CAS: 1256823-65-0; 5-Bromo-6-Chloropicolinonitrile

相似化合物

959958-25-9 1053659-39-4 185017-72-5

📜3-溴-2-氯吡啶置于间氯过氧苯甲酸,二甲氨基甲酰氯体系中,用 二氯甲烷,水,1,2-二氯乙烷 用作溶剂,化学反应 79.0H,反应生成5-溴-6-氯吡啶-2-甲腈
参考文献:Novel Bicyclic Pyridinones
标题:Novel Bicyclic Pyridinones
摘要:所述化合物及其药用可接受的盐被披露,其中所述化合物具有如本文所定义的formula I的结构.相应的药物组合物,治疗方法,合成方法和中间体也被披露.

专利信息

专利号:US-9067934-B2
优先权日:2011-03-31
标题 :Bicyclic pyridinones
发明人：PETTERSSON MARTIN YOUNGJIN; JOHNSON DOUGLAS SCOTT; SUBRAMANYAM CHAKRAPANI; O'DONNELL CHRISTOPHER JOHN; AM ENDE CHRISTOPHER WILLIAM; FISH BENJAMIN ADAM; GREEN MICHAEL ERIC; MULLINS PATRICK BRADLEY; STIFF CORY MICHAEL; TRAN TUAN PHONG; NAVARATNAM THAYALAN
权利人:PFIZER
摘要:Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula I n nas defined herein. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.

专利号:US-2012202787-A1
优先权日:2009-10-20
标 题:Novel Heteroaryl Imidazoles And Heteroaryl Triazoles As Gamma-Secretase Modulators
发明人：AM ENDE CHRISTOPHER WILLIAM; JOHNSON DOUGLAS SCOTT; PETTERSSON MARTIN YOUNGJIN; SUBRAMANYAM CHAKRAPANI; O'DONNELL CHRISTOPHER JOHN
权利人:AM ENDE CHRISTOPHER WILLIAM; JOHNSON DOUGLAS SCOTT; PETTERSSON MARTIN YOUNGJIN; SUBRAMANYAM CHAKRAPANI; O'DONNELL CHRISTOPHER JOHN; PFIZER
摘要:Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula I; n n n n n n n n n n as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.