CAS: 500-89-0; 1-(4-Butoxyphenyl)-3-[4-(Dimethylamino)Phenyl]Thiourea

该化合物是具有硫尿亚功能组特征的有机化合物,该功能组由硫磺原子结为碳原子,该原子也同时与氧原子同时存在.该化合物有两种不同的芳香环:一个含有丁氧基的环,另一个含有二甲基氨基组,有助于其溶解性和再活性.丁氧基组的存在增强了其缺水特性,而二甲基氨基组则可以参与各种化学反应,包括质子反应,使该化合物在染料,制药等各种应用中或作为有机合成的中间体中具有潜在用途.该化合物一般在室内温度下是固体的,在标准条件下可能具有中等稳定性,尽管在处理时应谨慎处理与硫尿衍生物有关的潜在毒性.在实验室环境中与该物质打交道时应采取适当的安全措施.

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上下游产品

CAS号99-98-9 对氨基-N,N-二甲基苯胺 | CAS号3460-50-2 1-丁氧基-4-异硫氰酰基苯 | CAS号4344-55-2 4-丁氧基苯胺

合成工艺路线路线简述

    📜4-丁氧基苯胺 反应生成 硫安布新
    参考文献:Di-Phenyl-Thioureas
    标题:Di-Phenyl-Thioureas

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    专利信息


    专利号:CN-102862984-A
    优先权日:2012-09-25
    标 题:Excess carbon disulfide recovery device and recovery method in the synthesis process of rubber vulcanization accelerator diphenylthiourea

    专利号:CN-102350349-A
    优先权日:2011-08-29
    标 题 :Catalyst used in the oxygen oxidation synthesis production process of accelerator diphenylguanidine and its preparation method

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    ✅ COA系统入驻 | 共享模式

    主要参考文献


    1: Smith TC, Richardus JH. Relapse rates in patients treated with dapsone monotherapy and combinations of dapsone and thiambutosine, thiacetazone, isoniazid and streptomycin in the pre-MDT era. Int J Lepr Other Mycobact Dis. 1994 Sep;62(3):353-8. 83(5):447-54. doi: 10.1080/00034983.1989.11812371. 10(2):71-5. 56(20):1364-70. German. 53(2):278-84. 49(4):324-6. 49(2):101-13. 1(6106):133-6. doi: 10.1136/bmj.1.6106.133.
    9: Waters MF, Pearson JM, Rees RJ. Drug resistant leprosy--a comparison between proven dapsone and proven thiambutosine resistance. Int J Lepr Other Mycobact Dis. 1976 Jan-Jun;44(1-2):152-3. 44(1-2):123. 111(5):651-5. doi: 10.1164/arrd.1975.111.5.651. 100(1188):178-81. doi: 10.1039/an9750000178. 42(5):667-72.
    14: Garrod JM, Ellard GA. Appearance of resistance during prolonged treatment of leprosy with Thiambutosine. Lepr Rev. 1968 Jul;39(3):113-7. doi: 10.5935/0305-7518.19680021. 37(1):47-8. doi: 10.5935/0305-7518.19660011. 37(1):17-22. doi: 10.5935/0305-7518.19660003.

    合成参考文献


    摘要:Guru Prasad AR, Rao VS. Polarographic determination of certain cephalosporins in pharmaceutical preparations. Res Pharm Sci. 2010 Jan;5(1):57–63.
    摘要:Smith TC, Richardus JH. Relapse rates in patients treated with dapsone monotherapy and combinations of dapsone and thiambutosine, thiacetazone, isoniazid and streptomycin in the pre-MDT era. Int J Lepr Other Mycobact Dis. 1994 Sep;62(3):353–8.
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