CAS: 3117-03-1; 2,5-Dimethoxy-1,4-Benzoquinone

上下游产品

diazomethane 2,5-dihydroxy-1,4-benzoquinone methanol 2,5-diethoxy-[1,4]benzoquinone 2,5-bis(1-aziridinyl)-1,4-benzoquinone 2-methoxy-5-morpholino-[1,4]benzoquinone 1,2,4,5-tetramethoxybenzene 2,5-dichloro-3,6-dimethoxy-1,4-benzoquinone

📜对苯二甲醚置于间氯过氧苯甲酸体系中,用 二氯甲烷 作为反应溶剂,化学反应 24.0H,以11%的收率获得产物2,5-二甲氧基-1,4-苯醌
参考文献:Strukturen Ladungsgestörter Oder Räumlich überfüllter Moleküle,80 [1-3] Strukturänderungen Von P-Benzochinon Durch Donator-Und Akzeptor-Substituenten
标题:Strukturen Ladungsgestörter Oder Räumlich überfüllter Moleküle,80 [1-3] Strukturänderungen Von P-Benzochinon Durch Donator-Und Akzeptor-Substituenten
摘要:本文介绍并讨论了七种二取代或四取代的对苯醌衍生物o=c(Xc=ch)2C=o和o=c(Xc=cx)2C=o的结构,其中取代基x =-och3,-N(Ch2)5,-N(Ch2Ch2)2O,-Cl,-Cn和-⊕n(Hc=ch)2C-N(Ch3)2,并与已发表的取代基为x =-Si(Ch3)3,-C6H5,-N(Ch3)2,-⊕n(Hc=ch)2Cn(Ch3)2,-O⊖和-No2的结构进行比较.根据介绍,利用半波还原电位,几何优化的量子化学计算对取代基扰动以及已知的对苯醌衍生物的结构数据来表征它们的分子基态.结构变化表明了取代基扰动可能如何被合理解释.在定义的类别中-未受扰动,给体,给体/受体和受体扰动中-给体取代的对苯醌通常表现出最大的差异,通常被称为靛蓝畸变.与广泛的半经验计算非常一致,实验确定的所有效应都根据不同的电荷分布进行讨论.关于对生物化学重要性的对苯醌衍生物,这个首次的结构摘要指出了重要的方面.
DOI:10.1515/znb-1996-0201

专利信息

专利号:US-2009093521-A1
优先权日:2005-06-14
标 题 :2, 5-Bis-Diamine [1,4] Benzoquinone-Derivatives
发明人：BOLOGNESI MARIA LAURA; BANZI RITA; MINARINI ANNA; MELCHIORRE CARLO
权利人:BOLOGNESI MARIA LAURA; BANZI RITA; MINARINI ANNA; MELCHIORRE CARLO
摘要:Synthesis of 2,5-bis-diamine-[1,4]benzoquinonic derivatives having the general formula (I), products and intermediates of said synthesis; the synthesis involves the use of p-benzoquinones having the general formula (IX) and diamines having the general formula (XI).

专利号:US-7935686-B2
优先权日:2004-11-03
标 题 :Acyloxyalkyl carbamate prodrugs, methods of synthesis, and use
发明人：GALLOP MARK A
权利人:XENOPORT INC
摘要:Acyloxyalkyl carbamate prodrugs of 3-aminopropylphosphonous acid, 3-aminopropylphosphinic acid, and analogs thereof, pharmaceutical compositions comprising acyloxyalkyl carbamate prodrugs of 3-aminopropylphosphonous acid, 3-aminopropylphosphinic acid, and analogs thereof, methods of making prodrugs of 3-aminopropylphosphonous acid, 3-aminopropylphosphinic acid, and analogs thereof, methods of using prodrugs of 3-aminopropylphosphonous acid, 3-aminopropylphosphinic acid, and analogs thereof and pharmaceutical compositions thereof for treating or preventing diseases or disorders such as spasticity or gastroesophageal reflux disease are disclosed. Acyloxyalkyl carbamate prodrugs of 3-aminopropylphosphonous acid, 3-aminopropylphosphinic acid, and analogs thereof and sustained release oral dosage forms thereof, which are suitable for oral administration, are also disclosed.

专利号:US-7674934-B2
优先权日:2004-08-05
标题:Stabilizers for use in NVP synthesis
发明人：HOEFER FRANK; BRAND ALEXANDRA; BOETTCHER ARND; BAUMANN KATRIN; VOGELSANG REGINA
权利人:BASF AG
摘要:A process for preparing N-alkenyl compounds by reacting the corresponding NH compounds with alkynes in the liquid phase in the presence of a catalyst, wherein the reaction is carried out in the presence of at least one stabilizer, and the use of stabilizers for increasing the selectivity in a process for preparing N-alkenyl compounds by reacting the corresponding NH compounds with alkynes in the liquid phase in the presence of a catalyst.

专利号:US-7566738-B2
优先权日:2004-11-03
标题 :Acyloxyalkyl carbamate prodrugs of sulfinic acids, methods of synthesis, and use
发明人：GALLOP MARK A
权利人:XENOPORT INC
摘要:Acyloxyalkyl carbamate prodrugs of 3-aminopropylsulfinic acid and analogs thereof, pharmaceutical compositions of 3-aminopropylsulfinic acid and analogs thereof, methods of making prodrugs of 3-aminopropylsulfinic acid and analogs thereof, methods of using prodrugs of 3-aminopropylsulfinic acid and analogs thereof, and pharmaceutical compositions thereof for treating or preventing diseases or disorders such as spasticity or gastroesophageal reflux disease are disclosed. Acyloxyalkyl carbamate prodrugs of 3-aminopropylsulfinic acid and analogs thereof and sustained release oral dosage forms thereof, which are suitable for oral administration, are also disclosed.

专利号:EP-1890995-A2
优先权日:2005-06-14
标 题:Synthesis of organic compounds

专利号:US-2008242723-A1
优先权日:2004-11-03
标题 :Acyloxyalkyl carbamate prodrugs of sulfinic acids, methods of synthesis, and use