CAS: 486-47-5; Ethaverine

📜1-(3',4'-Diethoxy-Benzyl)-6,7-Diethoxy-3,4-Dihydro-Isoquinoline置于palladium On Activated Charcoal,Diisopropylbenzene体系中,化学反应生成 乙罂粟碱依沙维林
参考文献:Preparation Of Some Homologs Of Papaverine
标题:Preparation Of Some Homologs Of Papaverine
摘要:
DOI:10.1021/ja01166A009

专利信息

专利号:US-4425354-A
优先权日:1977-08-26
标题:Imidazole derivatives and salts thereof, their synthesis, and intermediates, and pharmaceutical formulations
发明人：THOROGOOD PETER B
权利人:BURROUGHS WELLCOME CO
摘要:1-Substituted-imidazoles of the formula: (I) in which A is selected from the group consisting of straight or branched, saturated or unsaturated, acyclic hydrocarbon radicals of from 1 to 3 carbon atoms and R is wherein n is an integer which is at least 1, and the or each Q substituent, which when n is greater than 1 may be the same or different, is selected from a saturated alkyl group of from 1 to 4 carbon atoms or an unsaturated alkyl group of from 2 to 4 carbon atoms, with the proviso that when A is unsaturated Q may also be selected from alkoxy of from 1 to 4 carbon atoms; halo; trihalomethyl; hydroxy; carboxyl; a salt of such a carboxyl group; carboalkyloxy; carboaryloxy; carboarylalkyloxy; -NR6R7 or -CONR6R7; in which R6 and R7 may be the same or different and are hydrogen or alkyl of from 1 to 4 carbon atoms; the 1-substituted-imidazole being the free base or an acid addition salt thereof. Methods of preparing the 1-substituted-imidazoles are also provided. The imidazoles have pharmacological properties that make them of use in the treatment of thromboembolic disorders, shock and angina pectoris.

专利号:WO-2025022063-A1
优先权日:2023-07-21
标 题:Alcoholic extract of the flowering aerial parts of tansy, tanacetum vulgare, method for obtaining same, and cosmetic composition containing same
发明人：COCANDEAU VINCENT; LERISSON ANNIE
权利人:CHANEL PARFUMS BEAUTE
摘要:The invention relates to an extract of the flowering aerial parts of tansy, Tanacetum vulgare, the method for obtaining same, and the cosmetic composition containing same, as well as the different cosmetic uses thereof. It has anti-ageing cosmetic properties that are similar to the properties of retinol but without the drawbacks associated with retinol. Specifically, it leads to a significant increase in epidermal thickness, strengthens the barrier function by enhancing Loricrin synthesis, and promotes tissue renewal. It has also been proven to reduce the progression of skin ageing.

专利号:EP-0019223-A1
优先权日:1979-05-09
标 题 :Optically active hydantoin derivatives, their synthesis, pharmaceutical formulations containing them, and intermediates
发明人：WHITTAKER NORMAN
权利人:WELLCOME FOUND
摘要:Compounds of formula (I)n having only two optically active centres, may exist as four isomers, each of which may be prepared by resolving a racemic amino-diester intermediate in the preparation thereof. The racemic amino-diester is selectively hydrolysed to the corresponding mono-ester which is acylated and subsequently selectively deacylated to produce the resolved mono-ester. n Isomers of compounds of formula (I) having a particular configuration are biologically more active than the corresponding isomers having other configurations and are useful in medicine, either as the raw compound or in a pharmaceutical formulation, for example in inhibiting platelet aggregation.

专利号:US-7993390-B2
优先权日:2002-02-08
标 题:Implantable or insertable medical device resistant to microbial growth and biofilm formation
发明人：MILLER KATHLEEN M; BUCAY-COUTO WEENNA; LI JIANMIN
权利人:BOSTON SCIENT SCIMED INC
摘要:Disclosed are implantable or insertable medical devices that provide resistance to microbial growth on and in the environment of the device and resistance to microbial adhesion and biofilm formation on the device. In particular, the invention discloses implantable or insertable medical devices that comprise at least one biocompatible matrix polymer region, an antimicrobial agent for providing resistance to microbial growth and/or a microbial adhesion/biofilm synthesis inhibitor for inhibiting the attachment of microbes and the synthesis and accumulation of biofilm on the surface of the medical device. Also disclosed are methods of manufacturing such devices under conditions that substantially prevent preferential partitioning of any of said bioactive agents to a surface of the biocompatible matrix polymer and substantially prevent chemical modification of said bioactive agents.

专利号:CN-113135838-B
优先权日:2021-04-25
标 题:A kind of method of continuous flow synthesis benserazide hydrochloride