CAS: 613-13-8; Anthracen-2-Amine
该化合物是属于多环芳烃(PAHs)类的有机化合物,其特征是附于炭疽结构的氨基组(-NH2),该组由三根有引信的苯环组成,通常在室温下是固体,呈现一种特殊的暗色. 2-氨乙烷以其潜在的诱变和致癌特性而著称,使其成为环境和健康研究的一个课题.该组在水中相对溶解,但在乙醇和丙酮等有机溶剂中可溶解.该组可因芳香环和氨基组的存在而发生各种化学反应,包括电除害替代和氧化.其应用范围扩大到有机合成和化学研究中的试剂,特别是在与DNA相互作用有关的研究中和诱变机制中.在处理该物质时,安全防范措施由于其毒性特征至关重要.
- 英文名称Anthracen-2-Amine
- 中文名称2-氨基蒽
- IUPAC名称anthracen-2-amine
- 其它别名2-Anthracenamine; 2-Anthramine; Ycsbaljagzkwff-Uhfffaoysa-; Anthracene, 2-Amino; .Beta.-Aminoanthracene; Inchi=1/c14H11N/c15-14-6-5-12-7-10-3-1-2-4-11(10)8-13(12)9-14/h1-9H,15H2
- CAS编号613-13-8
- MFCD编号:MFCD00003582
- EINECS号:210-330-9
- FDA UNII编号:8240818JGU
- 分子式:C14H11N分子量:193.24
- 产品CID: 1594854
- 产品分类化学试剂 → 有机试剂 → 三环化合物
物理性质
- 熔点238-241 °C (文献)
- 沸点319.47°C (粗估)
- 闪点229 °C
- 密度1.1061 (粗估)
- pKa:4.32±0.30(预测)
- PSA:26.02
- LogP:4.1564
- 折射率1.5850 (估算)
- 蒸汽压4.52E-07 mmHg at 25 °C
- 溶解性Chloroform (Very Slightly), Dichloromethane (Slightly), DMSO (Slightly)
- 敏感性2-AMINOANTHRACENE may be unstable with prolonged exposure to air and light. Solutions of this chemical should be stable for 24 hours under normal lab conditions. (NTP, 1992)
- 外观形态乙醇中析出的黄色小叶状晶体固体
- 储存条件请置于阴暗处, 惰性气氛中,室温
- 产品应用该化合物用于反应剂:通过5-Α-胆固醇-3-1和芳香甲酰胺的多成分环凝反应,通过多成分凝聚反应,产生凝聚性沥青化合物.
MSDS等安全信息
欧盟法规
ECHA物质C&L通报REACH预注册上下游产品
acetamide 2-hydroxyanthracene 2-aminoanthraquinone methanol 2-anthraceneis°Cyanate 1-phenylazo-[2]anthrylamine di-[2]anthryl-amine 2-(acetylamino)anthracene合成工艺路线路线简述
📜2-叠氮蒽 以 四氢呋喃,水 作为反应溶剂,化学反应 2.0H,以61%的收率获得产物2-氨基蒽
参考文献:触发发射,可快速检测大斯托克斯位移陪伴下的硫化氢分子
标题:触发发射,可快速检测大斯托克斯位移陪伴下的硫化氢分子
摘要:当前手稿演示发展的反应为基础的"接通"绿色发光的分子探针(p4),用于快速检测h的2在生理条件s.发现该探针显示出低检测限(1.19μm),以及高选择性,大斯托克斯位移和非常好的量子效率.在理论上,还使用密度泛函理论计算对探针光学行为的变化进行了仔细检查,这些计算与光物理结果非常吻合.考虑到对大型stokes染料用于传感应用的需求,主要是因为它们具有特殊的光物理性质,并且由于报告的数量非常有限,因此具有110 Nm Stokes位移的本探头是用于h 2的大型stokes染料的好选择在生理条件下的s识别.
