CAS: 136777-48-5; ((1S,4R)-4-(2-Amino-6-(Cyclopropylamino)-9H-Purin-9-yl)Cyclopent-2-En-1-yl)Methanol Hydrochloride
- 英文名称((1S,4R)-4-(2-Amino-6-(Cyclopropylamino)-9H-Purin-9-yl)Cyclopent-2-En-1-yl)Methanol Hydrochloride
- 中文名称阿巴卡韦
- IUPAC名称((1S,4R)-4-(2-amino-6-(cyclopropylamino)-9H-purin-9-yl)cyclopent-2-en-1-yl)methanol hydrochloride
- CAS编号136777-48-5
- MFCD编号:MFCD18427212
- FDA UNII编号:RP0T719KX7
- 分子式:C14H19ClN6O分子量:322.8
- 产品CID: 571238
- 同类组份化合物CAS136470-78-5 (free base)136777-48-5 (HCl)168146-84-7 (succinate)188062-50-2 (sulfate)1446418-48-9 (hydroxyacetate)384380-52-3 (carboxylate)
- 产品分类原料药 → 人工合成抗感染类药 → 抗病毒类药
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主要参考文献
1: Fantauzzi A, Floridia M, Falasca F, Spanedda P, Turriziani O, Vullo V, Mezzaroma I. Backbone switch to abacavir/lamivudine fixed-dose combination: implications for antiretroviral therapy optimization. New Microbiol. 2015 Oct 20;38(4). [Epub ahead of print] Abacavir, zidovudine, or stavudine as paediatric tablets for African HIV-infected children (CHAPAS-3): an open-label, parallel-group, randomised controlled trial. Lancet Infect Dis. 2015 Oct 5. pii: S1473-3099(15)00319-9. doi: 10.1016/S1473-3099(15)00319-9. [Epub ahead of print] doi: 10.1016/j.ijbiomac.2015.09.015. [Epub ahead of print] doi: 10.1016/j.bmcl.2015.07.054. Epub 2015 Jul 26. doi: 10.1016/j.reprotox.2015.07.070. Epub 2015 Jul 10. doi: 10.1179/1528433614Z.0000000017. Epub 2015 Jul 2.
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