CAS: 29106-51-2; (2R,2'R,3S,3'R,4S)-2,2'-Bis(3,4-Dihydroxyphenyl)-[4,8'-Bichroman]-3,3',5,5',7,7'-Hexaol

上下游产品

4 3'-O-gallatepr°Cyanidin B4 3'-O-gallate 8)-catechin-(4α8)-epicatechinepicatechin-(4β*8)-catechin-(4α*8)-epicatechin phenylmethanethiol 8)-epicatechin-(4β->S)-benzylthioethercatechin-(4α-8)-epicatechin-(4β-S)-benzylthioetherpr°Cyanidin °Ctamethyl ether Catechin-(4alpha-8)-epigall°C atechin-3-gallate (2R,3R)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-1[2H]-benzopyran-3,5,7-triol catechin

📜花旗松素置于silver Tetrafluoroborate Sodium Tetrahydroborate,溶剂黄146体系中,用 四氢呋喃,乙醇 用作溶剂,化学反应 13.0H,反应生成原花青素b4
参考文献:Oligomeric Flavanoids. Part 27. Interflavanyl Bond Formation In Procyanidins Under Neutral Conditions
标题:Oligomeric Flavanoids. Part 27. Interflavanyl Bond Formation In Procyanidins Under Neutral Conditions
摘要:Dimethyl(Methylthio)Sulfonium Tetrafluoroborate (Dmtsf) And Silver Tetrafluoroborate (Agbf4) Activate The Ci-S Bond In The Lt-Thioethers Of Flavan-3-Ols Toward Carbon Nucleophiles To Permit Formation Of The Interflavanyl Bond In Procyanidins Under Neutral Conditions. (C) 1998 Published By Elsevier Science Ltd. All Rights Reserved.
Doi:10.1016/s0040-4020(98)00454-2

专利信息

专利号:US-9133176-B2
优先权日:2002-02-15
标题:Isolation, purification and synthesis of procyanidin B2 and uses thereof
发明人：CASTILLO GERARDO; NGUYEN BETH; CHOI PAULA; LARSEN LESLEY; LORIMER STEPHEN; SNOW ALAN
权利人:CASTILLO GERARDO; NGUYEN BETH; CHOI PAULA; LARSEN LESLEY; LORIMER STEPHEN; SNOW ALAN; PROTEOTECH INC
摘要:Methods for the synthesis, isolation, and purification of procyanidin B2 are disclosed. The synthetic methods utilize epicatechin as a starting material and produce procyanidin B2 in high yields. The isolation methods extract procyanidin B2 from a sample of bark powder from plant matter of the genus Uncaria . The isolated and/or synthesized procyanidin B2 is used to treat amyloid disease, such as Alzheimer's disease and Parkinson's disease as well as improve cognitive performance and increase learning and memory in Alzheimer's patients. Pharmaceutical compositions containing the synthesized and/or isolated procyanidin B2 are also disclosed.

专利号:EP-1921076-A1
优先权日:2002-10-11
标题:systhesis of procyanidin B2
发明人：CASTILLO GERARDO M; NGUYEN BETH P; CHOI PAULA Y; LARSEN LESLEY; LORIMER STEPHEN D; SNOW ALAN D
权利人:PROTEOTECH INC
摘要:Methods for the synthesis of procyanidin B2 are disclosed. The synthetic methods utilize epicatechin as a starting material and produce procyanidin BZ in high yields.

专利号:CA-2499549-C
优先权日:2002-10-11
标题:Isolation, purification and synthesis of procyanidin b2 and uses thereof

专利号:US-2008306142-A1
优先权日:2002-02-15
标题 :Isolation, purification and synthesis of procyanidin B2 and uses thereof

专利号:US-2008306286-A1
优先权日:2002-10-11
标题 :Isolation, Purification and Synthesis of Procyanidin B2 and Uses Thereof

专利号:US-2004260076-A1
优先权日:2002-10-11
标题 :Isolation, purification and synthesis of procyanidin B2 and uses thereof