
专利信息
专利号:CN-102439025-B
优先权日:2008-09-06
标题:RNA Synthesis - Phosphoramidites for reverse synthesis of RNA, and applications in the convenient introduction of ligands, chromophores and modifiers for RNA synthesis at the 3'-end
专利号:CN-102439025-A
优先权日:2008-09-06
标 题:RNA Synthesis - Phosphoramidites for reverse synthesis of RNA, and their application in the convenient introduction of ligands, chromophores and modifiers for RNA synthesis at the 3'-end
专利号:CN-101243065-A
优先权日:2005-06-10
标 题:Intermediates useful in the synthesis of alkylquinoline and alkylquinazoline kinase modulators and related methods of synthesis
专利号:US-6407103-B2
优先权日:1998-04-21
标 题:Indeno [1,2-c] pyrazol-4-ones and their uses
发明人:NUGIEL DAVID A; CARINI DAVID J; DI MEO SUSAN V; YUE EDDY W
权利人:BRISTOL MYERS SQUIBB PHARMA CO
摘要:The present invention relates to the synthesis of a new class of indeno[1,2-c]pyrazol-4-ones of formula (I):that are potent inhibitors of the class of enzymes known as cyclin dependent kinases, which relate to the catalytic subunits cdk1-9 and their regulatory subunits know as cyclins A-H.This invention also provides a novel method of treating cancer or other proliferative diseases by administering a therapeutically effective amount of one of these compounds or a pharmaceutically acceptable salt form thereof. Alternatively, one can treat cancer or other proliferative diseases by administering a therapeutically effective combination of one of the compounds of the present invention and one or more other known anti-cancer or anti-proliferative agents.
专利号:CN-102105454-A
优先权日:2008-07-25
标题:Synthesis of Inhibitors of Type 1 11β-Hydroxysteroid Dehydrogenase
专利号:CN-107556308-B
优先权日:2017-08-11
标题 :Asymmetric Synthesis of 1-Aryl-1H-Pyridin[3,4-b]Indole-3-Carboxylic Acid Methyl Derivatives