CAS: 132172-61-3; N,N,N-Trimethyl-2,3-Bis(Oleoyloxy)Propan-1-Aminium Chloride

相似化合物

104872-42-6 104162-48-3 252769-92-9

上下游产品

dichloromethane (+/-)-N,N-dimethyl-N-[2,3-bis(9-(Z)-°Ctadecanoyloxy)propyl]amine methylene chloride cis-°Ctadecenoic acid

油酸置于4-二甲氨基吡啶,四甲基氯化铵,盐酸-N-乙基-N'-(3-二甲氨基丙基)碳二亚胺体系中,用 乙醇,氯仿,丙酮 用作溶剂,化学反应 5.0H,反应生成(2,3-二油氧基丙基)三甲基氯化铵
参考文献:カチオン性脂質の製造方法
标题:カチオン性脂質の製造方法
摘要:提供一种工业生产高纯度阳离子脂质的方法,无需特殊设备.将由式(1)表示的阳离子脂质与含x-的四烷基铵盐在有机溶剂中混合,在析出的碘化四烷基铵盐中分离出滤液后,通过浓缩滤液使碘化四烷基铵盐析出,从而获得由式(2)表示的阳离子脂质.

专利信息

专利号:US-2004242897-A1
优先权日:2002-07-31
标题 :Universal support media for synthesis of oligomeric compounds
发明人：GUZAEV ANDREI P; MANOHARAN MUTHIAH
摘要:Compounds for the synthesis of oligomeric compounds, particularly oligonucleotides and oligonucleotide mimetics, are provided. In addition, methods for functionalizing a support medium with a first monomeric subunit and methods for the synthesis of oligomeric compounds utilizing the novel compounds bound to support media are provided.

专利号:WO-2004011474-A1
优先权日:2002-07-31
标题:Universal support media for synthesis of oligomeric compounds
发明人：GUZAEV ANDREI P; MANOHARAN MUTHIAH; RAVIKUMAR VASULINGA T; KUMAR RAJU K
权利人:ISIS PHARMACEUTICALS INC; GUZAEV ANDREI P; MANOHARAN MUTHIAH; RAVIKUMAR VASULINGA T; KUMAR RAJU K
摘要:Compounds for the synthesis of oligomeric compounds, particularly oligonucleotide and oligonucleotide mimetics, are provided. In addition, methods for functionalizing a support medium with a first monomeric subunit and methods for the synthesis of oligomeric compounds utilizing the novel compounds bound to support media are provided.

专利号:US-6653468-B1
优先权日:2002-07-31
标 题 :Universal support media for synthesis of oligomeric compounds
发明人：GUZAEV ANDREI P; MANOHARAN MUTHIAH
权利人:ISIS PHARMACEUTICALS INC
摘要:Compounds for the synthesis of oligomeric compounds, particularly oligonucleotides and oligonucleotide mimetics, are provided. In addition, methods for functionalizing a support medium with a first monomeric subunit and methods for the synthesis of oligomeric compounds utilizing the novel compounds bound to support media are provided.

专利号:WO-03064360-A1
优先权日:2002-02-01
标 题:Synthetic tetraethers and synthesis strategies therefor
发明人：KUEHL CHRISTINE; LITTGER RALF
权利人:BERNINA BIOSYSTEMS GMBH; KUEHL CHRISTINE; LITTGER RALF
摘要:The invention relates to novel synthetic tetraethers and a novel method for producing said substances. The inventive tetraethers are characterised in that they can be modified in a simple and targeted manner according to said synthesis method, which enabling the synthesis of the desired model substances. The synthesis concept guarantees high variability with simple individual production.

专利号:EP-3967330-A1
优先权日:2020-09-10
标 题:Methods for the synthesis of bioactivated metal nanocluster and their medical application
发明人：MARCHI VALÉRIE; CHIECHIO REGINA MARIA; EVEN-HERNANDEZ PASCALE
权利人:UNIV RENNES; CENTRE NAT RECH SCIENT; INSTITUT NAT DES SCIENCES APPLIQUEES DE RENNES; ECOLE NAT SUPERIEURE DE CHIMIE DE RENNES
摘要:The present invention relates to a bioactivated metal nanocluster comprising a mixture of ligands linked to a fluorescent metallic nanocluster, their synthesis methods, and their medical applications.

专利号:US-7425443-B2
优先权日:1997-01-21
标 题:Treatment of diabetes with synthetic beta cells
发明人：ALAM TAUSIF; HULLETT DEBRA A; SOLLINGER HANS W
权利人:WISCONSIN ALUMNI RES FOUND
摘要:Disclosed is a method for obtaining glucose-regulated expression of active insulin in the cells of a mammalian subject. The method involves delivering into the subject a genetic construct comprising a coding sequence for a human proinsulin operably connected a promoter functional in the host cells. The construct includes a glucose responsive regulatory module having at least one glucose inducible regulatory element comprising a pair of CACGTG motifs linked by a five base nucleotide sequence, which confers glucose inducible expression of the proinsulin coding sequence. To ensure proper processing of the proinsulin to active insulin, the coding sequence was modified to direct the synthesis of a mutant proinsulin polypeptide having amino acid sequences that can be cleaved to mature insulin in suitable host cells, such as hepatocytes.