件温和,操作简单,反应的选择性高,能够制得高产率的荧光标记的氨基酸.

海关参考信息

其他信息查阅

供应商参考报价(招募中)

品牌试剂参考报价(招募中)

实用工具

⚠️全国化工行业净网倡议书
📋制造商识别码
📖 海关编码查询
📝MSDS生成器

📌 第三方产品分析报告

✅ COA系统入驻 | 共享模式

主要参考文献

参考标题:The Asymmetric Synthesis Of Amines Via Nickel-Catalyzed Enantioconvergent Substitution Reactions
作者:Ze-Peng Yang,Dylan J. Freas,Gregory C. Fu |发布日期:2021.2.24
摘要:Dialkyl Carbinamines Do Not Provide General Access To Amines Wherein The Two Alkyl Groups Are Of Similar Size (E.G., Ch2R Versus Ch2R1). Herein, We Report Two Mild Methods For The Catalytic Enantioconvergent Synthesis Of Protected Dialkyl Carbinamines, Both Of Which Use A Chiral Nickel Catalyst To Couple An Alkylzinc Reagent (1.1-1.2 Equiv) With A Racemic Partner, Specifically, An α-Phthalimido Alkyl Chloride
📝 需求与反馈
尽可能描述清楚需求与问题信息
×

通知