CAS: 99349-68-5; (3-Acrylamidophenyl)Boronic Acid

上下游产品

3-Aminophenylboronic acid acrylic acid acryloyl chloride 3-aminophenylboronic acid hydr°Chloric salt N-(3-(5-chloro-2-((4-morpholinophenyl)amino)pyrimidin-4-yl)phenyl)acrylamide N-(3-(5-chloro-2-((4-(4-methylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)phenyl)acrylamide N-(3-(2-chloro-5-(phenylamino)pyrimidin-4-yl)phenyl)acrylamide N-(3-(6-chloro-1-(terahydro-2H-pyran-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)phenyl)acrylamide

3-氨基苯硼酸,丙烯酰氯置于碳酸氢钠体系中,用 四氢呋喃,水 作为反应溶剂,化学反应 4.5H,反应生成 3-丙烯酰胺基苯硼酸
参考文献:β-内酰胺酶印迹反应水凝胶治疗抗药性细菌
标题:β-内酰胺酶印迹反应水凝胶治疗抗药性细菌
摘要:抗生素在感染的治疗和预防中起着重要的作用.但是,现在耐药菌的流行威胁着抗生素的有效性.此外,抗生素的滥用和环境中的残留物会导致严重的健康问题.在这项研究中,通过使用细菌产生的用于使抗生素失活的β-内酰胺酶作为模板分子,制备了一种具有刺激反应的印迹水凝胶.印迹的水凝胶最初可以捕获耐药细菌分泌的β-内酰胺酶,从而使细菌对抗生素敏感.杀菌处理后,温度刺激可逆地消除水凝胶上的"印迹部位",从而导致β-内酰胺酶重新活化,降解抗生素残留.
DOI:10.1002/anie.201600205

专利信息

专利号:US-2023212216-A1
优先权日:2019-12-20
标 题:Synthesis of lactone derivatives and their use in the modification of proteins
发明人：MORRIS ALEXANDER REDFERN; SUTOV GRIGORIJ; BRUNE KARL DIETRICH
权利人:GENIE BIOTECH UK LTD
摘要:Site-specific modifications of proteins are desirable in biotechnological applications such as biopharmaceuticals, immunotherapy, vaccines, and are useful in chemical biology. Gluconoylation is a non-enzymatic, covalent, post-translational modification commonly observed on N-terminal His-Tags bearing proteins. We synthesized glucono-1,5-lactone derivatives, including azido variants for selective acylation. High yield acylation is achieved by simply mixing derivatives with target protein amidst diverse conditions of temperatures, aqueous buffers, excipients, or complex cell lysate.

专利号:US-7728088-B2
优先权日:2002-08-06
标题 :Synthesis of statistical microgels by means of controlled radical polymerisation
发明人：DESTARAC MATHIAS; BAVOUZET BRUNO; TATON DANIEL
权利人:RHODIA OPERATIONS
摘要:The invention relates to a method of preparing statistical microgels. The inventive method comprises a step involving the radical polymerisation of a composition containing: at least one monoethylenically-unsaturated monomer, at least one multiethylenically-unsaturated monomer, a free radical source and a control agent. The invention also relates to first generation microgels thus prepared and all the compounds resulting from said microgels (next-generation microgels).

专利号:US-2006106178-A1
优先权日:2002-08-06
标题:Synthesis of statistical microgels by means of controlled radical polymerisation

专利号:AU-2005248117-B2
优先权日:2004-05-14
标题 :Synthesis of copolymers in the form of a mikto star by controlled radical polymerization

专利号:AU-2005248117-A1
优先权日:2004-05-14
标 题:Synthesis of copolymers in the form of a mikto star by controlled radical polymerization

专利号:US-2008114128-A1
优先权日:2004-05-14
标 题 :Synthesis of Copolymers in the Form of a Mikto Star by Controlled Radical Polymerization