CAS: 3077-46-1; (2S,3S)-2-Acetamido-3-Methylpentanoic Acid

相似化合物

2256-76-0 54831-20-8 19764-31-9

上下游产品

CAS号73-32-5 L-异亮氨酸 | CAS号19764-31-9 Acetyl-d-allois... | CAS号1509-34-8 L-别异亮氨酸 | CAS号54831-20-8 N-乙酰基-D-(allo)-异亮氨酸

乙酰胺,反-2-丁烯,一氧化碳置于三(三苯基膦)羰基氢化铑,Dicobalt octacarbonyl,氢气体系中,用 乙酸乙酯 用作溶剂,化学反应 4.0H,以34%的收率获得2-乙酰氨基-3-甲基戊酸
参考文献:Syngas Reactions
标题:Syngas Reactions
摘要:The Amidocarbonylation Of Olefin And Aldehyde Substrates Has Been Applied To The Synthesis Of A Variety Of Amidocarboxylic Acids,Including Surface Active Agents (E.G. C-14-C-16 N-Acyl-Alpha-Amino Acids),Specialty Surfactants (Such As The Sarcosinates),Intermediates For Sweeteners (E.G. Aspartame),Food Additives (E.G. Glutamic Acid),And Certain Chelating Agents. Homogeneous Cobalt And Rhodium-Based Catalysts,Modified,For Example,With Sulfoxide And Bidentate Phosphine Ligands,Have Been Tailored To The Synthesis Of Each Individual Class Of Product. Process Studies,Including Examinations Of Reaction Rate,Product Selectivity,As Well As Catalyst Stability,Have Been Undertaken For N-Acetylglycine And Amido Acid Surfactant Syntheses.
Doi:10.1016/0022-328X(91)80164-F

专利信息

专利号:US-9556221-B2
优先权日:2014-06-20
标题:N-acetyl amino acid ESTER derivatives of betulin and preparation method thereof
发明人：WANG YANG; ZHANG SHENG; DING WEIMING; YU TAO; YAN XIUFENG
权利人:UNIV NORTHEAST FORESTRY
摘要:The present invention disclosed N-acetyl amino acid ester derivatives of betulin and the preparation method thereof, the method comprising the steps that in the presence of an alkaline substance, a catalyst and a racemization-inhibitor, the carboxyl group of N-acetyl amino acid is activated by a coupling agent; and then the activated N-acetyl amino acid is reacted with betulin via esterification reaction to obtain the N-acetyl amino acid ester derivative of betulin. The present invention provided a simple synthesis method to synthesize the N-acetyl amino acid ester derivatives of betulin by using betulin as a precursor compound and modifying the molecular structure of betulin. Such structural modification of betulin significantly enhances the anti-tumor activity of the betulin derivatives and therefore has important values.

专利号:US-9567368-B2
优先权日:2013-11-29
标 题:Peptide tyrosinase activators
发明人：HANTASH BASIL M; UBEID ANAN ABU
权利人:ESCAPE THERAPEUTICS INC
摘要:Peptides that increase melanin synthesis are provided. These peptides include pentapeptides YSSWY (SEQ ID NO: 1), YRSRK (SEQ ID NO: 2), and their variants. The peptides may activate the enzymatic activity of tyrosinase to increase melanin synthesis. The pharmaceutical, cosmetic, and other compositions including the peptides are also provided. The methods of increasing melanin production in epidermis of a subject are provided where the methods include administering compositions comprising an amount of one or more peptides effective to increase the melanin production. The methods also include treating vitiligo or other hypopigmentation disorders with compositions including one or more peptides.

专利号:US-2023089723-A1
优先权日:2020-03-06
标 题:Amino acid compositions and methods for muscle and myotube modulation
发明人：COMB WILLIAM; COKOL MURAT; KULKARNI TRIPTI
权利人:AXCELLA HEALTH INC
摘要:This disclosure provides compositions comprising amino acid entities. The disclosure also provides methods for increasing myogenesis, increasing muscle protein synthesis, increasing muscle mass, improving muscle quality or enhancing muscle function comprising administering an effective amount of the compositions to a subject in need thereof.

专利号:CN-112574033-B
优先权日:2020-07-09
标 题:Synthesis method of 1-hydroxy-2,5,8-trimethyl-9-fluorenone