CAS: 60902-45-6; Nonyltriphenylphosphonium Bromide

相似化合物

15510-55-1 25791-20-2 13423-48-8

上下游产品

1-Bromononane triphenylphosphine 1-Benzyloxy-3-(1,1-dimethyl-2-undecenyl)-benzol methyl cis-13-d°Cosenoate brassidic acid methyl ester (R)-6-((Z)-(S)-1-Benzyloxy-undec-2-enyl)-tetrahydro-pyran-2-one

1-溴壬烷,三苯基膦 反应 2.5H,反应生成 (1-壬基)三苯基溴化磷
参考文献:天然存在的非丙酮产乙酸原的拟态研究:非thf类似物导致对人类肿瘤细胞的显着选择性细胞毒性.
标题:天然存在的非丙酮产乙酸原的拟态研究:非thf类似物导致对人类肿瘤细胞的显着选择性细胞毒性.
摘要:开发了一类天然存在的非丙酮产乙酸原素的结构简化的类似物,其中一些非thf类似物对肿瘤细胞系显示出显着的细胞毒性,并且在人肿瘤细胞和正常细胞之间具有非常好的选择性.由于去除了天然模板上带有thf环的手性中心,合成路线大大缩短.这种简化还提供了通过组合策略对这些模拟物进行并行综合的途径.chiron方法通过容易获得的手性结构单元6A和/或6B(由l-抗坏血酸或d-甘露醇依次制得,而丁烯内酯中的一个由手性构成)引入了其余的立体异构中心(位于醚键的α位).片段取自l-乳酸盐.所有四个非对映异构体非thf类似物2A-2D对hct-8细胞系均表现出显着活性,并且在针对ht-29细胞系进行测试时发现了更好的分化.还发现,丁烯内酯和乙二醇亚基均在针对肿瘤细胞系的细胞毒性中起重要作用,而丁烯内酯部分上的10-取代的羟基和甲基的绝对构型对其活性不太重要.
DOI:10.1002/chem.200390021

专利信息

专利号:US-3682970-A
优先权日:1969-03-27
标 题:Production of unsaturated carbocyclic ketones
发明人：HENRICK CLIVE A; EDWARDS JOHN A; FRIED JOHN H
权利人:SYNTEX CORP
摘要:Preparation of Alpha , Beta -unsaturated carbocyclic ketones by reacting a methylene or methine phosphonium ylid with a delta keto carboxylic acid ester, anhydride or acyl halide. The reaction is useful for producing intermediates for synthesis of known steroids having estrogenic, progestational, or anabolic activity, for example.

专利号:US-4432906-A
优先权日:1981-09-14
标 题 :Inhibitors of SRS-synthesis
发明人：COHEN NOAL; WEBER GIUSEPPE
权利人:HOFFMANN LA ROCHE
摘要:Methyl derivatives of arachidonic acid and intermediates thereto have been synthesized. These derivatives are inhibitors of SRS-A synthesis and are useful for treating and preventing allergic reactions.

专利号:US-2008214386-A1
优先权日:2004-03-01
标题:Catalyst for Cyclic Carbonate Synthesis
发明人：TAKAHASHI TOSHIKAZU; WATAHIKI TSUTOMU; YASUDA HIROYUKI; SAKAKURA TOSHIYASU
权利人:TAKAHASHI TOSHIKAZU; WATAHIKI TSUTOMU; YASUDA HIROYUKI; SAKAKURA TOSHIYASU
摘要:Provided are a solid catalyst which gives a cyclic carbonate at a high yield and a high selectivity, which is stable and which may be readily separated after reaction; and a method of industrially advantageous, inexpensive and safe production of a cyclic carbonate by the use of the catalyst. The catalyst contains an inorganic solid substance having a surface modified with an ionic substance containing a Group 15 element; or contains an ionic substance containing a Group 15 element, and an inorganic solid substance. The modifying group for surface modification of an inorganic solid substance is an ionic substance containing a Group 15 element. The ionic substance containing a Group 15 element is at least one substance selected from organic phosphonium salts, organic ammonium salts, organic arsonium salts and organic antimonium salts.

专利号:EP-4200609-B1
优先权日:2020-08-20
标题 :An assay for measuring binding affinity for cardiolipin of biologically active compounds
发明人：ARSENJANS PAVELS; DIMITRIJEVS PAVELS
权利人:LATVIAN INST ORGANIC SYNTHESIS

专利号:RU-1839671-C
优先权日:1989-05-12
标 题 :Method of synthesis of 3,5,6-trichloropyridine-2-ol, 2,2,4-trichloro-4- -cyanobutanoyl chloride, and 3,3,5,6-tetrachloro-3,4-dihydropyridine-2-one