CAS: 132951-90-7; 2,4,6-Trihydroxy-5-((R)-1-((1Ar,4R,4Ar,7S,7As,7Br)-4-Hydroxy-1,1,4,7-Tetramethyldecahydro-1H-Cyclopropa[e]Azulen-7-yl)-3-Methylbutyl)Isophthalaldehyde
该化合物是一个复杂的有机化合物,其特点是多种氢氧基组和藻类功能;三个氢氧(-OH)组的存在有助于其作为多酚化合物的潜力,可能具有抗氧化性;该化合物的结构包括二氯丁二烯丁二酰胺,表明存在两个可以参与各种化学反应的甲酰二类,如凝聚或聚合;环丙烷和丙烯框架产生的复杂的双环结构表明有机合成和药用化学的潜在应用;此外,(1R)和(1aR,4R, 4R,7S,7S,7bR)标语表明的立体化学学表明,该化合物可能具有特定的空间安排,可能影响其生物活动和相互作用;总体而言,该混合物独特的结构特征使它成为对各种化学和制药应用进行进一步研究的课题.
- 英文名称2,4,6-Trihydroxy-5-((R)-1-((1Ar,4R,4Ar,7S,7As,7Br)-4-Hydroxy-1,1,4,7-Tetramethyldecahydro-1H-Cyclopropa[e]Azulen-7-yl)-3-Methylbutyl)Isophthalaldehyde
- 中文名称大果桉醛 A
- IUPAC名称2,4,6-trihydroxy-5-((R)-1-((1aR,4R,4aR,7S,7aS,7bR)-4-hydroxy-1,1,4,7-tetramethyldecahydro-1H-cyclopropa[e]azulen-7-yl)-3-methylbutyl)isophthalaldehyde
- 其它别名(1Ar,4Aβ,7Aα,7Bβ)-Decahydro-1,1,4,7-Tetramethyl-7α-[(R)-2,4,6-Trihydroxy-3,5-Diformyl-α-(2-Methylpropyl)Benzyl]-1H-Cycloprop[e]Azulen-4β-Ol; 2,4,6-Trihydroxy-5-[(1R)-1-[(1Aβ,4R,4Aβ,7Aα,7Bβ)-1,1,4,7-Tetramethyl-4β-Hydroxydecahydro-1H-Cyclopropa[e]Azulene-7α-Yl]-3-Methylbutyl]Isophthalaldehyde; Macrocarpal A; 1,3-Benzenedicarboxaldehyde, 5-[(1R)-1-[(1Ar,4R,4Ar,7S,7As,7Br)-Decahydro-4-Hydroxy-1,1,4,7-Tetramethyl-1H-Cycloprop[e]Azulen-7-Yl]-3-Methylbutyl]-2,4,6-Trihydroxy-; 5-[(1R)-1-[(1Ar,4R,4Ar,7S,7As,7Br)-4-Hydroxy-1,1,4,7-Tetramethyl-1A,2,3,4A,5,6,7A,7B-Octahydrocyclopropa[h]Azulen-7-Yl]-3-Methylbutyl]-2,4,6-Trihydroxybenzene-1,3-Dicarbaldehyde
- CAS编号132951-90-7
- MFCD编号:MFCD20260953
- 分子式:C28H40O6分子量:472.62
- 产品CID: 495650
- 产品分类天然产物 → 倍半萜
物理性质
- 沸点535.7±50.0 °C at 760 mmHg
- 闪点291.8 °C
- 密度3>1.201 g/ cm3
- PSA:115.06
- LogP:5.4076
- 折射率1.595
- 蒸汽压2.63E-12 mmHg at 25 °C
- 溶解性Soluble In Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,Etc.
- 外观形态黄色粉末
- 产品应用该化合物是一种从EUCALYPTUS MAGCARPA叶叶中分离出来的抗菌剂;它抑制了BACILLUS SUBTILIS PCI219(最低抑制浓度 < 0.2 微米)和FD209P(最低抗菌浓度=0.4 微M)的生长.
MSDS等安全信息
合成工艺路线路线简述
海关参考信息
- 2902600000-乙苯
2902700000-异丙基苯
2905122000-异丙醇
2905143000-叔丁醇 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-2002165207-A1
优先权日:2001-05-02
标题 :Compositions and methods for the treatment of diabetic neuropathy
发明人：ROSENBLOOM RICHARD
摘要:Compositions and a method for the treatment of diabetic neuropathy is disclosed. The compositions comprise a mixture of a compound that promotes synthesis of nerve growth factor, an aldose reductase inhibitor and an antioxidant, optionally formulated in a pharmaceutically acceptable carrier. This combination of active agents provides significant, effective relief of the symptoms of diabetic neuropathy, as well as at least partial recovery of lost neurological function in some cases. In addition, the compositions of the present invention, when used in effective amounts to treat diabetic neuropathy, do not exhibit the severe side effects of many prior art compositions proposed for treatment of this ailment. n In a second aspect, a method for the administration of a composition in accordance with the present invention for the treatment of diabetic neuropathy is disclosed. In the method, an effective amount of the composition of the invention is administered on a regular basis over a period of time sufficient to provide the beneficial effects of relief from the symptoms of diabetic neuropathy, as well as at least some recovery of the damaged nerve tissues.