DOI:10.1016/j.Jphotochem.2018.11.011
海关参考信息
- 2902902000-精萘
- 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-2024207302-A1
优先权日:2021-04-01
标 题 :Antiviral compounds, methods for the manufacturing of compounds, antiviral pharmaceutical composition, use of the compounds and method for the oral treatment of coronavirus infection and related diseases thereof
发明人：CALIXTO JOãO BATISTA; RABI NALLAR JAIME ALBERTO; LOPES E SOUZA THIAGO MORENO
权利人:CALIXTO JOAO BATISTA; RABI NALLAR JAIME ALBERTO; LOPES E SOUZA THIAGO MORENO
摘要:The present invention relates to antiviral compounds selected from cytokinins, their nucleosides and nucleotide analogs, and their prodrugs as inhibitors of viral RNA synthesis, or their salts, solvates, derivatives, or even combinations of aforementioned compounds, for prophylactic treatment, curative (therapeutic) or mitigative coronavirus infection, represented by human and veterinary coronavirus, SARS-COV-2 and MHIV, and for the treatment of individuals potentially exposed to COVID-19. The present invention also comprises the methods for the manufacturing of such compounds, the antiviral pharmaceutical composition containing the compounds of the invention, as well as the use of the compounds, combinations of compounds, and method for the prophylactic, curative (therapeutic) or mitigative treatment of coronavirus infection, represented by coronavirus, in especial SARS-COV-2 and of patients with COVID-19, individual infected with SARS-COV-2 or potentially exposed to this virus. The antiviral activity of the compounds of this invention against SARS-COV-2 was greatly enhanced by inhibiting the 3′-5′-exonuclease. Synergistic results of the compounds according to the present invention were obtained from the combination with repurposed drugs.
专利号:WO-9746915-A1
优先权日:1996-06-06
标 题 :Metal ion reduction of aminochromatic chromophores and their use in the synthesis of low metal bottom anti-reflective coatings for photoresists
专利号:EP-0904568-B1
优先权日:1996-06-06
标题 :Metal ion reduction of aminoaromatic chromophores and their use in the synthesis of low metal bottom anti-reflective coatings for photoresists
发明人：RAHMAN M DALIL; HANNIGAN TIMOTHY T; LYNCH THOMAS J
权利人:CLARIANT FINANCE BVI LTD
专利号:JP-2000512394-A
优先权日:1996-06-06
标 题 :Method for reducing metal ions in aminochromatic color-forming materials and use of same in the synthesis of bottom metal anti-reflective coating materials containing little metal for photoresists
专利号:EP-0904568-A1
优先权日:1996-06-06
标题:Metal ion reduction of aminochromatic chromophores and their use in the synthesis of low metal bottom anti-reflective coatings for photoresists
专利号:CN-1221497-A
优先权日:1996-06-06
标题 :Reduction of metal ion content of amino-colored chromophores and their use in the synthesis of low metal content antireflective primers for photoresists
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
合成参考文献
摘要:NIOSH; National Occupational Exposure Survey (NOES) (1983)
摘要:Korfmacher WA et al; Science 207: 763-5 (1980)
摘要:Weast, R.C. (ed.) Handbook of Chemistry and Physics. 69th ed. Boca Raton, FL: CRC Press Inc., 1988-1989., p. C-78
参考文献:10.1002/(sici)1098-2280(1999)33:4<325::aid-em10>3.0.co;2-e
摘要:Umbuzeiro-Valent G, Roubicek DA, Haebisch EM. Mutagenic and antimutagenic evaluation of the juice of the leaves of Bryophyllum calycinum (Kalanchoe pinnata), a plant with antihistamine activity. Environ Mol Mutagen. 1999;33(4):325–7. doi: 10.1002/(sici)1098-2280(1999)33:4<325::aid-em10>3.0.co;2-e.
参考文献:10.1016/s0300-483x(99)00034-7
摘要:Marczylo T, Ioannides C. Evidence for the presence of a microsomal NADH-dependent enzyme system that can bioactivate aromatic amines in the liver of rats and mice. Toxicology. 1999 Jun 15;134(2-3):127–41. doi: 10.1016/s0300-483x(99)00034-7.
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